Gene loci information

Transcript annotation

  • This transcript has been annotated as Protein kibra.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13111 g13111.t1 TSS g13111.t1 28006393 28006393
chr_1 g13111 g13111.t1 isoform g13111.t1 28006677 28019232
chr_1 g13111 g13111.t1 exon g13111.t1.exon1 28006677 28006798
chr_1 g13111 g13111.t1 cds g13111.t1.CDS1 28006677 28006798
chr_1 g13111 g13111.t1 exon g13111.t1.exon2 28015620 28016836
chr_1 g13111 g13111.t1 cds g13111.t1.CDS2 28015620 28016836
chr_1 g13111 g13111.t1 exon g13111.t1.exon3 28016902 28017662
chr_1 g13111 g13111.t1 cds g13111.t1.CDS3 28016902 28017662
chr_1 g13111 g13111.t1 exon g13111.t1.exon4 28017741 28017930
chr_1 g13111 g13111.t1 cds g13111.t1.CDS4 28017741 28017930
chr_1 g13111 g13111.t1 exon g13111.t1.exon5 28017994 28018131
chr_1 g13111 g13111.t1 cds g13111.t1.CDS5 28017994 28018131
chr_1 g13111 g13111.t1 exon g13111.t1.exon6 28018201 28018629
chr_1 g13111 g13111.t1 cds g13111.t1.CDS6 28018201 28018629
chr_1 g13111 g13111.t1 exon g13111.t1.exon7 28018693 28019023
chr_1 g13111 g13111.t1 cds g13111.t1.CDS7 28018693 28019023
chr_1 g13111 g13111.t1 exon g13111.t1.exon8 28019082 28019232
chr_1 g13111 g13111.t1 cds g13111.t1.CDS8 28019082 28019232
chr_1 g13111 g13111.t1 TTS g13111.t1 28020060 28020060

Sequences

>g13111.t1 Gene=g13111 Length=3339
ATGAATAGAAATGAAGAGTTGCCTTTGCCTTGTAATTGGGAAAAAGCCCAAGATTATGAT
GGAAAAACATATTACATTGATCATGCGAAAAAGATAACGACATGGATAGATCCAAGAGAT
AGATATACAAAGCCAGAAACTTTTGCAGATTGTATTGGCAATGAGCTTCCATTAGGTTGG
GAAGAAGCATATGATCCACAAATTGGCATCTTTTATATCAATCACAATAGTCAATGTACA
CAGTTAGAAGATCCACGATTAGAATGGAAGGAAATGCAAGAACAAATGTTACGCGAATAC
ATGTCATCAGCAGAAGAGCAGCTAGAGGCAAAGAAAGAAATTTACGATATAAAACAGCAG
AGATTACTGCTAGCACAAGACGAGTACAATCATTTAAATGCATTGGCCACAAGTCGAACG
AGTTTATGTTCATCAGCGAGTTCATGCAGTACCAAATTTGATCCTGAACTTCTTCGTGCT
GATCTTGCGTTGGCTAAAGAACGTGTTTATCGTTTACGAACAGAAATGGATCGAATTCAG
CATGAAATGTCATATACAAAGAAAGGAGTTGAAACGCTGCATAATGTGGAACAGAAGCTT
AATAATCATCAGAATGGTTGCTATAGTGTAAATGAAGCACAAGCAATAATGGAAGAAGTG
AAGAAAATTCAAAAATCACTTTTATTGGGCGAAAGAGAAAAGAAAGAACTTATGCATAGT
CTAGCACAAGTAAAAGAAGACCTCACGAGACTGCAGCTTAGGCAAGAAAGTCCCGATGCA
AGTACTTTCAATCTCAATGATCGAGTATCAGCTGCTTCACAAACTGACATCTGTCTTGAT
GCATTTCCAATTGGTTCACGTGAAATGGCAAAACTTAGAATCAAATATGATGAATATCGT
AAGAAAGTGAAGGACATTCAAGAGAAACTGGCATCAATGGAGGAAAGAATAAGACCAGGT
GAACTTGAGTCTGATCAGGATCGATTATTGTTATTCCAAGAGAAGAAGCAGTTGTTACTT
GAATATCGTAGCATTTCGCCACGGTCACGATCAGAAGAAGAAATGATCAAAATTAAGGAA
TTGTGCAAGAAACTCGAGTCAGACTTAAATAATGCTTATGAAGAATCAAATCAATGCATC
GCAAATCGACTGAAATTACATGAAGAAAAACAGATGCTACTACAAGAGCTACTCGATGCA
TTGCGTGAAGTAACACATCTTGAAAATCAATTAAAATCTGTCTCAGCCAGCACATTATCA
ATAAGTAGCAGTGGATCGAGTCTTGGTTCATTATCAACAGCAAGCAGTAAAGGATCATTA
AGTGGTATAAGCTTTACTGATATTTACGGTGATCCATTGATGACAGACCCGAGAATTGAC
ATGGTCGATCTCTCGAGACAAATTCAATACTTCCTGCCACCGTCAGCTAGTGACATTTCT
TTGTCATCACGAAGTAGTATATCTGCAGTAAATGAAACACCTCCTGCATCTCCACTTAAG
CCTGAGCCAATGTATGAAAATGCTCAAGAAGCATTGGCTGCTGCATTACTTGAAGCTATG
CCATCAACATCGCAACAACTTGCTGACTATAGTCGTCTCAATCAGCATTTAGCAGATTTT
GCAAAACAGAAGCCATTGTCACCAATTTATGAAAAAGCCTTACTCGATATTCCACAATCG
GCTCTAAGTCGTTCATCATCAGCATCAAATACAGTATCAGCAGCAGTTAGTGATGAATCA
GTAGCTGGTGATAGTGGAGTTTTTGAGGCATCGCGTGCATCAACACAAATGAAAGAATCA
GCACAAATTCAAGTGACACTTAAATATTTAACAGATGAAAGTGCACTGCTGATTACAATC
GAAAGAGCTCGCAATCTTATGGTTCTTGGTCTTCCATCAGGCTGTCAATTGTATATTAAA
GCAATTCTACTTCCAAGCACATCAGGCAGTGCTGTTGTGTTGCGAACAAAAACATTCAAT
GAGTTCGTTAAGCCAATCTTTGGCGCGAGCGTGCAAATTCCAATTGCGCTAAGTAAAGTT
TATACAAAATCTCTACAGATTAAGATAATGATGTTGCTTAGTCAAAAGGAGGATTGGGTG
GGAAGCGCTCAAATAAGCTTAGCAGAATTTAGTACACAGCAAGATGGAAACAGCAGATGG
TATAACATAATTAGTCGTGAAAATATGAACGAGACAGAAGTAGATGAGAATTTAATTGCT
GCAAAGGAAGAGTCGTCTGATGAGTCAACAGTCATTTCGTCACAGACTTCAACTTTAACG
AGAAATCAAGGTCATGATGAAATGCAACAAGCAGTTTTAGCAATGAATCTTCAAGAGCTT
AGCTTATGCAGTGATGATGAAGAAAGTGATGAAGAAGAAGGCAATGATGAGGCATGTGGT
GGAACTTTAGAAGAAGCTTATGATGATGATTCAACAGCTCAAATGTTAGAAACATACATG
AACGAAGTACAAAATTACAGTAATGTAGTGAATGTGGAAACAGTAGATGCTCAAACAAAT
ACTGAACTCTTGCCGGATTATCAGCAGCGCAATTTGATGATGCTTAGACTTAGAGATCGA
ACTTCAGCTTCAACTACATCGCTGCGTGATCCAAAAATTTACCCCATCGAGGATCGCAGT
AGTTTGGTGAATGTAAAAAGGTCACAAACTTTTTCGCCAAGTGCTGCTTGTAACAAATCG
CGATACATTTGTCGACGAAGTGATAGTGATAGTGCAATGCATTTCAATATAACCGCCGCA
GTAGCTGCACAACCTCAAGCAGTTCATTTTAGACGTGGTGCTGTCGAGAGACGATCATTG
AGATATCATGGAAAAGTCACTCGTCTTCTTTCAACAAAAGTTAATCCTGGCGGACTTCCA
CCAAGAACAAGTTTAGACTTAGAACTTGACTTAAAAGCTCAACAAACTCGTCTTGAGTCA
CTCAATGATGAAATTACAAAACTCAGAGAGTTAAAGCAACGTTTGGAACAAGCGCGTGAT
GCCAATGATGTTCAAATTGCAAATTGGGCTTTAGAAAATGAAGAATTCAAGTCATTGGTC
AATGGTTGTGGTTTAAATTCGGAAGAAGATAAACGAGTGCAAAAACTTCTTCGTAAGACA
TCAAAAGAAATTTACAAGCTGCGCAAGGCTAAAGTTGATAGAACGAAGCCAGATATGATT
TCTTTCAAAGAAAAAATGGCATTTTTCACTAGACGTGGAGCATCATCAGTACCTGAAATT
CCATCAAACTCAACAAATCACAACAATGATAGAGAAATTACTGAAGAGGAAGCAAAAAAG
TACAGCTTTTTATTGGATAGAGATGGCGTAGAAGTCTGA

>g13111.t1 Gene=g13111 Length=1112
MNRNEELPLPCNWEKAQDYDGKTYYIDHAKKITTWIDPRDRYTKPETFADCIGNELPLGW
EEAYDPQIGIFYINHNSQCTQLEDPRLEWKEMQEQMLREYMSSAEEQLEAKKEIYDIKQQ
RLLLAQDEYNHLNALATSRTSLCSSASSCSTKFDPELLRADLALAKERVYRLRTEMDRIQ
HEMSYTKKGVETLHNVEQKLNNHQNGCYSVNEAQAIMEEVKKIQKSLLLGEREKKELMHS
LAQVKEDLTRLQLRQESPDASTFNLNDRVSAASQTDICLDAFPIGSREMAKLRIKYDEYR
KKVKDIQEKLASMEERIRPGELESDQDRLLLFQEKKQLLLEYRSISPRSRSEEEMIKIKE
LCKKLESDLNNAYEESNQCIANRLKLHEEKQMLLQELLDALREVTHLENQLKSVSASTLS
ISSSGSSLGSLSTASSKGSLSGISFTDIYGDPLMTDPRIDMVDLSRQIQYFLPPSASDIS
LSSRSSISAVNETPPASPLKPEPMYENAQEALAAALLEAMPSTSQQLADYSRLNQHLADF
AKQKPLSPIYEKALLDIPQSALSRSSSASNTVSAAVSDESVAGDSGVFEASRASTQMKES
AQIQVTLKYLTDESALLITIERARNLMVLGLPSGCQLYIKAILLPSTSGSAVVLRTKTFN
EFVKPIFGASVQIPIALSKVYTKSLQIKIMMLLSQKEDWVGSAQISLAEFSTQQDGNSRW
YNIISRENMNETEVDENLIAAKEESSDESTVISSQTSTLTRNQGHDEMQQAVLAMNLQEL
SLCSDDEESDEEEGNDEACGGTLEEAYDDDSTAQMLETYMNEVQNYSNVVNVETVDAQTN
TELLPDYQQRNLMMLRLRDRTSASTTSLRDPKIYPIEDRSSLVNVKRSQTFSPSAACNKS
RYICRRSDSDSAMHFNITAAVAAQPQAVHFRRGAVERRSLRYHGKVTRLLSTKVNPGGLP
PRTSLDLELDLKAQQTRLESLNDEITKLRELKQRLEQARDANDVQIANWALENEEFKSLV
NGCGLNSEEDKRVQKLLRKTSKEIYKLRKAKVDRTKPDMISFKEKMAFFTRRGASSVPEI
PSNSTNHNNDREITEEEAKKYSFLLDRDGVEV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
18 g13111.t1 CDD cd00201 WW 10 40 8.82153E-9
19 g13111.t1 CDD cd00201 WW 57 87 5.45312E-6
16 g13111.t1 Coils Coil Coil 101 121 -
12 g13111.t1 Coils Coil Coil 162 182 -
17 g13111.t1 Coils Coil Coil 234 254 -
15 g13111.t1 Coils Coil Coil 289 316 -
14 g13111.t1 Coils Coil Coil 348 410 -
13 g13111.t1 Coils Coil Coil 964 1008 -
11 g13111.t1 Gene3D G3DSA:2.20.70.10 - 1 41 4.4E-14
10 g13111.t1 Gene3D G3DSA:2.20.70.10 - 56 88 3.3E-12
9 g13111.t1 Gene3D G3DSA:2.60.40.150 - 599 725 3.5E-17
25 g13111.t1 MobiDBLite mobidb-lite consensus disorder prediction 743 763 -
23 g13111.t1 MobiDBLite mobidb-lite consensus disorder prediction 744 763 -
24 g13111.t1 MobiDBLite mobidb-lite consensus disorder prediction 1073 1095 -
3 g13111.t1 PANTHER PTHR14791:SF22 PROTEIN KIBRA 5 454 8.5E-199
5 g13111.t1 PANTHER PTHR14791 BOMB/KIRA PROTEINS 5 454 8.5E-199
2 g13111.t1 PANTHER PTHR14791:SF22 PROTEIN KIBRA 478 1082 8.5E-199
4 g13111.t1 PANTHER PTHR14791 BOMB/KIRA PROTEINS 478 1082 8.5E-199
1 g13111.t1 Pfam PF00397 WW domain 9 38 5.5E-7
22 g13111.t1 ProSitePatterns PS01159 WW/rsp5/WWP domain signature. 13 38 -
26 g13111.t1 ProSiteProfiles PS50020 WW/rsp5/WWP domain profile. 7 40 14.856
27 g13111.t1 ProSiteProfiles PS50020 WW/rsp5/WWP domain profile. 54 87 12.649
20 g13111.t1 SMART SM00456 ww_5 8 40 1.0E-9
21 g13111.t1 SMART SM00456 ww_5 55 87 6.9E-5
7 g13111.t1 SUPERFAMILY SSF51045 WW domain 4 39 2.82E-11
8 g13111.t1 SUPERFAMILY SSF51045 WW domain 54 87 1.1E-8
6 g13111.t1 SUPERFAMILY SSF49562 C2 domain (Calcium/lipid-binding domain, CaLB) 602 729 2.5E-13

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values