General information for g1363.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Cathepsin L-like.
Parent gene
- The parent gene g1363 is located on chr_3: 10178411..10183816 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1363 | g1363.t1 | isoform | g1363.t1 | 10178411 | 10183816 |
| chr_3 | g1363 | g1363.t1 | exon | g1363.t1.exon1 | 10178411 | 10178850 |
| chr_3 | g1363 | g1363.t1 | cds | g1363.t1.CDS1 | 10178411 | 10178850 |
| chr_3 | g1363 | g1363.t1 | exon | g1363.t1.exon2 | 10179156 | 10179289 |
| chr_3 | g1363 | g1363.t1 | cds | g1363.t1.CDS2 | 10179156 | 10179289 |
| chr_3 | g1363 | g1363.t1 | exon | g1363.t1.exon3 | 10183716 | 10183816 |
| chr_3 | g1363 | g1363.t1 | cds | g1363.t1.CDS3 | 10183716 | 10183816 |
| chr_3 | g1363 | g1363.t1 | TSS | g1363.t1 | NA | NA |
| chr_3 | g1363 | g1363.t1 | TTS | g1363.t1 | NA | NA |
Sequences
>g1363.t1 Gene=g1363 Length=675
ATGCCAGAAAACAAAGCACAAATGTCCCTTTTCTTTTCCGCCTTCTCAACCTTACCAATA
ACAACAATAAGCGAAAAAGCATTTTTGCGAGGCAGCAGCAGCACCAATAACAAAGAGCCT
TTGACAATTCCTCCATTAAATTATCCTTTATATAATTATACTACTTTCAATGTTCCACCA
AGAGTTGATTGGAATATTTTAATGGAACCAGTTCAAAATCAAGGACTTTGTGGAGAGTCA
AATGAAGATGGAAATGTTGCTCCCAAAACTGACGAATATCCTTATCAGATGAAGAAGAAC
AATTGTAAGAAAAGTGTTCAATTAAATTTAACGAAAGTCATTCAAAAGTTTACAAATGGC
AATGAATCATTATTGCAAGCTCAAGTAACCAATTATGGACCAACAATTGGTGTTTTTTAT
GTAATACATTCTTTTCTTACTCTTGGAAATGGTGTTTTTAAAGATTCAACTTGTCCAACT
GGCACTCTTGCTTGTAATGTTGTGCAACATTCGATATTAATTGTTGGTTATGGCACTGAT
GAAATTGAAGGAAATCATTGGCTTGTAAAGAATTCGTGGGGCATTTCCTGGGGTCAAAAT
GGTTATGGAAGAATTGCGAGAAATCAGAATAATATGTGTGGCTTGTTGGGGAATCAATGC
TTTTTAATGATATAA
>g1363.t1 Gene=g1363 Length=224
MPENKAQMSLFFSAFSTLPITTISEKAFLRGSSSTNNKEPLTIPPLNYPLYNYTTFNVPP
RVDWNILMEPVQNQGLCGESNEDGNVAPKTDEYPYQMKKNNCKKSVQLNLTKVIQKFTNG
NESLLQAQVTNYGPTIGVFYVIHSFLTLGNGVFKDSTCPTGTLACNVVQHSILIVGYGTD
EIEGNHWLVKNSWGISWGQNGYGRIARNQNNMCGLLGNQCFLMI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g1363.t1 | Gene3D | G3DSA:3.90.70.10 | Cysteine proteinases | 82 | 222 | 1.6E-29 |
| 2 | g1363.t1 | PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 91 | 215 | 1.1E-22 |
| 3 | g1363.t1 | PANTHER | PTHR12411:SF734 | CATHEPSIN S, ORTHOLOG 1 | 91 | 215 | 1.1E-22 |
| 1 | g1363.t1 | Pfam | PF00112 | Papain family cysteine protease | 89 | 216 | 9.0E-26 |
| 10 | g1363.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 24 | - |
| 11 | g1363.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 9 | - |
| 12 | g1363.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 10 | 20 | - |
| 13 | g1363.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 21 | 24 | - |
| 9 | g1363.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 25 | 224 | - |
| 7 | g1363.t1 | ProSitePatterns | PS00639 | Eukaryotic thiol (cysteine) proteases histidine active site. | 168 | 178 | - |
| 6 | g1363.t1 | ProSitePatterns | PS00640 | Eukaryotic thiol (cysteine) proteases asparagine active site. | 186 | 205 | - |
| 5 | g1363.t1 | SMART | SM00645 | pept_c1 | 58 | 224 | 7.2E-8 |
| 4 | g1363.t1 | SUPERFAMILY | SSF54001 | Cysteine proteinases | 41 | 214 | 9.49E-33 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008234 | cysteine-type peptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed