Gene loci information

Transcript annotation

  • This transcript has been annotated as Aspartate aminotransferase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13095 g13095.t10 TSS g13095.t10 27932619 27932619
chr_1 g13095 g13095.t10 isoform g13095.t10 27933244 27934520
chr_1 g13095 g13095.t10 exon g13095.t10.exon1 27933244 27933646
chr_1 g13095 g13095.t10 exon g13095.t10.exon2 27933765 27934253
chr_1 g13095 g13095.t10 cds g13095.t10.CDS1 27933897 27934253
chr_1 g13095 g13095.t10 exon g13095.t10.exon3 27934314 27934520
chr_1 g13095 g13095.t10 cds g13095.t10.CDS2 27934314 27934520
chr_1 g13095 g13095.t10 TTS g13095.t10 27934761 27934761

Sequences

>g13095.t10 Gene=g13095 Length=1099
AGGCGCTTATCGCGATGATAATGGAAAACCTTATGTTTTACCTAGCGTTCAAAAGGCCGA
AGAATTATTGGCAAAGAAAGCTTTAGATAAAGAATATGCCCCGATTTCTGGACCTGCTGA
CTTTTGTAAATTGAGTATTGAATTGGCATTGGGAGAAAGTGAAGAACTCAAAGCCGGATT
GAATGCTACAGTTCAAGGAATTTCAGGAACTGGCTCATTGCGTGTTGGCGGCGCTTTCTT
GGCAAGTTTCTTCCCTGGACCTAAAGAAATTTATCTGCCAACACCATCATGGGGTAATCA
TACACCAATTTTCAAACACTCAGGACTTGGTGTTAAACAGTACAAATATTACGATCCAAA
AACATGTGGCTTAGACTTTCAAGGAGCTCTGGACGACATTTCCAAAATCCCTGAACGTTC
AATTATTTTGCTTCACGCTTGTGCTCATAATCCTACTGGTGTAGACCCAACGCCAGAACA
ATGGCAAGAGTTATCGGCATTAATTAAGAAAAAGAATTTATTCCCGTACTTTGATATGGC
TTATCAAGGATTCGCTAGTGGATCAGTTGATAAAGATGCATTTGCTGTTCGATTGTTTAT
TCGTGATGGACATCAAATTGCTTTGGCTCAAAGTTATGCAAAGAACATGGGTCTTTATGG
AGAACGCGCTGGTGCATTTTCACTCATTACAAGTAGTAAAGATGAGGCTGAACGTACATT
ATCACAACTTAAGATTCTCATTAGACCAATGTATTCGAATCCACCCATTCATGGTGCACG
TATTGTTAGCACAATTTTAAGTACACCCGATTTGAGATCAGAATGGTTGAAAGATGTAAA
AGGAATGGCTGATCGTATTATTTCTGTTCGAGCAACATTGAGAAAGAATTTGGAAAATCT
TGGATCAAAGAAGAATTGGCAACACATTACCGATCAAATCGGTATGTTCTGTTTCACTGG
AATGAATGCAGATCAAAGTACTCGTTTGTGCAACGAATTCAGCATCTATTTGACAAAAGA
TGGAAGAATTTCAATGGCTGGTGTCACTTCAAAGAATGTTGAATACTTGGCTCATGGAAT
TCATGAAGTCACAAAGTAA

>g13095.t10 Gene=g13095 Length=187
MAYQGFASGSVDKDAFAVRLFIRDGHQIALAQSYAKNMGLYGERAGAFSLITSSKDEAER
TLSQLKILIRPMYSNPPIHGARIVSTILSTPDLRSEWLKDVKGMADRIISVRATLRKNLE
NLGSKKNWQHITDQIGMFCFTGMNADQSTRLCNEFSIYLTKDGRISMAGVTSKNVEYLAH
GIHEVTK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g13095.t10 Gene3D G3DSA:3.40.640.10 - 1 85 5.8E-30
7 g13095.t10 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 86 187 4.2E-38
2 g13095.t10 PANTHER PTHR11879 ASPARTATE AMINOTRANSFERASE 1 186 1.6E-87
3 g13095.t10 PRINTS PR00799 Aspartate aminotransferase signature 63 88 4.8E-18
4 g13095.t10 PRINTS PR00799 Aspartate aminotransferase signature 131 149 4.8E-18
1 g13095.t10 Pfam PF00155 Aminotransferase class I and II 1 181 1.6E-37
6 g13095.t10 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 33 46 -
5 g13095.t10 SUPERFAMILY SSF53383 PLP-dependent transferases 1 186 1.09E-48

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009058 biosynthetic process BP
GO:0006520 cellular amino acid metabolic process BP
GO:0008483 transaminase activity MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values