General information for g1384.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein toll.
Parent gene
- The parent gene g1384 is located on chr_3: 10404332..10407702 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1384 | g1384.t1 | isoform | g1384.t1 | 10404332 | 10407702 |
| chr_3 | g1384 | g1384.t1 | exon | g1384.t1.exon1 | 10404332 | 10404888 |
| chr_3 | g1384 | g1384.t1 | cds | g1384.t1.CDS1 | 10404332 | 10404888 |
| chr_3 | g1384 | g1384.t1 | exon | g1384.t1.exon2 | 10404972 | 10406437 |
| chr_3 | g1384 | g1384.t1 | cds | g1384.t1.CDS2 | 10404972 | 10406437 |
| chr_3 | g1384 | g1384.t1 | exon | g1384.t1.exon3 | 10406513 | 10407702 |
| chr_3 | g1384 | g1384.t1 | cds | g1384.t1.CDS3 | 10406513 | 10407702 |
| chr_3 | g1384 | g1384.t1 | TSS | g1384.t1 | NA | NA |
| chr_3 | g1384 | g1384.t1 | TTS | g1384.t1 | NA | NA |
Sequences
>g1384.t1 Gene=g1384 Length=3213
ATGACGAAATTTAAAGAGCTTTTGGTGCTTCTGGTTCTCTCTGTTTTTACAGCAACATCA
TCAAAAATTCTAAAATGTCCTGTCAACGATAACGGTTGCCATTGTAGTGAATATGGCGAG
CTTGAAATTCAATGTCCGAAATTTGATCCTAGAATTTTTGTTAAAATTCAACCCAACAAT
TTCCTCAATTTTGAGTGCGAAAACACTCAAGAGGGTGACTACAATTTAGTGCCCGAAATG
GAATTGCCTGAAGCACAAATGATAAAAATTATGAGATGTCCGTTGCCACAACAGAGATCG
TTAGCGACTTACTTCAAAAATATCAAAATTGAGAGAATTTTGTGGCTTCAAATTTTCAGT
GGTGGTGTCAATGGCCATAGCTCGCTACGACAAGTGCACTTGAGAGGATTTGAGGACATC
ACGAGATTTCATTTACGTGGCAATGACAACGAATTTCAAGATCTTCCATCAGATTTATTT
GCAAACATGTCAAAGCTCGCTTGGGTGACTATTCGTGTTGGCAACATTCAATTGCCAGTA
GATTTATTTGCACCACTTGAAAATCTCGAGTTTCTTGAGTTAGGACATAATAAAGTTGCC
AATTTAGAGCCAGGCATGTTAAGAAACAATCGAAAATTACAACAATTGAATTTGTGGGGA
AATAACCTAAGAAATCTCGATAAGGAAGCATTCTTTGGCCTTGACAATCTTCGTGAACTG
GATCTTAGTACAAATGGCATGGAGTCACTTGAGCCGGATCTTTTCATGTATCTTACGAGT
CTCACACATTTAAATTTGGGTGGTAATAATTTTGCATCGTTGCCTGAAGGTCTTTTTGCC
AACAATCCTAAACTAACTATTTTTAAAATGCTTGAAAATCGCGTCACAATGGATACATTG
CCAAATGGATTTTTATCAAATTTAACGATGCTTTCGGATGTTTATATCAAATCAGGTCTA
CGTAAAATACCCGAAGACACATTTGAAAATTCAATCAACATTTCAATTATTCGACTTGAT
GGAAATGAGCTTGAAGTGCTGCCAGAAGAACTCTTTATGGATCAAGTTAGATTGAGTAAA
TTGGATTTAAGTAATAATTGGCTCAATGAATTACCATTACAAATATTTGCAAATACAAGA
GATTTAAAAGAATTGAGGTTAAATAACAATCGATTGTCCAAACTTCCATCGCAAATATTT
CAACGTCTTGGAAAGCTCACAGAACTTCATCTTGATAACAATCAGCTTGTGTCTCTTCCC
TCTGGCATTTTTGAAAGTCTTAAAGCACTCCGTTCTCTTGATCTCTCAAACAATGGTTTA
AGATTTGAAATGCAATTTGGAGGAAACTTTAGTGATTCAATTCCTGTTTCATCGCGTTTT
CAAGGACTCGAAAGTCTCGAAGAATTGAATTTGCGTAATAATTCAATCACAAGTATCTTT
GAAGATTTTACACTACAAAGTTTAAAATATGTTGACATGAGTCATAATAAAATGACAAGT
TTATTGAGAATTGATCTACAGTTTAGTTCACGATCGCCAATAACGGTTGATTTAAGTAAC
AATCAAATTGAACACATTGAATTTTCACCAAAAGATGATGAACTTTTGTCAAGTCAGACA
CAAGTCAATTTAATGCTGGCTCACAATCCAATCATTTGTGATTGTCAACTTTTACATTTT
GTTAAATTTCTTCAAAATGAAAATCGTGAAAAGAGCAACATTAAAGTTCAATCGGGTGAA
ATGAAATGTGCTATGCCAGAAAGAATGCAAGGTCGTGAATTGACTTCAATAAACGCTCTT
GAATTACTCTGTCCATTAGATGATGCTAGCAGCACAAAAGAAAAGAGATGTCCTGCAGCT
TGCATTTCATGCGATATCAGACGAGAAGACAAGACTTTATTAATGAATTGTTTGGGAAAT
GTTAGCATGTCATCATTACCTAAAATATCAGAATCTGACTTAGACCATCTTGAATTAAGA
ATGGAAAAACAAAATATCACAGAACTGCCAGGAAGTGATAATCCTGGATATCAGCAAATT
ACAAAACTTTATGTCAATGACAACAATATTAAATACATTGGTGAATTGCCAAAAAATCTC
GTCGTTCTTGAACTTGAAAATAATCAAATTGAATCTCTCAATGATTCAGTAATTGATGCA
CTTAATAATTCACAAACATTGCAATCATTAAAATTAAGTGGCAATCCATGGAAATGTGAC
TGTGATTTTGTCAAAATGCTCAACTTTTTGCAGAAATTTTACAAAAATATAACAGATTAC
AGTGAAATGATGTGCACAGATGGTCAATTTATCAATCAACTTTCAGCCAGTGCTCTTTGT
TCAGAAGATAAACTTCTCATTGTTATTGCAAGCATCATATTAGCAATTTTGAGTTTAGTG
ATTGGCGTGTTAGCTGCTCTCTATTACAAATATCAGAAACAAATCAAAATGTGGCTTTAT
TCACACAATATGTGCTTATGGTTTGTTACTGAAGAAGAATTAGATAAGGATAAAACTTAT
GATGCTTTTGTGTCATATGCACATCAAGATGGAGACTTTATTACAGATCAACTTGTGCCA
CATCTTGAAAATTGTGTAGTTCCATATAAATTATGTTTGCACGAACGAGACTGGTCGCCT
GGTTTAGAAATTAGCACACAAATCTCAAACTCTATCAATGACTCAAAACGTACAATTGTT
GTCATGTCACCGCATTATCTAAATTCAAATTGGGCGCAATGGGAATTCCGAGTTGCACAA
TCGCATGCGGCAACAGAAAAGCGTTCTCGTATCATTGTCATACTCTATGGCGACATTGGT
GACATTAACAAATTAGAGCCCGACATTCGAGATTACTTGAAGCTCAACACTTATGTGAAA
TGGGGAGACAAATGGTTTTGGGAAAAATTACGTTATGCGATGCCTCATGTTAAGGGTCAA
GGGCCACTAGACAAGTCGAAAGGCTTAGTAAAAACTGCCATCAAGAGTTCAGTCGATGAC
AAATTAGAGCTCATTAAGCCAGTATCAGTGACGCCGCCTCAATTGACAACGCCACCAGCA
GAACAGATCGCAAATCCCCTCATTACGAAGCTCAATGCAAAGAATGCAGCCAAGACTCAA
CAACATCATCAGAATGGAGGATTGAATGGATATAACGGACACATTAATGGAGCTTATGTT
ATCAATACAAGCTCACGTCAGAGCGATGTCTGA
>g1384.t1 Gene=g1384 Length=1070
MTKFKELLVLLVLSVFTATSSKILKCPVNDNGCHCSEYGELEIQCPKFDPRIFVKIQPNN
FLNFECENTQEGDYNLVPEMELPEAQMIKIMRCPLPQQRSLATYFKNIKIERILWLQIFS
GGVNGHSSLRQVHLRGFEDITRFHLRGNDNEFQDLPSDLFANMSKLAWVTIRVGNIQLPV
DLFAPLENLEFLELGHNKVANLEPGMLRNNRKLQQLNLWGNNLRNLDKEAFFGLDNLREL
DLSTNGMESLEPDLFMYLTSLTHLNLGGNNFASLPEGLFANNPKLTIFKMLENRVTMDTL
PNGFLSNLTMLSDVYIKSGLRKIPEDTFENSINISIIRLDGNELEVLPEELFMDQVRLSK
LDLSNNWLNELPLQIFANTRDLKELRLNNNRLSKLPSQIFQRLGKLTELHLDNNQLVSLP
SGIFESLKALRSLDLSNNGLRFEMQFGGNFSDSIPVSSRFQGLESLEELNLRNNSITSIF
EDFTLQSLKYVDMSHNKMTSLLRIDLQFSSRSPITVDLSNNQIEHIEFSPKDDELLSSQT
QVNLMLAHNPIICDCQLLHFVKFLQNENREKSNIKVQSGEMKCAMPERMQGRELTSINAL
ELLCPLDDASSTKEKRCPAACISCDIRREDKTLLMNCLGNVSMSSLPKISESDLDHLELR
MEKQNITELPGSDNPGYQQITKLYVNDNNIKYIGELPKNLVVLELENNQIESLNDSVIDA
LNNSQTLQSLKLSGNPWKCDCDFVKMLNFLQKFYKNITDYSEMMCTDGQFINQLSASALC
SEDKLLIVIASIILAILSLVIGVLAALYYKYQKQIKMWLYSHNMCLWFVTEEELDKDKTY
DAFVSYAHQDGDFITDQLVPHLENCVVPYKLCLHERDWSPGLEISTQISNSINDSKRTIV
VMSPHYLNSNWAQWEFRVAQSHAATEKRSRIIVILYGDIGDINKLEPDIRDYLKLNTYVK
WGDKWFWEKLRYAMPHVKGQGPLDKSKGLVKTAIKSSVDDKLELIKPVSVTPPQLTTPPA
EQIANPLITKLNAKNAAKTQQHHQNGGLNGYNGHINGAYVINTSSRQSDV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g1384.t1 | Coils | Coil | Coil | 703 | 723 | - |
| 19 | g1384.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 23 | 417 | 2.0E-82 |
| 20 | g1384.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 453 | 508 | 1.8E-7 |
| 18 | g1384.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 509 | 602 | 8.1E-12 |
| 21 | g1384.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 603 | 785 | 1.8E-32 |
| 17 | g1384.t1 | Gene3D | G3DSA:3.40.50.10140 | - | 829 | 979 | 1.1E-46 |
| 7 | g1384.t1 | PANTHER | PTHR24365 | TOLL-LIKE RECEPTOR | 127 | 282 | 6.1E-99 |
| 6 | g1384.t1 | PANTHER | PTHR24365 | TOLL-LIKE RECEPTOR | 320 | 450 | 6.1E-99 |
| 5 | g1384.t1 | PANTHER | PTHR24365 | TOLL-LIKE RECEPTOR | 420 | 612 | 6.1E-99 |
| 4 | g1384.t1 | PANTHER | PTHR24365 | TOLL-LIKE RECEPTOR | 644 | 974 | 6.1E-99 |
| 9 | g1384.t1 | PRINTS | PR01537 | Interleukin-1 receptor type I family signature | 792 | 820 | 2.7E-9 |
| 11 | g1384.t1 | PRINTS | PR01537 | Interleukin-1 receptor type I family signature | 852 | 876 | 2.7E-9 |
| 8 | g1384.t1 | PRINTS | PR01537 | Interleukin-1 receptor type I family signature | 877 | 904 | 2.7E-9 |
| 10 | g1384.t1 | PRINTS | PR01537 | Interleukin-1 receptor type I family signature | 959 | 978 | 2.7E-9 |
| 2 | g1384.t1 | Pfam | PF13855 | Leucine rich repeat | 211 | 271 | 3.5E-15 |
| 1 | g1384.t1 | Pfam | PF13855 | Leucine rich repeat | 381 | 440 | 1.3E-12 |
| 3 | g1384.t1 | Pfam | PF01582 | TIR domain | 842 | 985 | 2.3E-21 |
| 25 | g1384.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 26 | g1384.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 27 | g1384.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 16 | - |
| 29 | g1384.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 21 | - |
| 24 | g1384.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 784 | - |
| 28 | g1384.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 785 | 809 | - |
| 23 | g1384.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 810 | 1070 | - |
| 63 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 188 | 209 | 6.287 |
| 68 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 212 | 233 | 6.919 |
| 64 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 236 | 257 | 7.519 |
| 59 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 260 | 281 | 7.073 |
| 61 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 333 | 354 | 5.063 |
| 71 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 357 | 378 | 6.749 |
| 67 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 381 | 402 | 7.62 |
| 73 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 405 | 426 | 7.543 |
| 72 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 429 | 441 | 5.155 |
| 66 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 465 | 486 | 8.351 |
| 70 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 487 | 508 | 5.841 |
| 69 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 512 | 533 | 5.24 |
| 60 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 679 | 698 | 5.579 |
| 62 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 699 | 720 | 6.626 |
| 65 | g1384.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 726 | 747 | 4.678 |
| 74 | g1384.t1 | ProSiteProfiles | PS50104 | TIR domain profile. | 838 | 977 | 34.588 |
| 40 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 186 | 209 | 0.38 |
| 55 | g1384.t1 | SMART | SM00365 | LRR_sd22_2 | 186 | 204 | 61.0 |
| 48 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 211 | 233 | 12.0 |
| 46 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 234 | 257 | 0.76 |
| 52 | g1384.t1 | SMART | SM00365 | LRR_sd22_2 | 234 | 255 | 88.0 |
| 34 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 258 | 277 | 98.0 |
| 49 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 258 | 281 | 3.7E-5 |
| 38 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 331 | 350 | 350.0 |
| 42 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 332 | 354 | 240.0 |
| 35 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 355 | 374 | 280.0 |
| 47 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 356 | 378 | 9.0 |
| 32 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 379 | 398 | 82.0 |
| 41 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 379 | 402 | 1.2 |
| 33 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 403 | 422 | 6.8 |
| 50 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 403 | 426 | 1.3E-5 |
| 39 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 427 | 448 | 89.0 |
| 36 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 463 | 482 | 290.0 |
| 45 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 463 | 482 | 10.0 |
| 51 | g1384.t1 | SMART | SM00365 | LRR_sd22_2 | 463 | 484 | 280.0 |
| 43 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 485 | 508 | 110.0 |
| 53 | g1384.t1 | SMART | SM00365 | LRR_sd22_2 | 485 | 506 | 400.0 |
| 57 | g1384.t1 | SMART | SM00082 | lrrct1 | 549 | 605 | 1.5E-7 |
| 37 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 677 | 696 | 470.0 |
| 44 | g1384.t1 | SMART | SM00369 | LRR_typ_2 | 696 | 720 | 98.0 |
| 31 | g1384.t1 | SMART | SM00364 | LRR_bac_2 | 697 | 716 | 150.0 |
| 54 | g1384.t1 | SMART | SM00365 | LRR_sd22_2 | 697 | 715 | 110.0 |
| 56 | g1384.t1 | SMART | SM00082 | lrrct1 | 735 | 781 | 1.3 |
| 58 | g1384.t1 | SMART | SM00255 | till_3 | 839 | 977 | 1.0E-34 |
| 14 | g1384.t1 | SUPERFAMILY | SSF52058 | L domain-like | 150 | 556 | 5.83E-55 |
| 13 | g1384.t1 | SUPERFAMILY | SSF52058 | L domain-like | 645 | 769 | 6.23E-16 |
| 12 | g1384.t1 | SUPERFAMILY | SSF52200 | Toll/Interleukin receptor TIR domain | 829 | 978 | 6.28E-44 |
| 16 | g1384.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 15 | g1384.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 25 | - |
| 30 | g1384.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 786 | 808 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
| GO:0005515 | protein binding | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0006955 | immune response | BP |
| GO:0004888 | transmembrane signaling receptor activity | MF |
| GO:0002224 | toll-like receptor signaling pathway | BP |
KEGG
Orthology
- This transcript has been annotated with K18809 (protein toll)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
