General information for g13361.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit alpha type-1.
Parent gene
- The parent gene g13361 is located on chr_1: 29514666..29516041 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13361 | g13361.t1 | TTS | g13361.t1 | 29514363 | 29514363 |
| chr_1 | g13361 | g13361.t1 | isoform | g13361.t1 | 29514666 | 29515748 |
| chr_1 | g13361 | g13361.t1 | exon | g13361.t1.exon1 | 29514666 | 29515088 |
| chr_1 | g13361 | g13361.t1 | cds | g13361.t1.CDS1 | 29514666 | 29515088 |
| chr_1 | g13361 | g13361.t1 | exon | g13361.t1.exon2 | 29515175 | 29515271 |
| chr_1 | g13361 | g13361.t1 | cds | g13361.t1.CDS2 | 29515175 | 29515271 |
| chr_1 | g13361 | g13361.t1 | exon | g13361.t1.exon3 | 29515328 | 29515578 |
| chr_1 | g13361 | g13361.t1 | cds | g13361.t1.CDS3 | 29515328 | 29515578 |
| chr_1 | g13361 | g13361.t1 | exon | g13361.t1.exon4 | 29515746 | 29515748 |
| chr_1 | g13361 | g13361.t1 | cds | g13361.t1.CDS4 | 29515746 | 29515748 |
| chr_1 | g13361 | g13361.t1 | TSS | g13361.t1 | 29515842 | 29515842 |
Sequences
>g13361.t1 Gene=g13361 Length=774
ATGTTTCGCAATCAATATGATAGTGATGTTACTGTTTGGAGTCCACAAGGACGAATTCAT
CAAGTTGAATATGCAATGGAAGCTGTAAAATTAGGATCAGCTACTGTCGGCTTAAAGTCA
AAAGATTATGCAGTTTTGATTGCATTGAAAAGAGCAACATCTGAATTGTCAGCTCATCAA
CAAAAAATTCTTCGTATTGATGATCATATTGGCATTTCGATGGCTGGAATTACTGCTGAT
GCTCGTGTTCTATGTCGCTATATGCGTCAGGAATGCATAAATCATAAGTATTCTTATGGT
AGAAATCATCCAGTTGGTCGCTTGATTAATTTATTAGGACTTAAGATGCAGACTTGTCCA
AGTGCAAACTTTTACGATTGCAAAGCAATGGCAATTGGTGCACGCTCTCAAAGTGCAAGA
ACTTATCTCGAGAAGCATTTGAATGAATTCAAAGATTGCAATCTTTCTGATTTGATTAAT
CATGGTGTTCGTGCTTTTGCGGGTACATTACCAAACGAAACTAAATTGAACAATAAGAAC
TTGTCAATTTGTGTTGTTGGAAAGAATTATAAATTCCATTGCTTAGACGAAACCGAGTTG
GAAAAATATATTACTGCTGAAATCGTTGGAACTCAACCTACTTCTTCTGCTAGTGATTCT
TCAGAGGTAGGCGTTGGAAGAACCGAAAGACATGGCGAAGAACAGCCGCCAACTTTAAAC
CCACAAGATCCAACTCCAGCAGAACCTGCTACCGAAGATCGAAGAATGCAATAA
>g13361.t1 Gene=g13361 Length=257
MFRNQYDSDVTVWSPQGRIHQVEYAMEAVKLGSATVGLKSKDYAVLIALKRATSELSAHQ
QKILRIDDHIGISMAGITADARVLCRYMRQECINHKYSYGRNHPVGRLINLLGLKMQTCP
SANFYDCKAMAIGARSQSARTYLEKHLNEFKDCNLSDLINHGVRAFAGTLPNETKLNNKN
LSICVVGKNYKFHCLDETELEKYITAEIVGTQPTSSASDSSEVGVGRTERHGEEQPPTLN
PQDPTPAEPATEDRRMQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g13361.t1 | Coils | Coil | Coil | 256 | 257 | - |
| 8 | g13361.t1 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 2 | 117 | 3.5E-45 |
| 9 | g13361.t1 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 118 | 208 | 5.0E-22 |
| 13 | g13361.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 211 | 257 | - |
| 4 | g13361.t1 | PANTHER | PTHR11599:SF12 | PROTEASOME SUBUNIT ALPHA TYPE-1 | 1 | 119 | 1.6E-81 |
| 6 | g13361.t1 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 1 | 119 | 1.6E-81 |
| 3 | g13361.t1 | PANTHER | PTHR11599:SF12 | PROTEASOME SUBUNIT ALPHA TYPE-1 | 117 | 231 | 1.6E-81 |
| 5 | g13361.t1 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 117 | 231 | 1.6E-81 |
| 2 | g13361.t1 | Pfam | PF10584 | Proteasome subunit A N-terminal signature | 6 | 28 | 4.9E-13 |
| 1 | g13361.t1 | Pfam | PF00227 | Proteasome subunit | 29 | 117 | 5.4E-25 |
| 11 | g13361.t1 | ProSitePatterns | PS00388 | Proteasome alpha-type subunits signature. | 6 | 28 | - |
| 14 | g13361.t1 | ProSiteProfiles | PS51475 | Proteasome alpha-type subunit profile. | 21 | 204 | 55.149 |
| 12 | g13361.t1 | SMART | SM00948 | Proteasome_A_N_2 | 6 | 28 | 6.7E-10 |
| 7 | g13361.t1 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 4 | 205 | 3.66E-59 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019773 | proteasome core complex, alpha-subunit complex | CC |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0006511 | ubiquitin-dependent protein catabolic process | BP |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02725 (20S proteasome subunit alpha 6)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
