General information for g12792.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Molybdenum cofactor sulfurase 3.
Parent gene
- The parent gene g12792 is located on chr_1: 26223977..26226528 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12792 | g12792.t3 | TTS | g12792.t3 | 26223894 | 26223894 |
| chr_1 | g12792 | g12792.t3 | isoform | g12792.t3 | 26223977 | 26226528 |
| chr_1 | g12792 | g12792.t3 | exon | g12792.t3.exon1 | 26223977 | 26225946 |
| chr_1 | g12792 | g12792.t3 | cds | g12792.t3.CDS1 | 26223978 | 26225946 |
| chr_1 | g12792 | g12792.t3 | exon | g12792.t3.exon2 | 26226006 | 26226150 |
| chr_1 | g12792 | g12792.t3 | cds | g12792.t3.CDS2 | 26226006 | 26226150 |
| chr_1 | g12792 | g12792.t3 | exon | g12792.t3.exon3 | 26226459 | 26226528 |
| chr_1 | g12792 | g12792.t3 | cds | g12792.t3.CDS3 | 26226459 | 26226528 |
| chr_1 | g12792 | g12792.t3 | TSS | g12792.t3 | 26226646 | 26226646 |
Sequences
>g12792.t3 Gene=g12792 Length=2185
ATGGATTTTATTAACGAATTTAATGAGAAAGAGATTGAAAAGATTAAAAGTGATTTTACA
AGATTAAAAGACACAACATATCTTGATACAACAGGAGCAGCACTTTATGGAGAAAGTCAA
ATGCGAGAAGTTTGTCAAGTATTGACTTCAAATCTAATCAGTAGTCCACACACATCAAAG
GCAACTGGAAATATTATTGATCAAGTTCGTTATAGAGTGCTTAAACACTTCAATGCTGAC
CCAGATGAATATTCAATTATTTTTACATCGGGTTGCACAGCTGCACTTAAAATTGTTGGT
GAATGTTTCCAATTTGGTGATAATGGTGCCTTTTATTATCTCACTGATTCTCACACATCA
GTTTTGGGTCTTCGAGAAATTGTTCAGACTGACAAAATTATTCCTGTTTCTGAGACAATG
CTAAGTGTTATCAACATGATGCATGGAGGAACTTCATTGCTTGTTTTTCCAGCTCAATGC
AATTATAATGGACAAAAATATTCACTAGATATAATTAAAAAAGTTCATGAAAATCCAAAC
ATGTTTGTTCTGCTTGATGCTGCTGCTTTTGTATCAACAAACAAGCTTGATTTGAGTATT
TATAAACCAAATTATGTCGCTCTTTCATTCTACAAAATTTTTGGCACTCCAACTGGTCTC
GGTGCTTTGATTATTTCAAAAAGAGGAGCTGAAAACTTAAATAAAAAGTATTATGGAGGT
GGAACTGTCAAAATTGCATTAACACGTGAAAATTGGCATGAAAAGCGTGATGGAATTTCT
GAAAAATTTGAAGATGGAACACCAAATTTTCAAGGAATTTTGAGTCTTCACACATCATTT
AAATATTTTGAAAATTTACTTGGCGACGAATTTATTGAAAGAATTTCAAGGCATGTTTTT
AATTTGGGAAAATATTTCTATCATTATATGAAGAGTTTTAAGCATTACAATCAACAACCA
GTGACAATTTTCTATCATAATTCTGATTTTGATGATATTCAAACTCAAGGTGGTGTTGTG
ACATTCAATTTAAAACGACCTGATGGATCTTTTGTTGGTTTTGCTGAATTTGCCAGTATT
GCAGCACTTCATAATATCATAATTAGAACAGGTTGCTTTTGCAATCCTGGAGCCTGTCAA
ACGCACTTGAAGTTAACAAATAAAGATTTAAAGAAGCACTTTGATGCCGGTCATGTGTGT
GGTGATTTGAATGATTTAGTTGATGGAATACCCACAGGCTGTATTCGAGTTTCATTTGGA
TACATGAATACAAAAGAAGATGTCGATAAATTACTGAAAATCGTTGAATCTTGTTATGTT
CAAAAAGTCGAGAATTTTGAAATTGATAAACCAAAAGAAATACTTAATGGTGAATCAAAA
GCAATTTTGAAATCAATAAGAATTTACCCAATAAAATCATGTGGAGCAATGAAAATTGAC
ACTGAATGGCCACTCTCACGAACAGGTTTAAAATATGATCGTGAATGGATGATAATGAAT
GGAAACAATGGAACATCATTAACTCAAAAGAATGAGCCAAAAATGTGCATGATTTGGCCA
TACATTGATGAAAGCAAAAACACATTACGGCTCGATTTTCCGCATTCTAATTCAATAGAA
GTTTTACTAAATGACAACAAAACCGGAGGAAAGCAATTAGAAGCTTCTATTTGTGAAACA
AAAGTGTGTGGTGATCGAATAAATGGAATTGATTGTGGTGATGAAGTAGCAAAATGGCTT
AGTGATGTTCTTATGATGGAAAATTTACGGTTGATTAGGCAAATTAATCAAAATGAGAGG
AAAAATGGAAAAGAAATTGCATTGGCAAATCAAGCGCAATTTCTTCTTATTAGTGAAGCA
TCAGTTCAATGGCTTATGAATCAAGTTGAAAGTTGGGACAATGATGAGAAAAATATGGAA
AATGTTATCGATAGATTTCGTGGAAACTTCATAATTGAAAACCTTGAAGCATTGGCTGAA
AATAATTGGAAATGTTTGAAAATTGGTGATGAAAATACTTTTCATATCGAAGGTCCATGC
ACTCGATGTCAGATGATTTGTATTGATCAAAATACAGGAGAAAAAACTACTGAACCATTA
AGAACGATGGGAAAAGTTTTTAATGGAAAAACTAAATTTGGAATTTATTTAAAAATGTTG
AAAAATTCGAGCGTGATAAGATGTG
>g12792.t3 Gene=g12792 Length=728
MDFINEFNEKEIEKIKSDFTRLKDTTYLDTTGAALYGESQMREVCQVLTSNLISSPHTSK
ATGNIIDQVRYRVLKHFNADPDEYSIIFTSGCTAALKIVGECFQFGDNGAFYYLTDSHTS
VLGLREIVQTDKIIPVSETMLSVINMMHGGTSLLVFPAQCNYNGQKYSLDIIKKVHENPN
MFVLLDAAAFVSTNKLDLSIYKPNYVALSFYKIFGTPTGLGALIISKRGAENLNKKYYGG
GTVKIALTRENWHEKRDGISEKFEDGTPNFQGILSLHTSFKYFENLLGDEFIERISRHVF
NLGKYFYHYMKSFKHYNQQPVTIFYHNSDFDDIQTQGGVVTFNLKRPDGSFVGFAEFASI
AALHNIIIRTGCFCNPGACQTHLKLTNKDLKKHFDAGHVCGDLNDLVDGIPTGCIRVSFG
YMNTKEDVDKLLKIVESCYVQKVENFEIDKPKEILNGESKAILKSIRIYPIKSCGAMKID
TEWPLSRTGLKYDREWMIMNGNNGTSLTQKNEPKMCMIWPYIDESKNTLRLDFPHSNSIE
VLLNDNKTGGKQLEASICETKVCGDRINGIDCGDEVAKWLSDVLMMENLRLIRQINQNER
KNGKEIALANQAQFLLISEASVQWLMNQVESWDNDEKNMENVIDRFRGNFIIENLEALAE
NNWKCLKIGDENTFHIEGPCTRCQMICIDQNTGEKTTEPLRTMGKVFNGKTKFGIYLKML
KNSSVIRC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g12792.t3 | Gene3D | G3DSA:3.40.640.10 | - | 40 | 283 | 0.00000 |
| 9 | g12792.t3 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 284 | 441 | 0.00000 |
| 6 | g12792.t3 | Hamap | MF_03050 | Molybdenum cofactor sulfurase [MOCOS]. | 6 | 728 | 20.93422 |
| 4 | g12792.t3 | PANTHER | PTHR14237:SF67 | MOLYBDENUM COFACTOR SULFURASE | 11 | 705 | 0.00000 |
| 5 | g12792.t3 | PANTHER | PTHR14237 | MOLYBDOPTERIN COFACTOR SULFURASE MOSC | 11 | 705 | 0.00000 |
| 3 | g12792.t3 | Pfam | PF00266 | Aminotransferase class-V | 39 | 431 | 0.00000 |
| 2 | g12792.t3 | Pfam | PF03476 | MOSC N-terminal beta barrel domain | 462 | 585 | 0.00000 |
| 1 | g12792.t3 | Pfam | PF03473 | MOSC domain | 605 | 725 | 0.00000 |
| 11 | g12792.t3 | ProSiteProfiles | PS51340 | MOSC domain profile. | 589 | 728 | 27.74600 |
| 7 | g12792.t3 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 11 | 438 | 0.00000 |
| 8 | g12792.t3 | SUPERFAMILY | SSF141673 | MOSC N-terminal domain-like | 463 | 598 | 0.00000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006777 | Mo-molybdopterin cofactor biosynthetic process | BP |
| GO:0008265 | Mo-molybdopterin cofactor sulfurase activity | MF |
| GO:0030151 | molybdenum ion binding | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K15631 (molybdenum cofactor sulfurtransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
