Gene loci information

Transcript annotation

  • This transcript has been annotated as Cytochrome P450 9e2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13107 g13107.t19 TTS g13107.t19 27990737 27990737
chr_1 g13107 g13107.t19 isoform g13107.t19 27990978 27993083
chr_1 g13107 g13107.t19 exon g13107.t19.exon1 27990978 27991985
chr_1 g13107 g13107.t19 cds g13107.t19.CDS1 27990978 27991985
chr_1 g13107 g13107.t19 exon g13107.t19.exon2 27992042 27992208
chr_1 g13107 g13107.t19 cds g13107.t19.CDS2 27992042 27992208
chr_1 g13107 g13107.t19 exon g13107.t19.exon3 27992322 27992354
chr_1 g13107 g13107.t19 cds g13107.t19.CDS3 27992322 27992354
chr_1 g13107 g13107.t19 exon g13107.t19.exon4 27992413 27992591
chr_1 g13107 g13107.t19 cds g13107.t19.CDS4 27992413 27992591
chr_1 g13107 g13107.t19 exon g13107.t19.exon5 27992658 27992895
chr_1 g13107 g13107.t19 cds g13107.t19.CDS5 27992658 27992860
chr_1 g13107 g13107.t19 exon g13107.t19.exon6 27993023 27993083
chr_1 g13107 g13107.t19 TSS g13107.t19 27993083 27993083

Sequences

>g13107.t19 Gene=g13107 Length=1686
AGATCGAGTGAAGTCGCGAAGGCGAGTGGTTGATAATTTACTTTGCTGAAGTTAATATCA
AATATTTCAAGGTCATTCTAATTCCAGTTTGTCATAATGATTATTTGGATTTTATTATTG
ATTGCCGCAGTCATTTTGCTGTACAAATATGGAACGAGAAATTTCGATTACTTTCAAAAG
AAAGGACTGGCTTTTAATAAGCCTCATTTTCTTGTTGGGTCACGCCTAAGTACAGTTCTT
GGTACAAAAAATATGATCGAAATGCTCACTGAAATTTATAATGAGCATAGAGATGAAAAA
ATTTCCGGCATGTTTGAATTCAATCGTCCAGCATATTTTATTCGTGACCCAGAGATGATT
AAACGACTTTGTATTAAAGAATTTGATTCATTCAGCGATCATCGACTTATTCTTTCTAAA
GAAGCAGAACCTCTCTTTGCTTCTGCACTTTTCGGTTTGACGGGTCAAAAATGGAGAGAC
ATGCGAGCAACACTCTCTCCAGCGTTTACTGGCAGCAAAATGCGTCTAATGTTTAAGCTC
ATAAACGACGTTGGCTCTCAAATGTCGAATACTGTTCTTGAACAAATAAATAAAGGAGCT
GACAACAAAATTGAGTTTAAAGAATTTGCTCAGAAATTTACAATCGATATTATAGCAAGT
TGCGCATTTGGATTAGAGATAAATTCATTCAATAATCCCAATAATGACTTCCTGAGAATT
GCAAGAAAAGCAACAAATTTCGCTACCTTTAAGACCACAATAAAATTAGTGGGTTTACTT
GGTGCACCATGGTTAATGAAAATATTTAAAATCAAGTTTTTGGATGAAGAATTTTATAAA
TTCTTTGGTGCAATGATGACAGATACTATAAAAACTAGAGAAGAGAAGAAAATAACTCGT
AATGATATGATCGATTTGATATTGCAAGCAAAACACGGTAAACAACTTGATTATGACAAT
GAAGAGCATACAGTTGATGGTTTCGCAACAGTTGAGGAATCACAATTAGGAAAAGAAAAA
GTTAAGAGAACATGGGAAGATGATGAACTTTTAGCACAATGTGTTGGCTTCTTTTTTGGT
GGATTTGAAACAGTTTCGAGTGTCATGACTTTTATGGCTGCTGAATTGATTATTGATCCT
AATATTCAGAAAAAATTACAAGACGAAATTGATGAAGTTCACAAGTCATTGAACGGAGAA
ACTTTGACATACGAGCATGTACAAAAAATGAAATACATGGATATGGTTGTTTGCGAGACT
CTACGAAAATGGCCACCTGCACCAATTGTTGATAGAAAGTGCACTAAAGAATTTAATTTC
GAATATGATGACAAAAAATTCATTATGGAATATGATAAAAATTTCTATGTTCCTATCTAT
TCATTACATCATGATGAACGTTATTTCCCAGAACCAGAAAAATTCGATCCTGAACGATTT
AATGATGAAAATAAGAAAAATATCAGACAAGATTGTTATATACCTTTTGGTATTGGTCCA
AGAAATTGCATTGGAAACCGTTTTGCTTTACTTGAAGTGAAAACAATTTTTTACTACCTC
CTATTAAACTTTACATTTGAAGCGACAAATGAAACTGAAATTCCCCTCAAATTGGGAAGA
AGTCAAACAACATTACAACTTGAAAATGGATTGAAATGTGCCTTGATTCCACGAGCTGAA
GAATAA

>g13107.t19 Gene=g13107 Length=529
MIIWILLLIAAVILLYKYGTRNFDYFQKKGLAFNKPHFLVGSRLSTVLGTKNMIEMLTEI
YNEHRDEKISGMFEFNRPAYFIRDPEMIKRLCIKEFDSFSDHRLILSKEAEPLFASALFG
LTGQKWRDMRATLSPAFTGSKMRLMFKLINDVGSQMSNTVLEQINKGADNKIEFKEFAQK
FTIDIIASCAFGLEINSFNNPNNDFLRIARKATNFATFKTTIKLVGLLGAPWLMKIFKIK
FLDEEFYKFFGAMMTDTIKTREEKKITRNDMIDLILQAKHGKQLDYDNEEHTVDGFATVE
ESQLGKEKVKRTWEDDELLAQCVGFFFGGFETVSSVMTFMAAELIIDPNIQKKLQDEIDE
VHKSLNGETLTYEHVQKMKYMDMVVCETLRKWPPAPIVDRKCTKEFNFEYDDKKFIMEYD
KNFYVPIYSLHHDERYFPEPEKFDPERFNDENKKNIRQDCYIPFGIGPRNCIGNRFALLE
VKTIFYYLLLNFTFEATNETEIPLKLGRSQTTLQLENGLKCALIPRAEE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
14 g13107.t19 Gene3D G3DSA:1.10.630.10 Cytochrome p450 14 529 8.2E-125
2 g13107.t19 PANTHER PTHR24292 CYTOCHROME P450 4 509 2.8E-179
3 g13107.t19 PANTHER PTHR24292:SF90 CYTOCHROME P450 317A1-RELATED 4 509 2.8E-179
8 g13107.t19 PRINTS PR00463 E-class P450 group I signature 317 334 5.6E-22
11 g13107.t19 PRINTS PR00385 P450 superfamily signature 328 345 3.2E-9
7 g13107.t19 PRINTS PR00463 E-class P450 group I signature 337 363 5.6E-22
9 g13107.t19 PRINTS PR00385 P450 superfamily signature 383 394 3.2E-9
6 g13107.t19 PRINTS PR00463 E-class P450 group I signature 426 450 5.6E-22
4 g13107.t19 PRINTS PR00463 E-class P450 group I signature 461 471 5.6E-22
12 g13107.t19 PRINTS PR00385 P450 superfamily signature 462 471 3.2E-9
5 g13107.t19 PRINTS PR00463 E-class P450 group I signature 471 494 5.6E-22
10 g13107.t19 PRINTS PR00385 P450 superfamily signature 471 482 3.2E-9
1 g13107.t19 Pfam PF00067 Cytochrome P450 35 512 8.0E-80
16 g13107.t19 Phobius SIGNAL_PEPTIDE Signal peptide region 1 19 -
17 g13107.t19 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 3 -
18 g13107.t19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 4 15 -
19 g13107.t19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 16 19 -
15 g13107.t19 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 20 529 -
21 g13107.t19 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 464 473 -
13 g13107.t19 SUPERFAMILY SSF48264 Cytochrome P450 35 526 3.8E-105
20 g13107.t19 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 2 19 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0020037 heme binding MF
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen MF
GO:0005506 iron ion binding MF
GO:0055114 NA NA

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values