Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Proteasome subunit alpha type-1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13361 g13361.t16 TTS g13361.t16 29514363 29514363
chr_1 g13361 g13361.t16 isoform g13361.t16 29514666 29516041
chr_1 g13361 g13361.t16 exon g13361.t16.exon1 29514666 29515255
chr_1 g13361 g13361.t16 cds g13361.t16.CDS1 29514666 29515052
chr_1 g13361 g13361.t16 exon g13361.t16.exon2 29515338 29515558
chr_1 g13361 g13361.t16 exon g13361.t16.exon3 29515783 29516041
chr_1 g13361 g13361.t16 TSS g13361.t16 NA NA

Sequences

>g13361.t16 Gene=g13361 Length=1070
TGTATGCAATTAAACAAATTTTAAATGGTATAACCTATGCATTAAAATACTTTTTTAAGT
AGAACAACTTTACTTTCACTAAAATTATAAATTGTTAATGGTTTTTTTTAAGAAATTATC
CATAGACTGACATTAGAAATGACCACTTAACGGTTTTGAAATATTTAAAAAAATTTGAAA
AATTGTGCCCAGCTCAATGAATTGCAATTCAAAAAAATTATTTCTCAAAATAACAAGTCT
GAAATTAAAATTTATTTTCTGATGTTACTGTTTGGAGTCCACAAGGACGAATTCATCAAG
TTGAATATGCAATGGAAGCTGTAAAATTAGGATCAGCTACTGTCGGCTTAAAGTCAAAAG
ATTATGCAGTTTTGATTGCATTGAAAAGAGCAACATCTGAATTGTCAGCTCATCAACAAA
AAATTCTTCGTATTGATGATCATATTGGCATTTCGATGGCTGGAATTACTGCTGATGCTC
GAATGCATAAATCATAAGTATTCTTATGGTAGAAATCATCCAGTTGGTCGCTTGATTAAT
TTATTAGGACTTAAGATGCAGGTGTGCACTCAGCGTTATGACCGTCGTCCTTATGGTGTT
GGTTTGCTTGTTGCTGGTTACGATGATCAAGGACCACATATTATCAGACTTGTCCAAGTG
CAAACTTTTACGATTGCAAAGCAATGGCAATTGGTGCACGCTCTCAAAGTGCAAGAACTT
ATCTCGAGAAGCATTTGAATGAATTCAAAGATTGCAATCTTTCTGATTTGATTAATCATG
GTGTTCGTGCTTTTGCGGGTACATTACCAAACGAAACTAAATTGAACAATAAGAACTTGT
CAATTTGTGTTGTTGGAAAGAATTATAAATTCCATTGCTTAGACGAAACCGAGTTGGAAA
AATATATTACTGCTGAAATCGTTGGAACTCAACCTACTTCTTCTGCTAGTGATTCTTCAG
AGGTAGGCGTTGGAAGAACCGAAAGACATGGCGAAGAACAGCCGCCAACTTTAAACCCAC
AAGATCCAACTCCAGCAGAACCTGCTACCGAAGATCGAAGAATGCAATAA

>g13361.t16 Gene=g13361 Length=128
MAIGARSQSARTYLEKHLNEFKDCNLSDLINHGVRAFAGTLPNETKLNNKNLSICVVGKN
YKFHCLDETELEKYITAEIVGTQPTSSASDSSEVGVGRTERHGEEQPPTLNPQDPTPAEP
ATEDRRMQ

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g13361.t16 Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate 1 79 7.1E-17
5 g13361.t16 MobiDBLite mobidb-lite consensus disorder prediction 79 94 -
6 g13361.t16 MobiDBLite mobidb-lite consensus disorder prediction 79 128 -
2 g13361.t16 PANTHER PTHR11599:SF12 PROTEASOME SUBUNIT ALPHA TYPE-1 1 104 3.8E-14
3 g13361.t16 PANTHER PTHR11599 PROTEASOME SUBUNIT ALPHA/BETA 1 104 3.8E-14
1 g13361.t16 Pfam PF00227 Proteasome subunit 1 57 2.3E-5
4 g13361.t16 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 1 76 1.66E-12

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0019773 proteasome core complex, alpha-subunit complex CC
GO:0051603 proteolysis involved in cellular protein catabolic process BP
GO:0005839 proteasome core complex CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values