General information for g13248.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Multiple inositol polyphosphate phosphatase 1.
Parent gene
- The parent gene g13248 is located on chr_1: 28770185..28771592 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13248 | g13248.t1 | isoform | g13248.t1 | 28770185 | 28771592 |
| chr_1 | g13248 | g13248.t1 | exon | g13248.t1.exon1 | 28770185 | 28771261 |
| chr_1 | g13248 | g13248.t1 | cds | g13248.t1.CDS1 | 28770185 | 28771261 |
| chr_1 | g13248 | g13248.t1 | exon | g13248.t1.exon2 | 28771320 | 28771592 |
| chr_1 | g13248 | g13248.t1 | cds | g13248.t1.CDS2 | 28771320 | 28771592 |
| chr_1 | g13248 | g13248.t1 | TSS | g13248.t1 | NA | NA |
| chr_1 | g13248 | g13248.t1 | TTS | g13248.t1 | NA | NA |
Sequences
>g13248.t1 Gene=g13248 Length=1350
ATGAAATTTCTAGCAGTAGCAATTATTTTTGTCACAGTAGCTTCTGCAATTTCTCAAACA
GCTCCTGACCCAACGTATTGTTATGCATCAGATCCAATAAGATCACAACAACCACGTTGG
GCTGACAGAACTTCAAATGAATTCATTCGTGGTCATTCAGTGAATCCTCAAGTCTCATCA
TGCACACCAGCAAGATTCTGGCTTTACATGCGTCATGGTGACAGACTACCAAGCACTAAT
GACATTAATCGAATGGTTCCATTTACCAATACACAACATCCAAATATCATTAATGCATAT
AATGCTGGTCACAGTTCGCTTTGTCCACCAGATTTTACAGCAATCAATACATGGAGATGG
GATTCAAATATTACAGTTGCAATTGAACAATTTTTGACTGTATCGGGATGGAATATTGTT
AAAGAACTCGCAAGACGTTATCAAAGAGCTTTCCCAACTCTTCTACCACCAATCTATGAT
AGAACTCGTTTTTCATTCCGCCACACTGATCGTCAACGTACACAAGCAACTGTTCGTGCC
TTTGCTGATGGTCTTTTTGGTGAAAATGCATATCGCAATGTTATCATTCAAGACCCACCA
AATCCAGATCCTCTTTTGAGACCACACGATAATTGCCCAGCTTATGATGTTGCAAGTAAC
ACTCAAGCTGAACGTGATAGATGGCAAAATTCACAAGAATTCCAAGCCACATTGACAAGA
ATCAACGACAAATTAGGACTGACTGGAAATCAACGATTGTCAGCTCGTCAAGCACGTACA
ATGTGGGAAATTTGTCAATTCCATCAACTTTGGGATACAACTCAAGATGCTCCATTCTGT
GGTGCTATTTCACCATTTGATAACTTGCGATTGGAATATTTTGAAGATATTGATGAGTAT
TACACTTCTGGTTATGGTTTAAACCCTGTAAGACTTGCTGAGAATTTGAATTGTCCGCTC
ATGCAAGATTTAATTTCATTTTTGACATCAAATGATCCAAATGAAGAAACTGTAAGAATT
AGAAGTGCACATCAAACTTCATTCCAATTATTCTTGGTTTCACTTGGTGTTTTCCGTGAT
GAAAAACCATTATTGGCTACAAATTTCGCTCAACAAAGCAATAGATTGTGGAGAACTTCT
TACATTTCTCCAATGGCAACAAATATTGTCGCTGTTCGATACAATTGTGCTGGTGTTGAC
AACGATGATGTTCTTTTCCTCATGAATGAGAAACCACTAGTCATTCCTGGTTGTGCCTCA
ACAGGTCTCTGCAAAGTTCGTGATATTGTTGCTCGCTATAGTCGATTTATTAGTGCCAAT
TGTGCTACTCTTTCTTGCAGTACGCTTTAA
>g13248.t1 Gene=g13248 Length=449
MKFLAVAIIFVTVASAISQTAPDPTYCYASDPIRSQQPRWADRTSNEFIRGHSVNPQVSS
CTPARFWLYMRHGDRLPSTNDINRMVPFTNTQHPNIINAYNAGHSSLCPPDFTAINTWRW
DSNITVAIEQFLTVSGWNIVKELARRYQRAFPTLLPPIYDRTRFSFRHTDRQRTQATVRA
FADGLFGENAYRNVIIQDPPNPDPLLRPHDNCPAYDVASNTQAERDRWQNSQEFQATLTR
INDKLGLTGNQRLSARQARTMWEICQFHQLWDTTQDAPFCGAISPFDNLRLEYFEDIDEY
YTSGYGLNPVRLAENLNCPLMQDLISFLTSNDPNEETVRIRSAHQTSFQLFLVSLGVFRD
EKPLLATNFAQQSNRLWRTSYISPMATNIVAVRYNCAGVDNDDVLFLMNEKPLVIPGCAS
TGLCKVRDIVARYSRFISANCATLSCSTL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g13248.t1 | CDD | cd07061 | HP_HAP_like | 141 | 409 | 3.53448E-19 |
| 7 | g13248.t1 | Gene3D | G3DSA:3.40.50.1240 | - | 68 | 443 | 3.9E-76 |
| 2 | g13248.t1 | PANTHER | PTHR20963:SF48 | MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 | 15 | 448 | 5.1E-97 |
| 3 | g13248.t1 | PANTHER | PTHR20963 | MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED | 15 | 448 | 5.1E-97 |
| 13 | g13248.t1 | PIRSF | PIRSF000894 | Acid_Ptase | 1 | 448 | 5.8E-62 |
| 1 | g13248.t1 | Pfam | PF00328 | Histidine phosphatase superfamily (branch 2) | 70 | 400 | 5.5E-17 |
| 9 | g13248.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 20 | - |
| 10 | g13248.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 11 | g13248.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 14 | - |
| 12 | g13248.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 20 | - |
| 8 | g13248.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 21 | 449 | - |
| 4 | g13248.t1 | SUPERFAMILY | SSF53254 | Phosphoglycerate mutase-like | 45 | 444 | 5.05E-55 |
| 6 | g13248.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 16 | - |
| 15 | g13248.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
| 5 | g13248.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 16 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03103 (multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
