General information for g13028.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative aldehyde dehydrogenase family 7 member A1-like protein.
Parent gene
- The parent gene g13028 is located on chr_1: 27589461..27590538 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13028 | g13028.t1 | TTS | g13028.t1 | 27588380 | 27588380 |
| chr_1 | g13028 | g13028.t1 | isoform | g13028.t1 | 27588420 | 27590211 |
| chr_1 | g13028 | g13028.t1 | exon | g13028.t1.exon1 | 27588420 | 27588574 |
| chr_1 | g13028 | g13028.t1 | cds | g13028.t1.CDS1 | 27588420 | 27588574 |
| chr_1 | g13028 | g13028.t1 | exon | g13028.t1.exon2 | 27588629 | 27588865 |
| chr_1 | g13028 | g13028.t1 | cds | g13028.t1.CDS2 | 27588629 | 27588865 |
| chr_1 | g13028 | g13028.t1 | exon | g13028.t1.exon3 | 27588930 | 27589095 |
| chr_1 | g13028 | g13028.t1 | cds | g13028.t1.CDS3 | 27588930 | 27589095 |
| chr_1 | g13028 | g13028.t1 | exon | g13028.t1.exon4 | 27589156 | 27590211 |
| chr_1 | g13028 | g13028.t1 | cds | g13028.t1.CDS4 | 27589156 | 27590211 |
| chr_1 | g13028 | g13028.t1 | TSS | g13028.t1 | 27590232 | 27590232 |
Sequences
>g13028.t1 Gene=g13028 Length=1614
ATGATCAGCTCTATAATTCGTTGTAGTGCACTTAAAGTGAATAAATTTTTGTATTTGTCT
TATAGAGCAATGTCATCGTCACGTTATCTCATTGATGATCCAAATTTTTCTTTCCTAAAA
GAGCTCGGATTAGAACGAGTAAACAAAGGAGTTTATAATGGCGAATGGTGCGGTAGTGGT
GAGCTATCAAAATCTATTGATCCAGCAACAAACGAGGTTATCGCTGAAGTTCAAAATGGA
AGTGTTGATGATCTTGAAAGTTGCATAAAAACAGCTGAAGATGCATACAAACATTGGAGA
AATATGCCAGCTCCATTTAGAGGTGAAATTGTGAGACAAATTGGTGATGAATTGAGAAAA
TATCGTGAACCACTTGGTAAACTTGTTTCACTCGAAATGGGAAAAATTCAAGCTGAAGGG
ATTGGTGAAGTTCAGGAGTTTATCGACATTTGTGACTACGCAACTGGCTTATCACGAATG
TTTGCTGGTCAAATCTTACCATCAGAACGCAATCAACATGTGATTATTGAAAAATGGAAT
CCACTTGGAATTGTTGGTATCATTTCAGCATTTAATTTTCCTAATGCAGTCTTTGGATGG
AATGCTGCTATTGCTTTAGCAGTGGGAAATGTCTCTCTATGGAAAGGTGCACCATCAACT
CCTCTTGTATCAATTGCAACAACAAAAATTGTCACTGAAGTCCTTAAACGCAATAATTTA
CCACCGACTATTACTTTATGCCAAGGAGGAACTGAAGTTGGTAAAAAATTAGTTGCTGAT
AAACGTGTGAAACTTGTTTCATTCACTGGCAGTTCAAAAGTCGGTCAAGAAGTTGGTGTT
GAAGTACAAAAGAGATTTGGTAAATTGATTCTTGAATTAGGTGGCAACAATGCACTCATT
ATTAATGATGATGCCGATTTTGATATGGCACTTGATGCTGCATTCTTTGGATGTATTGGA
ACAGCTGGACAAAGATGCACAACAACAAGAAGATTGATTATTCATGAAAAACTTTATGAT
GCTTTCTTACAGAAATTAATTGCAAGATATAAAGGACTTATGAAACGTGTCGGTCATCCA
TTAGATTCATCAACGCTTTATGGTCCACTTCATAATCAACAAGCTGTTGATAATTATAAA
GCAACTATCGATGAAGCAGTTAAGCTTGGTGGAAAAATTGAAGTAGGAGGAAATGTGATG
GAAAGACCAGGATTCTTTGTTGAACCAACAATTGTTACAAATTTACTTCATGATTCACCA
ATCATTATGAGAGAAACTTTCGCACCAATTGTCTATGTTTTAAAAGCTAAAAATTTAGAA
CAAGCCATTGAATGGAATAATGAAGTTGATCAAGGACTTTCATCTGCACTCTTTACAAAA
AATCTTGGTTCAACATTCAAATGGATAACTGAAAATGGAAGTGATTGTGGAATTGTTAAT
ATTAATACATCTCCATCAGGTGCTGAAATCGGTGGTGCATTCGGTGGAGAAAAGCACACA
GGTGGTGGTCGTGAAAGTGGATCAGATTCATGGAAACAATATTGTCGTCGATCGACAATC
ACATTGAATTACTCTCAACAATTACCACTCGCACAAGGAATTATTTTTGAATAA
>g13028.t1 Gene=g13028 Length=537
MISSIIRCSALKVNKFLYLSYRAMSSSRYLIDDPNFSFLKELGLERVNKGVYNGEWCGSG
ELSKSIDPATNEVIAEVQNGSVDDLESCIKTAEDAYKHWRNMPAPFRGEIVRQIGDELRK
YREPLGKLVSLEMGKIQAEGIGEVQEFIDICDYATGLSRMFAGQILPSERNQHVIIEKWN
PLGIVGIISAFNFPNAVFGWNAAIALAVGNVSLWKGAPSTPLVSIATTKIVTEVLKRNNL
PPTITLCQGGTEVGKKLVADKRVKLVSFTGSSKVGQEVGVEVQKRFGKLILELGGNNALI
INDDADFDMALDAAFFGCIGTAGQRCTTTRRLIIHEKLYDAFLQKLIARYKGLMKRVGHP
LDSSTLYGPLHNQQAVDNYKATIDEAVKLGGKIEVGGNVMERPGFFVEPTIVTNLLHDSP
IIMRETFAPIVYVLKAKNLEQAIEWNNEVDQGLSSALFTKNLGSTFKWITENGSDCGIVN
INTSPSGAEIGGAFGGEKHTGGGRESGSDSWKQYCRRSTITLNYSQQLPLAQGIIFE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g13028.t1 | CDD | cd07130 | ALDH_F7_AASADH | 50 | 525 | 0.0 |
| 6 | g13028.t1 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 61 | 514 | 1.7E-145 |
| 7 | g13028.t1 | Gene3D | G3DSA:3.40.309.10 | Aldehyde Dehydrogenase; Chain A | 295 | 489 | 1.7E-145 |
| 2 | g13028.t1 | PANTHER | PTHR43521:SF1 | ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE | 46 | 534 | 2.2E-224 |
| 3 | g13028.t1 | PANTHER | PTHR43521 | ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE | 46 | 534 | 2.2E-224 |
| 1 | g13028.t1 | Pfam | PF00171 | Aldehyde dehydrogenase family | 63 | 519 | 1.1E-130 |
| 5 | g13028.t1 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 291 | 298 | - |
| 4 | g13028.t1 | SUPERFAMILY | SSF53720 | ALDH-like | 48 | 526 | 2.09E-129 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14085 (aldehyde dehydrogenase family 7 member A1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
