General information for g12787.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Titin.
Parent gene
- The parent gene g12787 is located on chr_1: 26157218..26161147 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12787 | g12787.t1 | isoform | g12787.t1 | 26151423 | 26161147 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon1 | 26151423 | 26151704 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS1 | 26151423 | 26151704 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon2 | 26152269 | 26152647 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS2 | 26152269 | 26152647 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon3 | 26152710 | 26152933 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS3 | 26152710 | 26152933 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon4 | 26153436 | 26153807 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS4 | 26153436 | 26153807 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon5 | 26153870 | 26154000 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS5 | 26153870 | 26154000 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon6 | 26154260 | 26154550 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS6 | 26154260 | 26154550 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon7 | 26154631 | 26154834 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS7 | 26154631 | 26154834 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon8 | 26155684 | 26155797 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS8 | 26155684 | 26155797 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon9 | 26157218 | 26157289 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS9 | 26157218 | 26157289 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon10 | 26157361 | 26157382 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS10 | 26157361 | 26157382 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon11 | 26157498 | 26157612 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS11 | 26157498 | 26157612 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon12 | 26157710 | 26157839 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS12 | 26157710 | 26157839 |
| chr_1 | g12787 | g12787.t1 | exon | g12787.t1.exon13 | 26161036 | 26161147 |
| chr_1 | g12787 | g12787.t1 | cds | g12787.t1.CDS13 | 26161036 | 26161147 |
| chr_1 | g12787 | g12787.t1 | TSS | g12787.t1 | NA | NA |
| chr_1 | g12787 | g12787.t1 | TTS | g12787.t1 | NA | NA |
Sequences
>g12787.t1 Gene=g12787 Length=2448
ATGATTTTGAAAATTTACGATATCGTGGAGCTTACAGCGTTTATGCTATTGAAGCTGGTG
TTGTTTTTATGTCTGGCGCAAGGATACACAAAGAGCGAGAAAGAAAAGCTCGCTCCCATA
ACGAGCGTTGAGGCCATTGAGGGACAACAGACGCATCTTTACTGTCCTATGGCAACGCCA
AATGGTGACAAAATCAACATGGTATTGTGGTTTAAGGATGATGTTGGTGTACCCATTTAT
CGATTCGATGTTCGTGGAAAATCAATGTCAGATCCTACAGAATGGTCCGATGCGACCGTT
TTCGGAACTCGTGCCAAATTTATTACACAGTCTGAGCCAGCATATCTAGAGATAGATGAC
ATTAAACGACACGATCAAGGCATTTATCGTTGTCGTGTTGACTTCCAAACGAGTCAAACC
ATTAGTTTAAGATTTAATCTTACTGTTATAATTTTACCGGAAAATCCTATAATATTAGAT
CGATGGGGAAGAAGTATTAATAGAACAACCATTGGACCAATGGAAGAAGGCGATGATGTG
ATTTTATCATGTCGTGTTGTTGGTGGTCGACCTTTGCCTGATGTCTCATGGTTTCTTAAT
GGTGAACTCATCGATGACGAATTTGAGCATAATTCGGGCAATATCATAGAAAATCGTTTA
CTGTGGCCTTCAATAAAGCGTGACGACTTGTACTCGGTGTTTACGTGTCGTGCTGTCAAC
ACGAAAGCAGTAGCGCCTAGAGAAAAGCGTTTAGTTTTAGATATGTACCTTAAGCCAATT
TACGTGAATATTGTCAACAGCTCGTTAACACTTGTTGCCGATCGCAAATATGAGATTCAT
TGTATAACATCAGGGTCACGGCCTGATGCAATTATCACGTGGTATAAAGGCAAAAAGGCG
TTGAAACGAATACGTGACTACACCAAAAATAATGAAACGACGTCAATACTCAATTTTGTG
CCATCAATTGAGGACAATGGCAAGATGCTGACGTGTCATGCCGAGAATCCTAATGTTGCG
GGAATGTTTGTTGAGGATAGCTGGAATATGAGTGTTTTCTATCCACCAGTGATATCATTA
GAATTAGGCTCGAAGCTCCAACCGGGTGACATAAAAGAAGGCGATGATGTCTATTTTGAG
TGTAAGATTGAATCAAATCCCAAATTTAGGAAGTTAACTTGGCTGCATAATGGACGACCA
TTAAAAACAAATAGCAGCACAAAAATTGTAAAGTCAAATCAAAGTTTGGTGCTACAAAAA
GTGACGCGATTCTCAGCGGGCAAATACTCTTGCTCTGCACTCAACTCAGAGGGCGAAACA
GTGAGCAATGAATTTTCATTGAAAGTGAAATTCGTACCAATTTGTGCCACTGACAAGATG
ATGATTGTCGGTGCGACGAAAGGCGAAAATGTACAATTAAGTTGCGATGTAAAATCGTAT
CCAATACCAAAACGTTTCTATTGGAAATTTGAGAATTCAGAGGAATCTGTTGAGATAGAA
TCGAAGAAATTTACTAACAATGGCACGAGGAGTTTACTTAGCATCTCGACAGCAACAGAT
CATGATTATGGTAGCTTATCATGCTGGGCAAAAAACGAAATTGGCATTCAAACACAGCCG
TGTATTTTTCAATTAATTCTCGCTGGACCACCATCGGTGCTAACGAATTGTTCATGGACT
AATGAATCAGATTCGTCGCTCTCTGTCAATTGTAGTCCTAATTATGATGGTGGTCTACCA
CAAATTTTCATCCTCGAAGTTTATTCGTTAAAGCACAAAATTCAATTATTCAATATCACC
AATGCAGTTGAACCCACATTTAAATTTGACCCAAATCGTAGGATTTTTAATCGTTATAAA
AATTCAACTGAAAATGACATTCTACGTGTGAATGTTTTTGCAAAGAATCAAAAAGGTCGT
GGAGCTGGTGTTTTTATCACTGAATTTCATCTTGGCAATTATAAACGCAATCAAAGTGAT
CTCATAAAAGAATCATCAAGCCCTTCGCCCATAATTTTAGGACTTTTTCTTACACTCTTT
ATCATTGGAACGACAATCATATTAAGACTTTATTGGAAGTCAAGAAAAATTAAGAAGGAA
ATTGTTAAGGAGGATAAATATACTATGGAATCGAGATGTTCTTTATTGAAGCAGGATAAT
TTTGCTTCGGATGCTTTTTCAAGTCCTAAATTCCAAAAACCAACAGGCACGAGCATCAAA
ACGAGAGGGAAAATAGAGACTATAGATGATGAACAAGACCCCGATCTCATACCACACTAT
CCACGCCTCACTAGCATTCATCAAGAAGAATTAATACCAATGAATTCAGATCCATCATTT
CTCAATCGTGATAGACACAAAAATTCAACAAATGACTTTCTCCATGATGTTGAAATTAAT
TTCAATGGACTGCTTATGAATGGAAAAGTTCCCGAAAGTTGTGTATGA
>g12787.t1 Gene=g12787 Length=815
MILKIYDIVELTAFMLLKLVLFLCLAQGYTKSEKEKLAPITSVEAIEGQQTHLYCPMATP
NGDKINMVLWFKDDVGVPIYRFDVRGKSMSDPTEWSDATVFGTRAKFITQSEPAYLEIDD
IKRHDQGIYRCRVDFQTSQTISLRFNLTVIILPENPIILDRWGRSINRTTIGPMEEGDDV
ILSCRVVGGRPLPDVSWFLNGELIDDEFEHNSGNIIENRLLWPSIKRDDLYSVFTCRAVN
TKAVAPREKRLVLDMYLKPIYVNIVNSSLTLVADRKYEIHCITSGSRPDAIITWYKGKKA
LKRIRDYTKNNETTSILNFVPSIEDNGKMLTCHAENPNVAGMFVEDSWNMSVFYPPVISL
ELGSKLQPGDIKEGDDVYFECKIESNPKFRKLTWLHNGRPLKTNSSTKIVKSNQSLVLQK
VTRFSAGKYSCSALNSEGETVSNEFSLKVKFVPICATDKMMIVGATKGENVQLSCDVKSY
PIPKRFYWKFENSEESVEIESKKFTNNGTRSLLSISTATDHDYGSLSCWAKNEIGIQTQP
CIFQLILAGPPSVLTNCSWTNESDSSLSVNCSPNYDGGLPQIFILEVYSLKHKIQLFNIT
NAVEPTFKFDPNRRIFNRYKNSTENDILRVNVFAKNQKGRGAGVFITEFHLGNYKRNQSD
LIKESSSPSPIILGLFLTLFIIGTTIILRLYWKSRKIKKEIVKEDKYTMESRCSLLKQDN
FASDAFSSPKFQKPTGTSIKTRGKIETIDDEQDPDLIPHYPRLTSIHQEELIPMNSDPSF
LNRDRHKNSTNDFLHDVEINFNGLLMNGKVPESCV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 25 | g12787.t1 | CDD | cd00096 | Ig | 180 | 240 | 3.6946E-6 |
| 26 | g12787.t1 | CDD | cd00096 | Ig | 377 | 442 | 1.80487E-8 |
| 24 | g12787.t1 | CDD | cd00096 | Ig | 471 | 538 | 1.14996E-6 |
| 16 | g12787.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 33 | 155 | 9.3E-15 |
| 14 | g12787.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 156 | 256 | 4.4E-13 |
| 13 | g12787.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 262 | 357 | 9.5E-17 |
| 12 | g12787.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 364 | 455 | 2.4E-17 |
| 15 | g12787.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 456 | 546 | 1.1E-12 |
| 6 | g12787.t1 | PANTHER | PTHR23278 | SIDESTEP PROTEIN | 31 | 699 | 1.9E-203 |
| 1 | g12787.t1 | Pfam | PF07686 | Immunoglobulin V-set domain | 42 | 149 | 2.5E-6 |
| 4 | g12787.t1 | Pfam | PF13927 | Immunoglobulin domain | 174 | 240 | 1.1E-7 |
| 2 | g12787.t1 | Pfam | PF08205 | CD80-like C2-set immunoglobulin domain | 272 | 338 | 2.2E-8 |
| 5 | g12787.t1 | Pfam | PF07679 | Immunoglobulin I-set domain | 364 | 449 | 2.5E-13 |
| 3 | g12787.t1 | Pfam | PF13927 | Immunoglobulin domain | 465 | 532 | 2.2E-10 |
| 19 | g12787.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 26 | - |
| 20 | g12787.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 10 | - |
| 21 | g12787.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 11 | 22 | - |
| 23 | g12787.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 23 | 26 | - |
| 18 | g12787.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 27 | 670 | - |
| 22 | g12787.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 671 | 692 | - |
| 17 | g12787.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 693 | 815 | - |
| 39 | g12787.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 33 | 142 | 9.682 |
| 40 | g12787.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 153 | 252 | 9.827 |
| 41 | g12787.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 259 | 351 | 8.43 |
| 37 | g12787.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 355 | 442 | 13.003 |
| 38 | g12787.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 453 | 532 | 9.283 |
| 31 | g12787.t1 | SMART | SM00409 | IG_3c | 40 | 150 | 3.8E-4 |
| 36 | g12787.t1 | SMART | SM00408 | igc2_5 | 46 | 138 | 0.52 |
| 29 | g12787.t1 | SMART | SM00409 | IG_3c | 169 | 256 | 100.0 |
| 35 | g12787.t1 | SMART | SM00408 | igc2_5 | 175 | 243 | 0.023 |
| 32 | g12787.t1 | SMART | SM00409 | IG_3c | 266 | 353 | 17.0 |
| 30 | g12787.t1 | SMART | SM00409 | IG_3c | 366 | 450 | 1.7E-6 |
| 34 | g12787.t1 | SMART | SM00408 | igc2_5 | 372 | 438 | 5.6E-6 |
| 28 | g12787.t1 | SMART | SM00409 | IG_3c | 460 | 548 | 1.6 |
| 33 | g12787.t1 | SMART | SM00408 | igc2_5 | 466 | 535 | 0.099 |
| 11 | g12787.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 39 | 153 | 1.57E-10 |
| 10 | g12787.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 170 | 259 | 3.91E-12 |
| 9 | g12787.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 269 | 356 | 2.67E-12 |
| 8 | g12787.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 352 | 453 | 5.04E-18 |
| 7 | g12787.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 467 | 551 | 1.29E-11 |
| 27 | g12787.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 670 | 692 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed