Gene loci information

Transcript annotation

  • This transcript has been annotated as Gelsolin, cytoplasmic.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1278 g1278.t17 TTS g1278.t17 9412202 9412202
chr_3 g1278 g1278.t17 isoform g1278.t17 9413023 9413563
chr_3 g1278 g1278.t17 exon g1278.t17.exon1 9413023 9413563
chr_3 g1278 g1278.t17 cds g1278.t17.CDS1 9413023 9413532
chr_3 g1278 g1278.t17 TSS g1278.t17 NA NA

Sequences

>g1278.t17 Gene=g1278 Length=541
TAAGAAAAGTGGTGGTCGTGCACTTGGCTTCATGCCAGATAATGGAGAAGGTGAAGCTGA
AGTCTTTAGAGTTGAAAATATGGAAATTGTGCCAATTCCAAAAGAAAATTATGGTTTCTT
TTTTGGTGGTGATTCTTATGTCATTAAATATGAATATAGAAATAAACGTGGTGGACATGG
ATATGTTATTTACTATTGGCAAGGGTTAACTTCATCAACTGATGAGAAAGCTGCATCAGC
AATTCATGCTGCAAAAATGAGCAGTGAAATAGGAGTAAAATCAATGCAAGTTCGTGTTGT
TCAAGGCTTTGAATCACGTCATTTCTTAAAAGTTTTTAAAGGAAAAATTGTGGTTTTAAC
TGGAGGAAAAGCCTCAGGCTTTAGAAATGTTCATGACCATGATTCTTATGATGTTGATGG
CACAAGATTGTTTAGAGTTCGTGGAACATGTGCTGATGATGTTCGTGCTAATCAAGTTGA
AGAGGTTGCCAAGTCGCTTGCATCTGATGATGTTTTCATTTTGGAAACACCGACAAATAC
T

>g1278.t17 Gene=g1278 Length=170
MPDNGEGEAEVFRVENMEIVPIPKENYGFFFGGDSYVIKYEYRNKRGGHGYVIYYWQGLT
SSTDEKAASAIHAAKMSSEIGVKSMQVRVVQGFESRHFLKVFKGKIVVLTGGKASGFRNV
HDHDSYDVDGTRLFRVRGTCADDVRANQVEEVAKSLASDDVFILETPTNT

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g1278.t17 CDD cd11293 gelsolin_S4_like 1 102 0.0e+00
10 g1278.t17 Gene3D G3DSA:3.40.20.10 Severin 3 132 0.0e+00
11 g1278.t17 Gene3D G3DSA:3.40.20.10 Severin 133 170 4.3e-06
2 g1278.t17 PANTHER PTHR11977 VILLIN 3 168 0.0e+00
4 g1278.t17 PRINTS PR00597 Gelsolin family signature 26 42 0.0e+00
3 g1278.t17 PRINTS PR00597 Gelsolin family signature 52 70 0.0e+00
6 g1278.t17 PRINTS PR00597 Gelsolin family signature 85 105 0.0e+00
5 g1278.t17 PRINTS PR00597 Gelsolin family signature 144 164 0.0e+00
1 g1278.t17 Pfam PF00626 Gelsolin repeat 17 99 0.0e+00
9 g1278.t17 SMART SM00262 VILL_6 7 105 0.0e+00
7 g1278.t17 SUPERFAMILY SSF55753 Actin depolymerizing proteins 3 139 0.0e+00
8 g1278.t17 SUPERFAMILY SSF55753 Actin depolymerizing proteins 122 167 2.8e-06

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0051015 actin filament binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values