Gene loci information

Transcript annotation

  • This transcript has been annotated as Aspartate aminotransferase, mitochondrial.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13095 g13095.t8 TSS g13095.t8 27932619 27932619
chr_1 g13095 g13095.t8 isoform g13095.t8 27932662 27934520
chr_1 g13095 g13095.t8 exon g13095.t8.exon1 27932662 27933115
chr_1 g13095 g13095.t8 cds g13095.t8.CDS1 27933034 27933115
chr_1 g13095 g13095.t8 exon g13095.t8.exon2 27933246 27933646
chr_1 g13095 g13095.t8 cds g13095.t8.CDS2 27933246 27933646
chr_1 g13095 g13095.t8 exon g13095.t8.exon3 27933765 27934253
chr_1 g13095 g13095.t8 cds g13095.t8.CDS3 27933765 27934253
chr_1 g13095 g13095.t8 exon g13095.t8.exon4 27934314 27934520
chr_1 g13095 g13095.t8 cds g13095.t8.CDS4 27934314 27934520
chr_1 g13095 g13095.t8 TTS g13095.t8 27934761 27934761

Sequences

>g13095.t8 Gene=g13095 Length=1551
ATGTCTTCTAAACTTTTGCAAAATAAAGGGTTGACAAGTATTTTAGCAACGAGATGCAGG
TAAACCGGGAATAAATACAGAAAATTTTTCTCCATTCATACAAGTTTTCCATATTCTTGT
GACCTCTCAATGACATGGAGCCTTTTTATAAATTTCTTTGATTAATTGCTGTTAATAAAC
GCATAAAAATGCAAATGAAATGTGTTAATGATAAGATCACAAAAAATTATTATATTAAAT
GCTTCAAAAAATTGAGAATGTGAATCACTCATTTGCCACATGATAATTGCCTTTTCCTTC
ATAATTGTCTTTTCTGTTCTGTTATCTAATCATTATAAACATATTAACAGCTCATGGTGG
AGTTCTGTTCAAATGGGACCACCTGATGCAATTCTCGGTGTTACAGAAGCATTTAAAAAG
GATACAAATCCTAAGAAGATCAACTTGGGTGTCGGCGCTTATCGCGATGATAATGGAAAA
CCTTATGTTTTACCTAGCGTTCAAAAGGCCGAAGAATTATTGGCAAAGAAAGCTTTAGAT
AAAGAATATGCCCCGATTTCTGGACCTGCTGACTTTTGTAAATTGAGTATTGAATTGGCA
TTGGGAGAAAGTGAAGAACTCAAAGCCGGATTGAATGCTACAGTTCAAGGAATTTCAGGA
ACTGGCTCATTGCGTGTTGGCGGCGCTTTCTTGGCAAGTTTCTTCCCTGGACCTAAAGAA
ATTTATCTGCCAACACCATCATGGGGTAATCATACACCAATTTTCAAACACTCAGGACTT
GGTGTTAAACAGTACAAATATTACGATCCAAAAACATGTGGCTTAGACTTTCAAGGAGCT
CTGGACGACATTTCCAAAATCCCTGAACGTTCAATTATTTTGCTTCACGCTTGTGCTCAT
AATCCTACTGGTGTAGACCCAACGCCAGAACAATGGCAAGAGTTATCGGCATTAATTAAG
AAAAAGAATTTATTCCCGTACTTTGATATGGCTTATCAAGGATTCGCTAGTGGATCAGTT
GATAAAGATGCATTTGCTGTTCGATTGTTTATTCGTGATGGACATCAAATTGCTTTGGCT
CAAAGTTATGCAAAGAACATGGGTCTTTATGGAGAACGCGCTGGTGCATTTTCACTCATT
ACAAGTAGTAAAGATGAGGCTGAACGTACATTATCACAACTTAAGATTCTCATTAGACCA
ATGTATTCGAATCCACCCATTCATGGTGCACGTATTGTTAGCACAATTTTAAGTACACCC
GATTTGAGATCAGAATGGTTGAAAGATGTAAAAGGAATGGCTGATCGTATTATTTCTGTT
CGAGCAACATTGAGAAAGAATTTGGAAAATCTTGGATCAAAGAAGAATTGGCAACACATT
ACCGATCAAATCGGTATGTTCTGTTTCACTGGAATGAATGCAGATCAAAGTACTCGTTTG
TGCAACGAATTCAGCATCTATTTGACAAAAGATGGAAGAATTTCAATGGCTGGTGTCACT
TCAAAGAATGTTGAATACTTGGCTCATGGAATTCATGAAGTCACAAAGTAA

>g13095.t8 Gene=g13095 Length=392
MGPPDAILGVTEAFKKDTNPKKINLGVGAYRDDNGKPYVLPSVQKAEELLAKKALDKEYA
PISGPADFCKLSIELALGESEELKAGLNATVQGISGTGSLRVGGAFLASFFPGPKEIYLP
TPSWGNHTPIFKHSGLGVKQYKYYDPKTCGLDFQGALDDISKIPERSIILLHACAHNPTG
VDPTPEQWQELSALIKKKNLFPYFDMAYQGFASGSVDKDAFAVRLFIRDGHQIALAQSYA
KNMGLYGERAGAFSLITSSKDEAERTLSQLKILIRPMYSNPPIHGARIVSTILSTPDLRS
EWLKDVKGMADRIISVRATLRKNLENLGSKKNWQHITDQIGMFCFTGMNADQSTRLCNEF
SIYLTKDGRISMAGVTSKNVEYLAHGIHEVTK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g13095.t8 CDD cd00609 AAT_like 23 381 2.22791E-42
10 g13095.t8 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 5 388 1.1E-171
11 g13095.t8 Gene3D G3DSA:3.40.640.10 - 39 310 1.1E-171
2 g13095.t8 PANTHER PTHR11879 ASPARTATE AMINOTRANSFERASE 1 392 2.2E-191
3 g13095.t8 PANTHER PTHR11879:SF39 ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL 1 392 2.2E-191
7 g13095.t8 PRINTS PR00799 Aspartate aminotransferase signature 169 188 1.3E-36
4 g13095.t8 PRINTS PR00799 Aspartate aminotransferase signature 200 212 1.3E-36
5 g13095.t8 PRINTS PR00799 Aspartate aminotransferase signature 268 293 1.3E-36
6 g13095.t8 PRINTS PR00799 Aspartate aminotransferase signature 336 354 1.3E-36
1 g13095.t8 Pfam PF00155 Aminotransferase class I and II 21 386 1.3E-87
9 g13095.t8 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 238 251 -
8 g13095.t8 SUPERFAMILY SSF53383 PLP-dependent transferases 2 391 1.31E-110

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009058 biosynthetic process BP
GO:0006520 cellular amino acid metabolic process BP
GO:0008483 transaminase activity MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values