General information for g13377.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Epoxide hydrolase 3.
Parent gene
- The parent gene g13377 is located on chr_1: 29604587..29606004 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13377 | g13377.t1 | TTS | g13377.t1 | 29604474 | 29604474 |
| chr_1 | g13377 | g13377.t1 | isoform | g13377.t1 | 29604587 | 29606004 |
| chr_1 | g13377 | g13377.t1 | exon | g13377.t1.exon1 | 29604587 | 29605056 |
| chr_1 | g13377 | g13377.t1 | cds | g13377.t1.CDS1 | 29604587 | 29605056 |
| chr_1 | g13377 | g13377.t1 | exon | g13377.t1.exon2 | 29605119 | 29605223 |
| chr_1 | g13377 | g13377.t1 | cds | g13377.t1.CDS2 | 29605119 | 29605223 |
| chr_1 | g13377 | g13377.t1 | exon | g13377.t1.exon3 | 29605502 | 29605739 |
| chr_1 | g13377 | g13377.t1 | cds | g13377.t1.CDS3 | 29605502 | 29605739 |
| chr_1 | g13377 | g13377.t1 | exon | g13377.t1.exon4 | 29605804 | 29606004 |
| chr_1 | g13377 | g13377.t1 | cds | g13377.t1.CDS4 | 29605804 | 29606004 |
| chr_1 | g13377 | g13377.t1 | TSS | g13377.t1 | 29606084 | 29606084 |
Sequences
>g13377.t1 Gene=g13377 Length=1014
ATGACCACACCAATTGATGTGATAAAATTTTTAGTCTTTAATTTTTTGACAATTTTTTAC
TCGGCTTGTATTGGTATTACTATCGTGATAAATTACATATTTAATTCTAAATCACGTTTT
TGGGAAGTGAAAGATCGTCCAGAGCCACCAGCTGCACTTAAGAGTGAAGAGCATGGTGTT
CATAAGTTTATTCAAGTGAATGGCATCAAACTTCATTATGTGGAGAAAGGCAATCCAACT
AAACCATTGATTGTTTTCGTTCATGGTTTTCCAGAGTTTTGGTATAGTTGGCGGCATCAA
ATTAAAGAATTTAGTAAAGATTATTGGACGATAACAATTGATCAGCGTGGATATGGAGAT
TCAGAAAAGCCAAGTAAAATTTCTGAATATCATATCAATAACATGGCTGATGATATACGT
GCACTAGTAAAGAAGTTGGGTAGAGAAAAATTTATACTTATTGCTCATGACTGGGGTGCT
GCAGTTGGTTTCAACTATGTTTATCGTTATATGGACACAATTGAAAAATATGTTATGATA
GGAGGCCCACCTAGTGAAGCATGGAAAAAATTGATTGTCAGTTCACCAAAACAATTTATT
ATGAGTTGGTACATTTTTTTCTTTCAAATGCCTTGGCTTCCTGAATTTGTCATTCGTTGT
AACGATTTGAAATCGTTTGATACTATGAGATTGGGTTCAAAGGAAGACGTTGAATGCTTC
AAATATACTTTTTCTAAACCAGGTGCATTAACTTCACCAATTAATTATTATCGTGCAATA
AAAGTGTTAAACCCTGACCCTCCATTAAAGAAGCCAGCAAATTGTGCACCAGGACTTTTT
TTGTTGGGCGAATATGATAAATATATAGCACGCTCGACAGGAAAGTTAGCTAAGGCTGAA
CTTGATAATTTAGATTTTAAACTAATTATGAGTGCAAACCATTTTGCACAACAACATAAA
CCAGAAGAAACAAATCGCATGATTCGTGAATTTCTTGATAAGAAAATGCAGTAA
>g13377.t1 Gene=g13377 Length=337
MTTPIDVIKFLVFNFLTIFYSACIGITIVINYIFNSKSRFWEVKDRPEPPAALKSEEHGV
HKFIQVNGIKLHYVEKGNPTKPLIVFVHGFPEFWYSWRHQIKEFSKDYWTITIDQRGYGD
SEKPSKISEYHINNMADDIRALVKKLGREKFILIAHDWGAAVGFNYVYRYMDTIEKYVMI
GGPPSEAWKKLIVSSPKQFIMSWYIFFFQMPWLPEFVIRCNDLKSFDTMRLGSKEDVECF
KYTFSKPGALTSPINYYRAIKVLNPDPPLKKPANCAPGLFLLGEYDKYIARSTGKLAKAE
LDNLDFKLIMSANHFAQQHKPEETNRMIREFLDKKMQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g13377.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 60 | 333 | 8.3E-74 |
| 2 | g13377.t1 | PANTHER | PTHR43329 | EPOXIDE HYDROLASE | 19 | 333 | 2.5E-80 |
| 3 | g13377.t1 | PANTHER | PTHR43329:SF17 | EPOXIDE HYDROLASE 1 | 19 | 333 | 2.5E-80 |
| 7 | g13377.t1 | PRINTS | PR00412 | Epoxide hydrolase signature | 88 | 106 | 3.4E-15 |
| 5 | g13377.t1 | PRINTS | PR00412 | Epoxide hydrolase signature | 153 | 166 | 3.4E-15 |
| 6 | g13377.t1 | PRINTS | PR00412 | Epoxide hydrolase signature | 276 | 292 | 3.4E-15 |
| 4 | g13377.t1 | PRINTS | PR00412 | Epoxide hydrolase signature | 309 | 331 | 3.4E-15 |
| 1 | g13377.t1 | Pfam | PF00561 | alpha/beta hydrolase fold | 82 | 198 | 2.2E-22 |
| 12 | g13377.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 11 | - |
| 13 | g13377.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 34 | - |
| 11 | g13377.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 35 | 337 | - |
| 9 | g13377.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 61 | 334 | 6.62E-67 |
| 8 | g13377.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 34 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
- This transcript has been annotated with K22369 (epoxide hydrolase 4 [EC:3.3.-.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
