Gene loci information

Transcript annotation

  • This transcript has been annotated as Molybdenum cofactor sulfurase 3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12792 g12792.t2 TTS g12792.t2 26223894 26223894
chr_1 g12792 g12792.t2 isoform g12792.t2 26223977 26225946
chr_1 g12792 g12792.t2 exon g12792.t2.exon1 26223977 26225946
chr_1 g12792 g12792.t2 cds g12792.t2.CDS1 26223978 26225744
chr_1 g12792 g12792.t2 TSS g12792.t2 26226646 26226646

Sequences

>g12792.t2 Gene=g12792 Length=1970
AGTGCTTAAACACTTCAATGCTGACCCAGATGAATATTCAATTATTTTTACATCGGGTTG
CACAGCTGCACTTAAAATTGTTGGTGAATGTTTCCAATTTGGTGATAATGGTGCCTTTTA
TTATCTCACTGATTCTCACACATCAGTTTTGGGTCTTCGAGAAATTGTTCAGACTGACAA
AATTATTCCTGTTTCTGAGACAATGCTAAGTGTTATCAACATGATGCATGGAGGAACTTC
ATTGCTTGTTTTTCCAGCTCAATGCAATTATAATGGACAAAAATATTCACTAGATATAAT
TAAAAAAGTTCATGAAAATCCAAACATGTTTGTTCTGCTTGATGCTGCTGCTTTTGTATC
AACAAACAAGCTTGATTTGAGTATTTATAAACCAAATTATGTCGCTCTTTCATTCTACAA
AATTTTTGGCACTCCAACTGGTCTCGGTGCTTTGATTATTTCAAAAAGAGGAGCTGAAAA
CTTAAATAAAAAGTATTATGGAGGTGGAACTGTCAAAATTGCATTAACACGTGAAAATTG
GCATGAAAAGCGTGATGGAATTTCTGAAAAATTTGAAGATGGAACACCAAATTTTCAAGG
AATTTTGAGTCTTCACACATCATTTAAATATTTTGAAAATTTACTTGGCGACGAATTTAT
TGAAAGAATTTCAAGGCATGTTTTTAATTTGGGAAAATATTTCTATCATTATATGAAGAG
TTTTAAGCATTACAATCAACAACCAGTGACAATTTTCTATCATAATTCTGATTTTGATGA
TATTCAAACTCAAGGTGGTGTTGTGACATTCAATTTAAAACGACCTGATGGATCTTTTGT
TGGTTTTGCTGAATTTGCCAGTATTGCAGCACTTCATAATATCATAATTAGAACAGGTTG
CTTTTGCAATCCTGGAGCCTGTCAAACGCACTTGAAGTTAACAAATAAAGATTTAAAGAA
GCACTTTGATGCCGGTCATGTGTGTGGTGATTTGAATGATTTAGTTGATGGAATACCCAC
AGGCTGTATTCGAGTTTCATTTGGATACATGAATACAAAAGAAGATGTCGATAAATTACT
GAAAATCGTTGAATCTTGTTATGTTCAAAAAGTCGAGAATTTTGAAATTGATAAACCAAA
AGAAATACTTAATGGTGAATCAAAAGCAATTTTGAAATCAATAAGAATTTACCCAATAAA
ATCATGTGGAGCAATGAAAATTGACACTGAATGGCCACTCTCACGAACAGGTTTAAAATA
TGATCGTGAATGGATGATAATGAATGGAAACAATGGAACATCATTAACTCAAAAGAATGA
GCCAAAAATGTGCATGATTTGGCCATACATTGATGAAAGCAAAAACACATTACGGCTCGA
TTTTCCGCATTCTAATTCAATAGAAGTTTTACTAAATGACAACAAAACCGGAGGAAAGCA
ATTAGAAGCTTCTATTTGTGAAACAAAAGTGTGTGGTGATCGAATAAATGGAATTGATTG
TGGTGATGAAGTAGCAAAATGGCTTAGTGATGTTCTTATGATGGAAAATTTACGGTTGAT
TAGGCAAATTAATCAAAATGAGAGGAAAAATGGAAAAGAAATTGCATTGGCAAATCAAGC
GCAATTTCTTCTTATTAGTGAAGCATCAGTTCAATGGCTTATGAATCAAGTTGAAAGTTG
GGACAATGATGAGAAAAATATGGAAAATGTTATCGATAGATTTCGTGGAAACTTCATAAT
TGAAAACCTTGAAGCATTGGCTGAAAATAATTGGAAATGTTTGAAAATTGGTGATGAAAA
TACTTTTCATATCGAAGGTCCATGCACTCGATGTCAGATGATTTGTATTGATCAAAATAC
AGGAGAAAAAACTACTGAACCATTAAGAACGATGGGAAAAGTTTTTAATGGAAAAACTAA
ATTTGGAATTTATTTAAAAATGTTGAAAAATTCGAGCGTGATAAGATGTG

>g12792.t2 Gene=g12792 Length=589
MLSVINMMHGGTSLLVFPAQCNYNGQKYSLDIIKKVHENPNMFVLLDAAAFVSTNKLDLS
IYKPNYVALSFYKIFGTPTGLGALIISKRGAENLNKKYYGGGTVKIALTRENWHEKRDGI
SEKFEDGTPNFQGILSLHTSFKYFENLLGDEFIERISRHVFNLGKYFYHYMKSFKHYNQQ
PVTIFYHNSDFDDIQTQGGVVTFNLKRPDGSFVGFAEFASIAALHNIIIRTGCFCNPGAC
QTHLKLTNKDLKKHFDAGHVCGDLNDLVDGIPTGCIRVSFGYMNTKEDVDKLLKIVESCY
VQKVENFEIDKPKEILNGESKAILKSIRIYPIKSCGAMKIDTEWPLSRTGLKYDREWMIM
NGNNGTSLTQKNEPKMCMIWPYIDESKNTLRLDFPHSNSIEVLLNDNKTGGKQLEASICE
TKVCGDRINGIDCGDEVAKWLSDVLMMENLRLIRQINQNERKNGKEIALANQAQFLLISE
ASVQWLMNQVESWDNDEKNMENVIDRFRGNFIIENLEALAENNWKCLKIGDENTFHIEGP
CTRCQMICIDQNTGEKTTEPLRTMGKVFNGKTKFGIYLKMLKNSSVIRC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g12792.t2 Gene3D G3DSA:3.40.640.10 - 3 143 3.1E-28
8 g12792.t2 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 144 303 4.3E-23
4 g12792.t2 PANTHER PTHR14237:SF67 MOLYBDENUM COFACTOR SULFURASE 14 566 2.1E-86
5 g12792.t2 PANTHER PTHR14237 MOLYBDOPTERIN COFACTOR SULFURASE MOSC 14 566 2.1E-86
3 g12792.t2 Pfam PF00266 Aminotransferase class-V 30 292 2.1E-21
2 g12792.t2 Pfam PF03476 MOSC N-terminal beta barrel domain 323 446 2.3E-26
1 g12792.t2 Pfam PF03473 MOSC domain 466 586 3.9E-23
12 g12792.t2 Phobius SIGNAL_PEPTIDE Signal peptide region 1 21 -
13 g12792.t2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 9 -
14 g12792.t2 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 10 17 -
15 g12792.t2 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 18 21 -
11 g12792.t2 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 22 589 -
10 g12792.t2 ProSiteProfiles PS51340 MOSC domain profile. 450 589 27.746
6 g12792.t2 SUPERFAMILY SSF53383 PLP-dependent transferases 6 299 2.59E-39
7 g12792.t2 SUPERFAMILY SSF141673 MOSC N-terminal domain-like 324 459 5.75E-31

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0030151 molybdenum ion binding MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values