Gene loci information

Transcript annotation

  • This transcript has been annotated as Pre-mRNA-splicing factor RBM22.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13359 g13359.t4 TSS g13359.t4 29509895 29509895
chr_1 g13359 g13359.t4 isoform g13359.t4 29509989 29511391
chr_1 g13359 g13359.t4 exon g13359.t4.exon1 29509989 29509991
chr_1 g13359 g13359.t4 exon g13359.t4.exon2 29510057 29510194
chr_1 g13359 g13359.t4 cds g13359.t4.CDS1 29510087 29510194
chr_1 g13359 g13359.t4 exon g13359.t4.exon3 29510522 29511391
chr_1 g13359 g13359.t4 cds g13359.t4.CDS2 29510522 29511391
chr_1 g13359 g13359.t4 TTS g13359.t4 29511462 29511462

Sequences

>g13359.t4 Gene=g13359 Length=1011
GAGAAAAGTCAATAAAACTTATTTTGCTTCAAAATGGCTATGAGCAAAACAACATCTACT
TATAATCGAACGAATTGGGAAGATTCAGAGTTTCCTATATTGTGTCAAACATGTCTAGGA
GATAATCCTTATCTTCGAATGATTCAAGATGAAATCCCACAAAGTGATGTAAATAAAGAA
TATTATTTGCAAAATGTTGAAAAGCAAATGGCAATGAATGATGGACAAATGCCTGGTGGT
GGAAAAGCTCAACAAGCTTCAGATGTTTTATCTAAATTAGCTCGCACTACACCATATTAC
AAACGAAATCTTCCTCACATTTGCTCATTTTGGGTAAAAGGAGAATGTAAAAGAGGTGAA
GAGTGTCCATATAGACATGAAAAACCAAACGATGTAGACGATCCTCTCTCAGAACAAAAT
ATTCGTGATCGATATTATGGTGTTAACGATCCAGTAGCTGAAAAGTTACTTAAAAGAGCT
GCTTCATTACCTGTCCTTGAAACTCCTAGTGACAAGACAATAACTACATTATATTGTGGT
AATGTCGGTGAACATTTGACCGAAGTTGATATAAGAGATCAATTTTATCAATATGGAGAA
ATTAGAAATGTAACACTTGTGCCGAAACAACAGTGTGCTTTCGTACAGTTTACCAAACGT
TCTTCAGCTGAATTGGCAGCAGAGAAGACCTTCAATAAATTGGTTCTTGGTGGTAAAAAA
TTGAGCATACGATGGGCATACTCACAAGCAAAACAAGCCACAGCCACATCATCATCATCA
CAATTGCGGCCTCGTATTGATCCCCGTTTAGATCCTGTACCTGGACTCCCCGATTTACCA
ACACCAAACGATTATTTCAATTTGAATGCAAATGATATGATGGTTCTACCAGCGGGCGTT
AAACTTGCACAAATTCCACAACAATTTTTGCCACCCTCATTACCAAATACATCATCTGGA
ATACATTATCCTTCTATGGATCCAAGTCGATTAGGCGCACTACAAAAATAA

>g13359.t4 Gene=g13359 Length=325
MAMSKTTSTYNRTNWEDSEFPILCQTCLGDNPYLRMIQDEIPQSDVNKEYYLQNVEKQMA
MNDGQMPGGGKAQQASDVLSKLARTTPYYKRNLPHICSFWVKGECKRGEECPYRHEKPND
VDDPLSEQNIRDRYYGVNDPVAEKLLKRAASLPVLETPSDKTITTLYCGNVGEHLTEVDI
RDQFYQYGEIRNVTLVPKQQCAFVQFTKRSSAELAAEKTFNKLVLGGKKLSIRWAYSQAK
QATATSSSSQLRPRIDPRLDPVPGLPDLPTPNDYFNLNANDMMVLPAGVKLAQIPQQFLP
PSLPNTSSGIHYPSMDPSRLGALQK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g13359.t4 CDD cd12224 RRM_RBM22 163 235 3.55221E-41
8 g13359.t4 Gene3D G3DSA:4.10.1000.10 CCCH zinc finger 83 132 5.2E-7
9 g13359.t4 Gene3D G3DSA:3.30.70.330 - 156 254 7.8E-18
13 g13359.t4 MobiDBLite mobidb-lite consensus disorder prediction 306 325 -
3 g13359.t4 PANTHER PTHR14089 PRE-MRNA-SPLICING FACTOR RBM22 3 40 3.2E-104
5 g13359.t4 PANTHER PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 3 40 3.2E-104
2 g13359.t4 PANTHER PTHR14089 PRE-MRNA-SPLICING FACTOR RBM22 39 322 3.2E-104
4 g13359.t4 PANTHER PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 39 322 3.2E-104
1 g13359.t4 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 166 230 4.3E-10
14 g13359.t4 ProSiteProfiles PS50103 Zinc finger C3H1-type profile. 96 118 14.774
15 g13359.t4 ProSiteProfiles PS50102 Eukaryotic RNA Recognition Motif (RRM) profile. 164 237 13.72
11 g13359.t4 SMART SM00356 c3hfinal6 91 117 3.0E-5
12 g13359.t4 SMART SM00360 rrm1_1 165 233 3.3E-14
7 g13359.t4 SUPERFAMILY SSF90229 CCCH zinc finger 95 116 2.49E-6
6 g13359.t4 SUPERFAMILY SSF54928 RNA-binding domain, RBD 158 241 2.17E-18

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0046872 metal ion binding MF
GO:0003723 RNA binding MF
GO:0003676 nucleic acid binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed