Gene loci information

Transcript annotation

  • This transcript has been annotated as Molybdenum cofactor sulfurase 3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12792 g12792.t1 isoform g12792.t1 26220845 26226528
chr_1 g12792 g12792.t1 exon g12792.t1.exon1 26220845 26222402
chr_1 g12792 g12792.t1 cds g12792.t1.CDS1 26220845 26222402
chr_1 g12792 g12792.t1 exon g12792.t1.exon2 26222463 26222607
chr_1 g12792 g12792.t1 cds g12792.t1.CDS2 26222463 26222607
chr_1 g12792 g12792.t1 exon g12792.t1.exon3 26223977 26225946
chr_1 g12792 g12792.t1 cds g12792.t1.CDS3 26223977 26225946
chr_1 g12792 g12792.t1 exon g12792.t1.exon4 26226006 26226150
chr_1 g12792 g12792.t1 cds g12792.t1.CDS4 26226006 26226150
chr_1 g12792 g12792.t1 exon g12792.t1.exon5 26226459 26226528
chr_1 g12792 g12792.t1 cds g12792.t1.CDS5 26226459 26226528
chr_1 g12792 g12792.t1 TSS g12792.t1 26226646 26226646
chr_1 g12792 g12792.t1 TTS g12792.t1 NA NA

Sequences

>g12792.t1 Gene=g12792 Length=3888
ATGGATTTTATTAACGAATTTAATGAGAAAGAGATTGAAAAGATTAAAAGTGATTTTACA
AGATTAAAAGACACAACATATCTTGATACAACAGGAGCAGCACTTTATGGAGAAAGTCAA
ATGCGAGAAGTTTGTCAAGTATTGACTTCAAATCTAATCAGTAGTCCACACACATCAAAG
GCAACTGGAAATATTATTGATCAAGTTCGTTATAGAGTGCTTAAACACTTCAATGCTGAC
CCAGATGAATATTCAATTATTTTTACATCGGGTTGCACAGCTGCACTTAAAATTGTTGGT
GAATGTTTCCAATTTGGTGATAATGGTGCCTTTTATTATCTCACTGATTCTCACACATCA
GTTTTGGGTCTTCGAGAAATTGTTCAGACTGACAAAATTATTCCTGTTTCTGAGACAATG
CTAAGTGTTATCAACATGATGCATGGAGGAACTTCATTGCTTGTTTTTCCAGCTCAATGC
AATTATAATGGACAAAAATATTCACTAGATATAATTAAAAAAGTTCATGAAAATCCAAAC
ATGTTTGTTCTGCTTGATGCTGCTGCTTTTGTATCAACAAACAAGCTTGATTTGAGTATT
TATAAACCAAATTATGTCGCTCTTTCATTCTACAAAATTTTTGGCACTCCAACTGGTCTC
GGTGCTTTGATTATTTCAAAAAGAGGAGCTGAAAACTTAAATAAAAAGTATTATGGAGGT
GGAACTGTCAAAATTGCATTAACACGTGAAAATTGGCATGAAAAGCGTGATGGAATTTCT
GAAAAATTTGAAGATGGAACACCAAATTTTCAAGGAATTTTGAGTCTTCACACATCATTT
AAATATTTTGAAAATTTACTTGGCGACGAATTTATTGAAAGAATTTCAAGGCATGTTTTT
AATTTGGGAAAATATTTCTATCATTATATGAAGAGTTTTAAGCATTACAATCAACAACCA
GTGACAATTTTCTATCATAATTCTGATTTTGATGATATTCAAACTCAAGGTGGTGTTGTG
ACATTCAATTTAAAACGACCTGATGGATCTTTTGTTGGTTTTGCTGAATTTGCCAGTATT
GCAGCACTTCATAATATCATAATTAGAACAGGTTGCTTTTGCAATCCTGGAGCCTGTCAA
ACGCACTTGAAGTTAACAAATAAAGATTTAAAGAAGCACTTTGATGCCGGTCATGTGTGT
GGTGATTTGAATGATTTAGTTGATGGAATACCCACAGGCTGTATTCGAGTTTCATTTGGA
TACATGAATACAAAAGAAGATGTCGATAAATTACTGAAAATCGTTGAATCTTGTTATGTT
CAAAAAGTCGAGAATTTTGAAATTGATAAACCAAAAGAAATACTTAATGGTGAATCAAAA
GCAATTTTGAAATCAATAAGAATTTACCCAATAAAATCATGTGGAGCAATGAAAATTGAC
ACTGAATGGCCACTCTCACGAACAGGTTTAAAATATGATCGTGAATGGATGATAATGAAT
GGAAACAATGGAACATCATTAACTCAAAAGAATGAGCCAAAAATGTGCATGATTTGGCCA
TACATTGATGAAAGCAAAAACACATTACGGCTCGATTTTCCGCATTCTAATTCAATAGAA
GTTTTACTAAATGACAACAAAACCGGAGGAAAGCAATTAGAAGCTTCTATTTGTGAAACA
AAAGTGTGTGGTGATCGAATAAATGGAATTGATTGTGGTGATGAAGTAGCAAAATGGCTT
AGTGATGTTCTTATGATGGAAAATTTACGGTTGATTAGGCAAATTAATCAAAATGAGAGG
AAAAATGGAAAAGAAATTGCATTGGCAAATCAAGCGCAATTTCTTCTTATTAGTGAAGCA
TCAGTTCAATGGCTTATGAATCAAGTTGAAAGTTGGGACAATGATGAGAAAAATATGGAA
AATGTTATCGATAGATTTCGTGGAAACTTCATAATTGAAAACCTTGAAGCATTGGCTGAA
AATAATTGGAAATGTTTGAAAATTGGTGATGAAAATACTTTTCATATCGAAGGTCCATGC
ACTCGATGTCAGATGATTTGTATTGATCAAAATACAGGAGAAAAAACTACTGAACCATTA
AGAACGATGGGAAAAGTTTTTAATGGAAAAACTAAATTTGGAATTTATTTAAAAATGTTG
AAAAATTCGAGCGTGATAAGATGTGACACAACATATCTCGATACAACAGGAGCAGCACTT
TATGGAGAAAGTCAAATGCGAGAAGTTTGTCAAGTACTGACAACAAATCTCATCAGTAAT
CCACACTCATCGAAAGTTACTGAAGACATAATTGATAAAGTTCGTCAAAGAGTGCTTAAA
CACTTCAATGCTGACCCAGATGATTATTCAATTATTTTTACATCGGGTTGCACAGCTGCA
CTTAAAATTGTTGGTGAATGTTTTCAATTTGGTGATAATGGTGCCTTTTATTATTTTGCT
AACTCTCTACATACATCAGTTTTGGGTCTTCGAGAAATTGTTCAGACTGACAAAATCATT
CCTGTTTCTGAATCAATGCTAAGTGTTATCAACATGAAACATAATGGAAGTTCATTGTTT
ACTTATCCTGCTCAATGCAATTATAATGGACAAAAATATTCACTGAAAATCATAGAAAAA
GTTCATGAAAATCCAAACATGTTTGTTCTTCTTGATGCTGCTGCTTTTTTGTCAACAAGT
AAACTTGATATGAGCATATATAAACCAGATTATGTCGCTCTATCATTCTACAAAATTTTT
GGCACTCCAACTGGTCTTGGTGCTTTGATTATTTCAAAAAGAGGAGCTGAAAATTTAAAG
AAAAAATATTATGGAGGTGGAACTGTGAAATATGCTTTAGCAAAAGATATGAATTGGCAT
GAAAAACGTGATGGGATTTCTGAAAAATTTGAAGATGGAACACCAAATTTTCAAGGAATT
TTGAGTCTTCACACATCATTTAAATACTTTGAAAATTTACTTGGCGACGAATTTATCGAA
AGAATTTCAAGTCATGTTTTTAATTTGGGAAAATATTTCTATCATAATATGAAGAGTTTT
AAGCATTACAATCAACAACCAGTGACAATATTCTATCATAACTCTGATTTTGATGATATT
CAAACTCAAGGCGGTGTTGTGACATTCAATTTAAAACGACCAGATGGATCTTTTGTTGGG
TACACCGAATTTGCAAGTATTGCAGCACTTCATAATATCATAATTAGAACAGGATGCTTT
TGTAATTCTGGAGCATGTCAAACACACTTAAAATTCACAACTGAAGAAATTATGGATCGG
CTTCATGCTGGTTTTATTTGTGGTGATTCAAATGATTTAATTAATGATAAACCTACAGGC
TGCATTCGTGTTTCATTTGGTTATATGAATACAAAAAGAGATGTTGATAAATTATTGAAA
ATCGTTGAATTTTGTTATGTTCAAAAATCTGCAAATGTTGAAATTCGTGAATCAAAAAAA
ATTAATTTTGATAAATCAAAGTCAGTTTTTGAATTGACTACAGTTAATTCAATAAAAAAT
AAAGAATCTACTGAATGGCCACTCTCACGAACAGGTTTAAAATATGATCGTGAATGGATG
ATAATTAATGGAAACAATGGAACATCATTAACTCAAAAGAATGAGCCAAAAATGTGCATG
ATTCGACCATACATTGATGAAAGCAAAAACACATTAAGACACAATTTTCCGCATTCTAAT
TCAATTGAAGTTTTACTTGATGACAAGCAATTAGAAGGTTCAAAATGCGAAACAAAAGTG
TGTGATGAACAAATTATTGAAATTAATTGTAGTAAAAAGCAAAAGTTTAAATTTAGGCAG
GATTTTATCAGTTCCATGGAAATCTGTCAAAAATGTGCGAAAAGATAG

>g12792.t1 Gene=g12792 Length=1295
MDFINEFNEKEIEKIKSDFTRLKDTTYLDTTGAALYGESQMREVCQVLTSNLISSPHTSK
ATGNIIDQVRYRVLKHFNADPDEYSIIFTSGCTAALKIVGECFQFGDNGAFYYLTDSHTS
VLGLREIVQTDKIIPVSETMLSVINMMHGGTSLLVFPAQCNYNGQKYSLDIIKKVHENPN
MFVLLDAAAFVSTNKLDLSIYKPNYVALSFYKIFGTPTGLGALIISKRGAENLNKKYYGG
GTVKIALTRENWHEKRDGISEKFEDGTPNFQGILSLHTSFKYFENLLGDEFIERISRHVF
NLGKYFYHYMKSFKHYNQQPVTIFYHNSDFDDIQTQGGVVTFNLKRPDGSFVGFAEFASI
AALHNIIIRTGCFCNPGACQTHLKLTNKDLKKHFDAGHVCGDLNDLVDGIPTGCIRVSFG
YMNTKEDVDKLLKIVESCYVQKVENFEIDKPKEILNGESKAILKSIRIYPIKSCGAMKID
TEWPLSRTGLKYDREWMIMNGNNGTSLTQKNEPKMCMIWPYIDESKNTLRLDFPHSNSIE
VLLNDNKTGGKQLEASICETKVCGDRINGIDCGDEVAKWLSDVLMMENLRLIRQINQNER
KNGKEIALANQAQFLLISEASVQWLMNQVESWDNDEKNMENVIDRFRGNFIIENLEALAE
NNWKCLKIGDENTFHIEGPCTRCQMICIDQNTGEKTTEPLRTMGKVFNGKTKFGIYLKML
KNSSVIRCDTTYLDTTGAALYGESQMREVCQVLTTNLISNPHSSKVTEDIIDKVRQRVLK
HFNADPDDYSIIFTSGCTAALKIVGECFQFGDNGAFYYFANSLHTSVLGLREIVQTDKII
PVSESMLSVINMKHNGSSLFTYPAQCNYNGQKYSLKIIEKVHENPNMFVLLDAAAFLSTS
KLDMSIYKPDYVALSFYKIFGTPTGLGALIISKRGAENLKKKYYGGGTVKYALAKDMNWH
EKRDGISEKFEDGTPNFQGILSLHTSFKYFENLLGDEFIERISSHVFNLGKYFYHNMKSF
KHYNQQPVTIFYHNSDFDDIQTQGGVVTFNLKRPDGSFVGYTEFASIAALHNIIIRTGCF
CNSGACQTHLKFTTEEIMDRLHAGFICGDSNDLINDKPTGCIRVSFGYMNTKRDVDKLLK
IVEFCYVQKSANVEIRESKKINFDKSKSVFELTTVNSIKNKESTEWPLSRTGLKYDREWM
IINGNNGTSLTQKNEPKMCMIRPYIDESKNTLRHNFPHSNSIEVLLDDKQLEGSKCETKV
CDEQIIEINCSKKQKFKFRQDFISSMEICQKCAKR

Protein features from InterProScan

Transcript Database ID Name Start End E.value
18 g12792.t1 Gene3D G3DSA:3.40.640.10 - 40 283 0.00000
15 g12792.t1 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 284 441 0.00000
17 g12792.t1 Gene3D G3DSA:3.40.640.10 - 747 989 0.00000
16 g12792.t1 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 990 1148 0.00000
10 g12792.t1 Hamap MF_03050 Molybdenum cofactor sulfurase [MOCOS]. 6 728 20.93422
7 g12792.t1 PANTHER PTHR14237:SF67 MOLYBDENUM COFACTOR SULFURASE 11 705 0.00000
9 g12792.t1 PANTHER PTHR14237 MOLYBDOPTERIN COFACTOR SULFURASE MOSC 11 705 0.00000
6 g12792.t1 PANTHER PTHR14237:SF67 MOLYBDENUM COFACTOR SULFURASE 728 1162 0.00000
8 g12792.t1 PANTHER PTHR14237 MOLYBDOPTERIN COFACTOR SULFURASE MOSC 728 1162 0.00000
4 g12792.t1 Pfam PF00266 Aminotransferase class-V 39 431 0.00000
3 g12792.t1 Pfam PF03476 MOSC N-terminal beta barrel domain 462 585 0.00000
1 g12792.t1 Pfam PF03473 MOSC domain 605 725 0.00000
5 g12792.t1 Pfam PF00266 Aminotransferase class-V 755 1138 0.00000
2 g12792.t1 Pfam PF03476 MOSC N-terminal beta barrel domain 1177 1256 0.00000
19 g12792.t1 ProSiteProfiles PS51340 MOSC domain profile. 589 740 24.79300
12 g12792.t1 SUPERFAMILY SSF53383 PLP-dependent transferases 11 438 0.00000
14 g12792.t1 SUPERFAMILY SSF141673 MOSC N-terminal domain-like 463 598 0.00000
11 g12792.t1 SUPERFAMILY SSF53383 PLP-dependent transferases 729 1143 0.00000
13 g12792.t1 SUPERFAMILY SSF141673 MOSC N-terminal domain-like 1178 1270 0.00000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006777 Mo-molybdopterin cofactor biosynthetic process BP
GO:0008265 Mo-molybdopterin cofactor sulfurase activity MF
GO:0030151 molybdenum ion binding MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values