Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Kynurenine formamidase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g13991 g13991.t1 TSS g13991.t1 33860855 33860855
chr_1 g13991 g13991.t1 isoform g13991.t1 33860882 33861825
chr_1 g13991 g13991.t1 exon g13991.t1.exon1 33860882 33860990
chr_1 g13991 g13991.t1 cds g13991.t1.CDS1 33860882 33860990
chr_1 g13991 g13991.t1 exon g13991.t1.exon2 33861065 33861825
chr_1 g13991 g13991.t1 cds g13991.t1.CDS2 33861065 33861825
chr_1 g13991 g13991.t1 TTS g13991.t1 33861850 33861850

Sequences

>g13991.t1 Gene=g13991 Length=870
ATGAGCTCCGTTGAAGATCTTGAAACAAAATATACACCATCTTTTTTTACCAAAAGATTC
TCAACATCCGAAGAATTGTTGAAAAATTTCATAACTGTTACTAATAAGGAATCCGAAAAA
AATCGATTAAATTATGATTGTCATTTAAATATCGCATATGGACCAACTAAACGTGAAAAA
CTCGATATTTATGGCGATGATCTTCCGAAATCTGCTCCTCTTTTTGTTTTTATACATGGC
GGCTATTGGAGGCAAGTTGACAAAGAGGGATCAGCATTTATGGTTAAACCACTATATGAA
AACGGAATACGAGTCATAACGATCGACTACGAATTGTGCCCAAATGTGACTCTTGAAGAA
ATTGTTGAGCAGGTTAAAAAATGTTTTAAATGGATTGCTCAGTACATAAAACAAAACGAG
ATAAGAAAAGTTGCCCTATCGGGTCACTGTGTTGGAGCACATTTACTTTGTTATGGAATT
ATTGAAGAATTTATGGAAACAATATCTTCTTCTGTTGAACTTCATGCGTTTTTCTTTTCC
GGAGTGTACTATCTTGAAGAATTGAGATATTTAAAGTCTACTAATGAAAATAACATCTTG
CATATTACTGATGAAAACTGTCGTCGTCTTTCACCACAATACATCGATTTCAACTATTTG
AAACATTTCAATTTTCATGCTCATGTGTTTGCTGGTGAATTTGAATCAGAAAAATTTCAT
GAGCATTCAAAAAAATTTGCAGAAGGTCCAATGAAAGACTTTTTAAAAACTTTTAAAATT
TTTGAAAAACTTGATCATTTTGATTTAGTTGAAAACATGTATGAAAGTAATTATGAGCTC
ACAAAACTAATCATTGAATGTCTCAAATAA

>g13991.t1 Gene=g13991 Length=289
MSSVEDLETKYTPSFFTKRFSTSEELLKNFITVTNKESEKNRLNYDCHLNIAYGPTKREK
LDIYGDDLPKSAPLFVFIHGGYWRQVDKEGSAFMVKPLYENGIRVITIDYELCPNVTLEE
IVEQVKKCFKWIAQYIKQNEIRKVALSGHCVGAHLLCYGIIEEFMETISSSVELHAFFFS
GVYYLEELRYLKSTNENNILHITDENCRRLSPQYIDFNYLKHFNFHAHVFAGEFESEKFH
EHSKKFAEGPMKDFLKTFKIFEKLDHFDLVENMYESNYELTKLIIECLK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g13991.t1 Gene3D G3DSA:3.40.50.1820 - 31 286 0.0e+00
2 g13991.t1 PANTHER PTHR23024 ARYLACETAMIDE DEACETYLASE 33 267 0.0e+00
3 g13991.t1 PANTHER PTHR23024:SF554 KYNURENINE FORMAMIDASE 33 267 0.0e+00
1 g13991.t1 Pfam PF07859 alpha/beta hydrolase fold 76 160 1.3e-05
4 g13991.t1 SUPERFAMILY SSF53474 alpha/beta-Hydrolases 40 288 0.0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016787 hydrolase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values