Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldo-keto reductase family 1 member B10.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12728 g12728.t9 isoform g12728.t9 25507377 25508906
chr_1 g12728 g12728.t9 exon g12728.t9.exon1 25507377 25507765
chr_1 g12728 g12728.t9 TTS g12728.t9 25507381 25507381
chr_1 g12728 g12728.t9 cds g12728.t9.CDS1 25507464 25507765
chr_1 g12728 g12728.t9 exon g12728.t9.exon2 25507847 25508414
chr_1 g12728 g12728.t9 cds g12728.t9.CDS2 25507847 25508414
chr_1 g12728 g12728.t9 exon g12728.t9.exon3 25508849 25508906
chr_1 g12728 g12728.t9 cds g12728.t9.CDS3 25508849 25508878
chr_1 g12728 g12728.t9 TSS g12728.t9 25508972 25508972

Sequences

>g12728.t9 Gene=g12728 Length=1015
ATGGCAGCACCTACTGTTACTCTCAATAATGGCAAACAATTTCCAATCGTTGGCCTTGTC
ACCACCTGGTGTTGTTGCTCAAGCTGTAAAAGACGCAATTGATGCTGGCTATCGTCATTT
TGACGGTGCTCATGTATATGAAAATGAGCATGAAGTTGGTGAAGGAATTAATGCTAAAAT
CGCTGAAGGTGTTATCAAACGTGAAGACGTTTTTGTAACATCAAAATTATGGTGCACTTT
CCATGACCCAAAGGATGTTCGTGGTGCACTCGAGCATACATTGAAACAATTAAATTTAGA
TTATCTTGACTTGTACCTCATGCATTGGCCTATTTGTTATCAAAAATCAACTGAATTGTT
CCCAAAGAATGAAGCTGGTGAAATTTTGCACGCTAATTTTGATATTCTTGACACTTATCG
TGCAATGGAGGAACTTGTTGATGCTGGATTGACTAAAAGTATTGGAATTTCAAACTTCAA
TATCAAACAAGTTGAGTACATTACTAAAAATGCTCGCATCCAACCAGTCACCAATCAAGT
TGAATGCAATCCATATTTACTTAATAAAGAATTAAGTGATTTCTGCAAAAGTAAAAACAT
TGTCATCACCGCTTATTCACCTCTTGGTCGTCCATGGGCAACACCAGATGACCGAGTATT
ATTAAAAGAACCAAAACTTTTAGAGATCGCTCAGAAGCACAATAAAACACCAGCACAAAT
TTTAATCCGTTACCAAATTCAACGCGGTCACGTTGTCATACCGAAATCAGTTACGAAGGA
TCGCATAATCAGTAATTTTGATGTTTTCAACTTCACATTGAGCGATTCTGAAATAAAAGA
TTTGGAAAACTTCAACTATACTGAGCGCATTTGTAGCATGTCTCAAGATAAACATCATCC
AGCTTATCCTTTCAATGACGACGCCTAAAAAATGCACCGCCTGCCTCTTTTTTGATTGTC
TGATTATCAAAAAAATGAAATAAATGTGGAACACACAGTTTCTTTTCAAATAAAA

>g12728.t9 Gene=g12728 Length=299
MANNFQSLALSPPGVVAQAVKDAIDAGYRHFDGAHVYENEHEVGEGINAKIAEGVIKRED
VFVTSKLWCTFHDPKDVRGALEHTLKQLNLDYLDLYLMHWPICYQKSTELFPKNEAGEIL
HANFDILDTYRAMEELVDAGLTKSIGISNFNIKQVEYITKNARIQPVTNQVECNPYLLNK
ELSDFCKSKNIVITAYSPLGRPWATPDDRVLLKEPKLLEIAQKHNKTPAQILIRYQIQRG
HVVIPKSVTKDRIISNFDVFNFTLSDSEIKDLENFNYTERICSMSQDKHHPAYPFNDDA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g12728.t9 Gene3D G3DSA:3.20.20.100 - 5 299 1.1E-121
2 g12728.t9 PANTHER PTHR11732:SF294 ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 10 297 5.9E-112
3 g12728.t9 PANTHER PTHR11732 ALDO/KETO REDUCTASE 10 297 5.9E-112
14 g12728.t9 PIRSF PIRSF000097 AKR 5 299 2.2E-117
4 g12728.t9 PRINTS PR00069 Aldo-keto reductase signature 23 47 4.2E-57
8 g12728.t9 PRINTS PR00069 Aldo-keto reductase signature 83 101 4.2E-57
5 g12728.t9 PRINTS PR00069 Aldo-keto reductase signature 133 150 4.2E-57
7 g12728.t9 PRINTS PR00069 Aldo-keto reductase signature 167 196 4.2E-57
6 g12728.t9 PRINTS PR00069 Aldo-keto reductase signature 211 235 4.2E-57
1 g12728.t9 Pfam PF00248 Aldo/keto reductase family 16 274 3.6E-53
11 g12728.t9 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 27 44 -
10 g12728.t9 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 -
12 g12728.t9 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 244 259 -
9 g12728.t9 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 12 293 1.18E-91

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed