General information for g13107.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 9e2.
Parent gene
- The parent gene g13107 is located on chr_1: 27992122..27993083 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13107 | g13107.t1 | TTS | g13107.t1 | 27990737 | 27990737 |
| chr_1 | g13107 | g13107.t1 | isoform | g13107.t1 | 27990978 | 27992860 |
| chr_1 | g13107 | g13107.t1 | exon | g13107.t1.exon1 | 27990978 | 27991985 |
| chr_1 | g13107 | g13107.t1 | cds | g13107.t1.CDS1 | 27990978 | 27991985 |
| chr_1 | g13107 | g13107.t1 | exon | g13107.t1.exon2 | 27992042 | 27992208 |
| chr_1 | g13107 | g13107.t1 | cds | g13107.t1.CDS2 | 27992042 | 27992208 |
| chr_1 | g13107 | g13107.t1 | exon | g13107.t1.exon3 | 27992322 | 27992354 |
| chr_1 | g13107 | g13107.t1 | cds | g13107.t1.CDS3 | 27992322 | 27992354 |
| chr_1 | g13107 | g13107.t1 | exon | g13107.t1.exon4 | 27992413 | 27992591 |
| chr_1 | g13107 | g13107.t1 | cds | g13107.t1.CDS4 | 27992413 | 27992591 |
| chr_1 | g13107 | g13107.t1 | exon | g13107.t1.exon5 | 27992658 | 27992860 |
| chr_1 | g13107 | g13107.t1 | cds | g13107.t1.CDS5 | 27992658 | 27992860 |
| chr_1 | g13107 | g13107.t1 | TSS | g13107.t1 | 27993083 | 27993083 |
Sequences
>g13107.t1 Gene=g13107 Length=1590
ATGATTATTTGGATTTTATTATTGATTGCCGCAGTCATTTTGCTGTACAAATATGGAACG
AGAAATTTCGATTACTTTCAAAAGAAAGGACTGGCTTTTAATAAGCCTCATTTTCTTGTT
GGGTCACGCCTAAGTACAGTTCTTGGTACAAAAAATATGATCGAAATGCTCACTGAAATT
TATAATGAGCATAGAGATGAAAAAATTTCCGGCATGTTTGAATTCAATCGTCCAGCATAT
TTTATTCGTGACCCAGAGATGATTAAACGACTTTGTATTAAAGAATTTGATTCATTCAGC
GATCATCGACTTATTCTTTCTAAAGAAGCAGAACCTCTCTTTGCTTCTGCACTTTTCGGT
TTGACGGGTCAAAAATGGAGAGACATGCGAGCAACACTCTCTCCAGCGTTTACTGGCAGC
AAAATGCGTCTAATGTTTAAGCTCATAAACGACGTTGGCTCTCAAATGTCGAATACTGTT
CTTGAACAAATAAATAAAGGAGCTGACAACAAAATTGAGTTTAAAGAATTTGCTCAGAAA
TTTACAATCGATATTATAGCAAGTTGCGCATTTGGATTAGAGATAAATTCATTCAATAAT
CCCAATAATGACTTCCTGAGAATTGCAAGAAAAGCAACAAATTTCGCTACCTTTAAGACC
ACAATAAAATTAGTGGGTTTACTTGGTGCACCATGGTTAATGAAAATATTTAAAATCAAG
TTTTTGGATGAAGAATTTTATAAATTCTTTGGTGCAATGATGACAGATACTATAAAAACT
AGAGAAGAGAAGAAAATAACTCGTAATGATATGATCGATTTGATATTGCAAGCAAAACAC
GGTAAACAACTTGATTATGACAATGAAGAGCATACAGTTGATGGTTTCGCAACAGTTGAG
GAATCACAATTAGGAAAAGAAAAAGTTAAGAGAACATGGGAAGATGATGAACTTTTAGCA
CAATGTGTTGGCTTCTTTTTTGGTGGATTTGAAACAGTTTCGAGTGTCATGACTTTTATG
GCTGCTGAATTGATTATTGATCCTAATATTCAGAAAAAATTACAAGACGAAATTGATGAA
GTTCACAAGTCATTGAACGGAGAAACTTTGACATACGAGCATGTACAAAAAATGAAATAC
ATGGATATGGTTGTTTGCGAGACTCTACGAAAATGGCCACCTGCACCAATTGTTGATAGA
AAGTGCACTAAAGAATTTAATTTCGAATATGATGACAAAAAATTCATTATGGAATATGAT
AAAAATTTCTATGTTCCTATCTATTCATTACATCATGATGAACGTTATTTCCCAGAACCA
GAAAAATTCGATCCTGAACGATTTAATGATGAAAATAAGAAAAATATCAGACAAGATTGT
TATATACCTTTTGGTATTGGTCCAAGAAATTGCATTGGAAACCGTTTTGCTTTACTTGAA
GTGAAAACAATTTTTTACTACCTCCTATTAAACTTTACATTTGAAGCGACAAATGAAACT
GAAATTCCCCTCAAATTGGGAAGAAGTCAAACAACATTACAACTTGAAAATGGATTGAAA
TGTGCCTTGATTCCACGAGCTGAAGAATAA
>g13107.t1 Gene=g13107 Length=529
MIIWILLLIAAVILLYKYGTRNFDYFQKKGLAFNKPHFLVGSRLSTVLGTKNMIEMLTEI
YNEHRDEKISGMFEFNRPAYFIRDPEMIKRLCIKEFDSFSDHRLILSKEAEPLFASALFG
LTGQKWRDMRATLSPAFTGSKMRLMFKLINDVGSQMSNTVLEQINKGADNKIEFKEFAQK
FTIDIIASCAFGLEINSFNNPNNDFLRIARKATNFATFKTTIKLVGLLGAPWLMKIFKIK
FLDEEFYKFFGAMMTDTIKTREEKKITRNDMIDLILQAKHGKQLDYDNEEHTVDGFATVE
ESQLGKEKVKRTWEDDELLAQCVGFFFGGFETVSSVMTFMAAELIIDPNIQKKLQDEIDE
VHKSLNGETLTYEHVQKMKYMDMVVCETLRKWPPAPIVDRKCTKEFNFEYDDKKFIMEYD
KNFYVPIYSLHHDERYFPEPEKFDPERFNDENKKNIRQDCYIPFGIGPRNCIGNRFALLE
VKTIFYYLLLNFTFEATNETEIPLKLGRSQTTLQLENGLKCALIPRAEE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g13107.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 14 | 529 | 8.2E-125 |
| 2 | g13107.t1 | PANTHER | PTHR24292 | CYTOCHROME P450 | 4 | 509 | 2.8E-179 |
| 3 | g13107.t1 | PANTHER | PTHR24292:SF90 | CYTOCHROME P450 317A1-RELATED | 4 | 509 | 2.8E-179 |
| 8 | g13107.t1 | PRINTS | PR00463 | E-class P450 group I signature | 317 | 334 | 5.6E-22 |
| 11 | g13107.t1 | PRINTS | PR00385 | P450 superfamily signature | 328 | 345 | 3.2E-9 |
| 7 | g13107.t1 | PRINTS | PR00463 | E-class P450 group I signature | 337 | 363 | 5.6E-22 |
| 9 | g13107.t1 | PRINTS | PR00385 | P450 superfamily signature | 383 | 394 | 3.2E-9 |
| 6 | g13107.t1 | PRINTS | PR00463 | E-class P450 group I signature | 426 | 450 | 5.6E-22 |
| 4 | g13107.t1 | PRINTS | PR00463 | E-class P450 group I signature | 461 | 471 | 5.6E-22 |
| 12 | g13107.t1 | PRINTS | PR00385 | P450 superfamily signature | 462 | 471 | 3.2E-9 |
| 5 | g13107.t1 | PRINTS | PR00463 | E-class P450 group I signature | 471 | 494 | 5.6E-22 |
| 10 | g13107.t1 | PRINTS | PR00385 | P450 superfamily signature | 471 | 482 | 3.2E-9 |
| 1 | g13107.t1 | Pfam | PF00067 | Cytochrome P450 | 35 | 512 | 8.0E-80 |
| 16 | g13107.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 17 | g13107.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 18 | g13107.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 15 | - |
| 19 | g13107.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 19 | - |
| 15 | g13107.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 529 | - |
| 21 | g13107.t1 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 464 | 473 | - |
| 13 | g13107.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 35 | 526 | 3.8E-105 |
| 20 | g13107.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 2 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K17692 (cytochrome P450 family 3 subfamily A43)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
