General information for g12696.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit.
Parent gene
- The parent gene g12696 is located on chr_1: 25323738..25325043 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12696 | g12696.t1 | TTS | g12696.t1 | 25322138 | 25322138 |
| chr_1 | g12696 | g12696.t1 | isoform | g12696.t1 | 25322637 | 25324690 |
| chr_1 | g12696 | g12696.t1 | exon | g12696.t1.exon1 | 25322637 | 25322917 |
| chr_1 | g12696 | g12696.t1 | cds | g12696.t1.CDS1 | 25322637 | 25322917 |
| chr_1 | g12696 | g12696.t1 | exon | g12696.t1.exon2 | 25322980 | 25323745 |
| chr_1 | g12696 | g12696.t1 | cds | g12696.t1.CDS2 | 25322980 | 25323745 |
| chr_1 | g12696 | g12696.t1 | exon | g12696.t1.exon3 | 25323805 | 25324298 |
| chr_1 | g12696 | g12696.t1 | cds | g12696.t1.CDS3 | 25323805 | 25324298 |
| chr_1 | g12696 | g12696.t1 | exon | g12696.t1.exon4 | 25324360 | 25324513 |
| chr_1 | g12696 | g12696.t1 | cds | g12696.t1.CDS4 | 25324360 | 25324513 |
| chr_1 | g12696 | g12696.t1 | exon | g12696.t1.exon5 | 25324613 | 25324690 |
| chr_1 | g12696 | g12696.t1 | cds | g12696.t1.CDS5 | 25324613 | 25324690 |
| chr_1 | g12696 | g12696.t1 | TSS | g12696.t1 | 25324906 | 25324906 |
Sequences
>g12696.t1 Gene=g12696 Length=1773
ATGGCGGACCAAAAAAGCGATGATTCACTTTATCCTATTGCTGTTCTAATTGATGAATTA
AAGAATGAAGATATTCAGCTCCGATTAAACTCGATTAAAAAATTGTCAACAATTGCATTA
GCTCTTGGTGAAGAGAGGACTAGAACTGAGTTGGTTCCGTTTTTGACAGAGACGATTTAT
GATGAAGATGAAGTTTTACTTGCACTTGCCGAGCAGCTGGGAACTTTCACACATCTTGTT
GGTGGACCAGATTACGCGATGTATTTAATTCCTCCTTTAGAGAGTTTGGCTACTGTTGAA
GAAACAGTCGTTCGTGATAAGGCAGTTGAATCACTTCGTAATGTTGCTGCACAACATAGT
GCTCACGACTTGGAAGTTCATGTTATTCCAACACTTCAACGTTTGGTTTCTGGCGAATGG
TTTACATCGCGCACATCAGCATGTGGATTATTTTCTGTTTGCTATCCTCGCGTGCCAGCA
TCAGTCAAGGCTGAATTGCGCAATTTATTTAGACAATTGTGTCAAGATGAGACTCCTATG
GTTCGTCGTGCGGCTGCAGGCAAATTAGGAGAGTTTGCTAAAGTGGTGGAAGTTGAATTT
CTCAAGTCAGATTTGATTCCAATGTTTGTTCAATTGGCTCAGGATGATCAAGATTCTGTA
CGCTTACTTGCTGTAGAGGCATGTGTTAGTATTGCTCAACTTTTACAACAAGAGGATGTT
GAAACGTTGGTGATGCCAACTCTTCGTCAATGTGCTAGCGATTCGTCCTGGCGTGTTCGA
TATGTTGTGGCTGAGAAATTTGTTGATCTACAAAAAGCTGTTGGTCCAGAAATTACAAAA
ACTGATCTTGTTCCAGCTTTTCAATATTTACTTAAAGATACAGAGGCCGAAGTTCGTGCT
TCTGCTGCAACCAAAGTCAAAGACTTTTGTGCAAACTTAGATCCAACAAATCGCGAACAA
ATTATAATGACGTCAATATTGCCATACATCAAGGAATTAGTATCTGATGCAAATCAACAC
GTCAAATCGGCACTCGCTTCAGTCATTATGGGATTAAGTCCAATATTTGGGCGAAACAAC
ACGATCGAACATTTGCTTCCTCTGTTTTTGACTCAATTGACTGATGAATGGCCAGAAGTT
CGTCTCAACATTATATCCACATTAGATTGCATAAATGATGTTATTGGAATTCAACAGCTC
TCACAGTCTCTTTTGCCAGCAATTGTGGAACTTGCAGAAGATTCCAAATGGCGGGTTCGA
TTAGCTATTATCGAATATATGCCATTATTGGCAGGTCAACTTGGTCAAGATTACTTTAAT
CAGAAATTAAGAGATTTGTGCTTCAATTGGCTTAATGATCACGTTTATGCTATCCGCGAG
GCTGCCACATTAAATATGAAAAAGATTGTTCAGACATTCGGCACACAGTGGGCAGAAACA
AATATTATTCCACAGATTTTGGTCATGTGCAAAAACAATAACTACTTGCATAGAATGACA
TGTCTTTTCTGTATTAATGCTTTAGCTGATGTTGTTGGTGCAGATGTTATTAAGAGATTG
TTCTTACCTACCATTAAGACATTGTCTACCGATCCTGTTGCAAATGTTCGTTTCAATGTT
GCAAAAACTTTATCTAAAATCTCAGCGTTCTTAGATACAGCAACGACAGAAGCCGAAGTA
AAGCCCATACTCGAACAACTGAATACAGATGCAGACGTTGACGTTAAATATTTTGCATCG
GAGGCAATTTCAACTATTGCAGCGAGTGCTTAA
>g12696.t1 Gene=g12696 Length=590
MADQKSDDSLYPIAVLIDELKNEDIQLRLNSIKKLSTIALALGEERTRTELVPFLTETIY
DEDEVLLALAEQLGTFTHLVGGPDYAMYLIPPLESLATVEETVVRDKAVESLRNVAAQHS
AHDLEVHVIPTLQRLVSGEWFTSRTSACGLFSVCYPRVPASVKAELRNLFRQLCQDETPM
VRRAAAGKLGEFAKVVEVEFLKSDLIPMFVQLAQDDQDSVRLLAVEACVSIAQLLQQEDV
ETLVMPTLRQCASDSSWRVRYVVAEKFVDLQKAVGPEITKTDLVPAFQYLLKDTEAEVRA
SAATKVKDFCANLDPTNREQIIMTSILPYIKELVSDANQHVKSALASVIMGLSPIFGRNN
TIEHLLPLFLTQLTDEWPEVRLNIISTLDCINDVIGIQQLSQSLLPAIVELAEDSKWRVR
LAIIEYMPLLAGQLGQDYFNQKLRDLCFNWLNDHVYAIREAATLNMKKIVQTFGTQWAET
NIIPQILVMCKNNNYLHRMTCLFCINALADVVGADVIKRLFLPTIKTLSTDPVANVRFNV
AKTLSKISAFLDTATTEAEVKPILEQLNTDADVDVKYFASEAISTIAASA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12696.t1 | Gene3D | G3DSA:1.25.10.10 | - | 2 | 588 | 0.000 |
| 3 | g12696.t1 | PANTHER | PTHR10648 | SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT | 2 | 588 | 0.000 |
| 4 | g12696.t1 | PANTHER | PTHR10648:SF9 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM | 2 | 588 | 0.000 |
| 2 | g12696.t1 | Pfam | PF13646 | HEAT repeats | 169 | 264 | 0.000 |
| 1 | g12696.t1 | Pfam | PF13646 | HEAT repeats | 366 | 466 | 0.000 |
| 13 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 12 | 50 | 9.506 |
| 11 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 166 | 204 | 10.658 |
| 12 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 205 | 243 | 13.608 |
| 10 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 244 | 282 | 11.950 |
| 14 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 283 | 320 | 10.602 |
| 16 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 326 | 364 | 11.163 |
| 7 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 365 | 403 | 11.135 |
| 9 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 404 | 442 | 12.850 |
| 15 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 521 | 559 | 11.332 |
| 8 | g12696.t1 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 560 | 590 | 9.590 |
| 5 | g12696.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 8 | 585 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K03456 (serine/threonine-protein phosphatase 2A regulatory subunit A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
