Gene loci information

Transcript annotation

  • This transcript has been annotated as Vinculin.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13030 g13030.t3 isoform g13030.t3 27591873 27594146
chr_1 g13030 g13030.t3 exon g13030.t3.exon1 27591873 27592492
chr_1 g13030 g13030.t3 cds g13030.t3.CDS1 27592429 27592492
chr_1 g13030 g13030.t3 exon g13030.t3.exon2 27593369 27593463
chr_1 g13030 g13030.t3 cds g13030.t3.CDS2 27593369 27593463
chr_1 g13030 g13030.t3 exon g13030.t3.exon3 27593520 27594146
chr_1 g13030 g13030.t3 cds g13030.t3.CDS3 27593520 27593945
chr_1 g13030 g13030.t3 TSS g13030.t3 NA NA
chr_1 g13030 g13030.t3 TTS g13030.t3 NA NA

Sequences

>g13030.t3 Gene=g13030 Length=1342
TTGCTTCAAAATGTCCGAAATGTTCGTAATGCAATCACACAACAACCAGAAATCCCAGCA
CCACCAGATCTTTCAGCACTTCGACTTAATGCAGAATCGCATGTTCCGCCACCAAGACCA
CCATTGCCACGTGAAGAAATTCCACCAGTTCGTCCTCCACCACCTGAAACTGATGATGAA
GATGAAGGCGTTTTCAAGGCAATGCCAACATCTAATCAACCAATTTTGCTTGCCGCTCAT
GGACTTCATCAAGAAGTTCGTCAATGGTCATCAAAGGACAATGAAATTATTGCAGCTGCT
AAACGTATGGCTGTTTTAATGGCTCGCTTGTCAGAACTTGTTCATCAAGACTCGAAAGGA
AGCAAACGTGAATTGATTGCCACTGCCAAATTAATTGCCGAAGCATCAGAAGATGTAACA
CGTATTGCTAAGGCATTGGCTAGAGAATGTACTGACAAGAGAATTAGAACAAATTTGCTA
CAAGTTTGTGAAAGAATACCAACAATTGGAACACAACTTAAAATTTTGTCAACAGTCAAA
GCAACAATGTTGGGTGCTCAAGGAAGCGATGAAGACCGTGAAGCAACAGAAATGCTTGTT
GGAAATGCTCAAAATCTCATGCAAAGCGTGAAAGAGACAGTTCGTGCCGCAGAAGGTGCT
AGTATTAAGATAAGAAGCGATCAAACAAATCATCGTCTGAGATGGATTCGTAGACAACCC
TGGCATGAGAGAATCGATCTTTCTGACGGAACCCGAGATATAATTGAGTATAAGCAATCG
TACTAAAATGTATGTGCCAAAGTATGATGAGTCGTACTTATCATTAAAAATCAAACAAAA
AATATATATTCAAAAATTTTATGATAAATTTAAAAAAATAAACACACTTGTTGATTCTAA
TGTGAATAAGCAATGTGCAGCAGCTAAGATTAAAACACATCGAGTGTTTACTAAATAAAT
TTATTTTAACAGACAAATTTTTATTTGTTTTCTCCTCTTCTCTACATTATTAATAAAATG
AATTACAAATTAAACTTAGAAATGATGAATAAAATTTAACTTTACGGTGACATTGTTGTT
GAAATTAAATGTAATGAAAAAAAAACAATCAAAAAAATTTATAGAAACTTTATGGCTTTA
GGATTGTTTAAAAAAACATGAAAAATGAACATTTTTCTTCGTCCCTTAATAATAAACATT
AACTTTTTTTGTGTACACTAAATAGTTCTAATAGGTTCGAAACAAATTAAAAATGATGTT
TTTTGAAGGTAAAAAGTTAAATAAATAAAAATCTTTTAAAAATTTAATAAAAATTTGACT
TTTATTCATAATCACATAATCT

>g13030.t3 Gene=g13030 Length=194
MPTSNQPILLAAHGLHQEVRQWSSKDNEIIAAAKRMAVLMARLSELVHQDSKGSKRELIA
TAKLIAEASEDVTRIAKALARECTDKRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQ
GSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTNHRLRWIRRQPWHERIDL
SDGTRDIIEYKQSY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g13030.t3 Gene3D G3DSA:1.20.120.230 - 1 176 0
2 g13030.t3 PANTHER PTHR46180:SF1 VINCULIN 3 175 0
3 g13030.t3 PANTHER PTHR46180 VINCULIN 3 175 0
6 g13030.t3 PRINTS PR00806 Vinculin signature 27 44 0
5 g13030.t3 PRINTS PR00806 Vinculin signature 63 78 0
7 g13030.t3 PRINTS PR00806 Vinculin signature 78 93 0
4 g13030.t3 PRINTS PR00806 Vinculin signature 97 118 0
8 g13030.t3 PRINTS PR00806 Vinculin signature 132 151 0
1 g13030.t3 Pfam PF01044 Vinculin family 4 175 0
9 g13030.t3 SUPERFAMILY SSF47220 alpha-catenin/vinculin-like 4 170 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0051015 actin filament binding MF
GO:0003779 actin binding MF
GO:0007155 cell adhesion BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values