Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Ubiquinone biosynthesis O-methyltransferase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12375 g12375.t1 TTS g12375.t1 23159131 23159131
chr_1 g12375 g12375.t1 isoform g12375.t1 23159484 23160329
chr_1 g12375 g12375.t1 exon g12375.t1.exon1 23159484 23160046
chr_1 g12375 g12375.t1 cds g12375.t1.CDS1 23159484 23160046
chr_1 g12375 g12375.t1 exon g12375.t1.exon2 23160110 23160329
chr_1 g12375 g12375.t1 cds g12375.t1.CDS2 23160110 23160329
chr_1 g12375 g12375.t1 TSS g12375.t1 23160384 23160384

Sequences

>g12375.t1 Gene=g12375 Length=783
ATGAATGCAGAGCAACAATCAGTGTTTGAGAAAAAAAATGTTGATCCAAAAGACATCAAA
AGATTCAATAAGCAATCGAAAGAATGGTGGGATTTAAATGGAGTCCAACATATGTTGCAT
GCCATGAATTACATGAGAGTTCCTTGGGTTTGTGATGGTCTAAAAGAGACAAATTATATC
AGTAAAGATGCAACAAATCTCGAAGGATGTTTGATTTTAGATGCTGGCTGTGGAGGAGGA
ATTTATGCTGAAGGTTTAGCAAAGTTGGGTGCAAAAGTTATTGGTTTAGATTGTGCTAGA
GAGTTGTTGGATGTTGCACAAAATCATCTCAATACACAACATGATATTAAAGATAAAGTG
ACTTATGTTTGTGAGACTATTGAAGAACATTGCTTAAAAAATGAGAACAAATATGATGCA
ATTGTGTGCAGTGAAGTTATCGAACATATTATCGATAAAAATTCATTCCTTGAAGCTTGC
ATTAAAACACTTAAACCTGGTGGAAGTATTTTTATGACAACAATCAGTCACACTTTTGCT
GCTTGGTTTTTCGCTAAATTATGGGGCGAATATATTTTGGGTTTGATTGAAAGAGGAACT
CACGATCCAAAACTTTTTATTGATCACAAGGATTTATCAAAAATTCTGGAAAAATACAAT
GCAAAGACAGTGTCAGTGAAAGGAACTTCTTATGACTTCTTTAGAAGGCGACAAGATAAG
AAATGGCACTTTGGACCATTCACTATGGTTTCTTATGCACTTCAGGCAGTGAAGCAAAGT
TAA

>g12375.t1 Gene=g12375 Length=260
MNAEQQSVFEKKNVDPKDIKRFNKQSKEWWDLNGVQHMLHAMNYMRVPWVCDGLKETNYI
SKDATNLEGCLILDAGCGGGIYAEGLAKLGAKVIGLDCARELLDVAQNHLNTQHDIKDKV
TYVCETIEEHCLKNENKYDAIVCSEVIEHIIDKNSFLEACIKTLKPGGSIFMTTISHTFA
AWFFAKLWGEYILGLIERGTHDPKLFIDHKDLSKILEKYNAKTVSVKGTSYDFFRRRQDK
KWHFGPFTMVSYALQAVKQS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g12375.t1 CDD cd02440 AdoMet_MTases 72 173 0.00000
6 g12375.t1 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 18 259 0.00000
4 g12375.t1 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 18 259 31.71678
2 g12375.t1 PANTHER PTHR43464 METHYLTRANSFERASE 5 253 0.00000
3 g12375.t1 PANTHER PTHR43464:SF25 UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL 5 253 0.00000
1 g12375.t1 Pfam PF08241 Methyltransferase domain 73 171 0.00000
5 g12375.t1 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases 22 239 0.00000
7 g12375.t1 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 19 238 0.00000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity MF
GO:0008168 methyltransferase activity MF
GO:0006744 ubiquinone biosynthetic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed