Gene loci information

Transcript annotation

  • This transcript has been annotated as Tyrosine aminotransferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13830 g13830.t1 TTS g13830.t1 32622485 32622485
chr_1 g13830 g13830.t1 isoform g13830.t1 32622572 32624031
chr_1 g13830 g13830.t1 exon g13830.t1.exon1 32622572 32622892
chr_1 g13830 g13830.t1 cds g13830.t1.CDS1 32622572 32622892
chr_1 g13830 g13830.t1 exon g13830.t1.exon2 32622954 32623762
chr_1 g13830 g13830.t1 cds g13830.t1.CDS2 32622954 32623762
chr_1 g13830 g13830.t1 exon g13830.t1.exon3 32623835 32623855
chr_1 g13830 g13830.t1 cds g13830.t1.CDS3 32623835 32623855
chr_1 g13830 g13830.t1 exon g13830.t1.exon4 32623929 32624031
chr_1 g13830 g13830.t1 cds g13830.t1.CDS4 32623929 32624031
chr_1 g13830 g13830.t1 TSS g13830.t1 32624127 32624127

Sequences

>g13830.t1 Gene=g13830 Length=1254
ATGACAACGTTTGCCGAAAAAACTGACAATCCGTTGCGAAAAATTTGGGAAGGTCCGAAA
ATTGACCCGAATAAAGATAAGAAATTGATTACATTACAAATTGGAGACCCTACAGCATTT
GGCAATTTTTATGCAGCAAAAGAAAGTATTGAGGCCATAAAAAATGCTCTTGAAAAAGAC
AATTTTTCATACACAGTCAGTTCTGGTTTAAAAGCTGCTAGAGAAGCAGTGGCATCATAT
GTAAACAACAATGATAAAAGTGTTCAGGTCAATGATTCTGACAAATGTTTTGATGTAAAT
TCTGAGGACGTTATAATGTCAAACGGCTGTTCTACTGCATTAGAAATTTGTTTTCGAGCT
CTAGCAAATCCTAGAGAAAATATTTTAGTTCCACGTCCTTCATGGAATTATTCCACATGG
CTAGAACCTACTGAAATTGTGTCTAAATTCTATAATTTAGATTGCACAAGAAATTGGGAA
ATTGATCTAGAACATCTAGAGTCGCAAATAGATGAATCTACTAGAGCAATTTTAGTTAAC
AACCCTGGCAATCCATGTGGAAATGTTTTTAGCAAAGAACATATCCTAAAAATATTAGAA
ATTGCAGAAAAACATCAAATACCAATAATTGCTGATGAGGTTTACGAATTTTTTACATTT
CCTGGTATCGAATTTTACTCATTCAGTTCGCTTTCAAAAAATGTTCCAATTTTAACATGC
TCAGGATTAACAAAAAGATTTATAATGCCCGGAATAAGAGTCGGTTGGATTGTCATTCAT
GATCGAAATAATCAGTTGAATGATATAAGAAAAGGTCTTTTGAATATAGCAGGAAGAAAT
TTTTGGCCCAATTCAACAGCACAAATAGCTTTAACTGAAATCATTAAAAACACACCAAAG
GCATTTCTTGAAGAAAACGCTGCTCGTGTTCATGATCATGCATTATCAGCTTATAAAATA
TTACGAGAAACTCCTGGTTTAATTCCAATATTCCCACGTGGCGGAATGTACATCATGATT
AAAATTGAACTCGAGAAATTTCCAAAATTCAAAACATGTTTAGAGTTTACACAACAATTG
ATAAGGGAGCAAAGCGTTGCAACCTTTCCTGGATATCCGTGCTTCAATTTTCCCGGCTTT
TTTAGAATCGTTTTAACAGTGCCTAAAGAATTAATCATTGAAGCTTGTGAACGTATTAAA
GAATTTTGTGAACAAAATTGCAAGCAAAGTGAAAAATATTTGAAGAGCGGGTAA

>g13830.t1 Gene=g13830 Length=417
MTTFAEKTDNPLRKIWEGPKIDPNKDKKLITLQIGDPTAFGNFYAAKESIEAIKNALEKD
NFSYTVSSGLKAAREAVASYVNNNDKSVQVNDSDKCFDVNSEDVIMSNGCSTALEICFRA
LANPRENILVPRPSWNYSTWLEPTEIVSKFYNLDCTRNWEIDLEHLESQIDESTRAILVN
NPGNPCGNVFSKEHILKILEIAEKHQIPIIADEVYEFFTFPGIEFYSFSSLSKNVPILTC
SGLTKRFIMPGIRVGWIVIHDRNNQLNDIRKGLLNIAGRNFWPNSTAQIALTEIIKNTPK
AFLEENAARVHDHALSAYKILRETPGLIPIFPRGGMYIMIKIELEKFPKFKTCLEFTQQL
IREQSVATFPGYPCFNFPGFFRIVLTVPKELIIEACERIKEFCEQNCKQSEKYLKSG

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g13830.t1 CDD cd00609 AAT_like 34 401 4.82785E-78
7 g13830.t1 Coils Coil Coil 156 176 -
5 g13830.t1 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 31 403 2.0E-113
6 g13830.t1 Gene3D G3DSA:3.40.640.10 - 47 298 2.0E-113
2 g13830.t1 PANTHER PTHR45744 TYROSINE AMINOTRANSFERASE 5 410 1.5E-124
3 g13830.t1 PANTHER PTHR45744:SF2 TYROSINE AMINOTRANSFERASE 5 410 1.5E-124
8 g13830.t1 PIRSF PIRSF000517 Tyr_transaminase 1 417 1.5E-127
1 g13830.t1 Pfam PF00155 Aminotransferase class I and II 28 399 2.0E-57
4 g13830.t1 SUPERFAMILY SSF53383 PLP-dependent transferases 23 405 1.12E-77
10 g13830.t1 TIGRFAM TIGR01265 tyr_nico_aTase: tyrosine/nicotianamine family aminotransferase 4 406 4.5E-128

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009058 biosynthetic process BP
GO:0006520 cellular amino acid metabolic process BP
GO:0008483 transaminase activity MF
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values