General information for g14017.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Branched-chain-amino-acid aminotransferase.
Parent gene
- The parent gene g14017 is located on chr_1: 34092319..34093211 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14017 | g14017.t1 | TSS | g14017.t1 | 34086713 | 34086713 |
| chr_1 | g14017 | g14017.t1 | isoform | g14017.t1 | 34086920 | 34092502 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon1 | 34086920 | 34086937 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS1 | 34086920 | 34086937 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon2 | 34090507 | 34090731 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS2 | 34090507 | 34090731 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon3 | 34090903 | 34091112 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS3 | 34090903 | 34091112 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon4 | 34091460 | 34092003 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS4 | 34091460 | 34092003 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon5 | 34092066 | 34092220 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS5 | 34092066 | 34092220 |
| chr_1 | g14017 | g14017.t1 | exon | g14017.t1.exon6 | 34092314 | 34092502 |
| chr_1 | g14017 | g14017.t1 | cds | g14017.t1.CDS6 | 34092314 | 34092502 |
| chr_1 | g14017 | g14017.t1 | TTS | g14017.t1 | 34093207 | 34093207 |
Sequences
>g14017.t1 Gene=g14017 Length=1341
ATGAGCATTCACGGCAAGACAATGCTACCTTACATTGTAAGGAAAGTCTTTGAAATCCAA
CATAAACTATATCAGCAACAAATTCGTGCATGCAGCACTGGTCGATTGCAAGAAGCATTA
AAGATCGAAGAAGAGCAAGAATTTCCAAAAATCAATGAAATCAAGCAGCCTGAAGAGTCG
TCATTTTACTATCCTGTCGACAAGAAATTCAAACACGACCCCGATATCGGAGAACAATTT
TCATATTCACAATTGCGTGTTCGTTTGGCGGGACCTCATCAATTGCAACCTAAACCTGAA
GCTGATGATCTGCAGTTTGGAAAACTCTTTACTGATCATATGTTTAAAGTCGCTTACCAT
AAGCGTCTGGGTGGTTGGCAAGTACCCGAAATTATGCCACTCGAAAATCTTGTTTTACAT
CCTGCAGCTAAAGTTTTACATTATGCTGTTGAGCTGTTTGAAGGCATGAAAGCATTCAGA
GGCGTTGATGGGCGTATTCGTCTATTCCGACCTGAAATGAATATGGCTCGAATGAATGCA
AGTGCACAACGCTCAGGTCTCCCCACTTTTGAACCTGAAGAATTTGTTAAATGCATTTCA
AGACTCGTCTCAATTGACCAGGAATGGGTGCCGCATACAGAATCTGCAAGCTTATACATT
CGACCAACACTTATTGGAATTGAACCAACTCTTGGTGTTGCATCGTCTGAATCAGCACTA
TTGTATACGATTTTGTCACCTGTTGGTGGATATTTTGCGGGAAATAGTGGCACATCAACT
GGTGTTTCTTTATTAGCAGATCCTCAATATACGAGATCATGGCCGGGTGGAGTTGGTGAT
AGAAAAATGGGCTCAAACTATGCACCAACTATTCATGTGCAAAAAGAAGCTTCTAAACAA
GGTTTTCAACAAGTATTGTGGTTATATGGTGATGATCATCAACTAACAGAAGTTGGTACA
ATGAACATTTTTGTTCTATTAATTAATGATCGTGGAGAACGTGAACTTGTTACACCACCA
TTAAATGGTTTAATTTTACCTGGAATTGTTCGTCACTCAATTCTCAATCTTGCTCGCGAA
TGGAATCAAGTTAAAGTGACTGAACGTAAAATCACAATGGCTGAAGTTAAGAAACTAGTC
TATGAAAATAGAGTTCTCGAAATGTTTGGTGCTGGAACAGCATGTGTTGTATCACCTATC
GAAAGAATCTTTTACATGAACGAGAATTTGCTCATTCCAACGATGGAGAATAGTGATGCA
GTATGGCGTACAATGCGCAATACCCTTCTCGACATTCAATATGGTCGAGTTAAGCATCCT
TGGGCAATAGAAATTGATTAA
>g14017.t1 Gene=g14017 Length=446
MSIHGKTMLPYIVRKVFEIQHKLYQQQIRACSTGRLQEALKIEEEQEFPKINEIKQPEES
SFYYPVDKKFKHDPDIGEQFSYSQLRVRLAGPHQLQPKPEADDLQFGKLFTDHMFKVAYH
KRLGGWQVPEIMPLENLVLHPAAKVLHYAVELFEGMKAFRGVDGRIRLFRPEMNMARMNA
SAQRSGLPTFEPEEFVKCISRLVSIDQEWVPHTESASLYIRPTLIGIEPTLGVASSESAL
LYTILSPVGGYFAGNSGTSTGVSLLADPQYTRSWPGGVGDRKMGSNYAPTIHVQKEASKQ
GFQQVLWLYGDDHQLTEVGTMNIFVLLINDRGERELVTPPLNGLILPGIVRHSILNLARE
WNQVKVTERKITMAEVKKLVYENRVLEMFGAGTACVVSPIERIFYMNENLLIPTMENSDA
VWRTMRNTLLDIQYGRVKHPWAIEID
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g14017.t1 | CDD | cd01557 | BCAT_beta_family | 139 | 435 | 1.03897E-123 |
| 4 | g14017.t1 | Gene3D | G3DSA:3.30.470.10 | - | 103 | 441 | 4.6E-147 |
| 5 | g14017.t1 | Gene3D | G3DSA:3.20.10.10 | - | 252 | 433 | 4.6E-147 |
| 2 | g14017.t1 | PANTHER | PTHR11825 | SUBGROUP IIII AMINOTRANSFERASE | 70 | 445 | 6.7E-161 |
| 6 | g14017.t1 | PIRSF | PIRSF006468 | BCAT1 | 80 | 446 | 4.3E-124 |
| 1 | g14017.t1 | Pfam | PF01063 | Amino-transferase class IV | 152 | 403 | 7.4E-29 |
| 8 | g14017.t1 | ProSitePatterns | PS00770 | Aminotransferases class-IV signature. | 317 | 351 | - |
| 3 | g14017.t1 | SUPERFAMILY | SSF56752 | D-aminoacid aminotransferase-like PLP-dependent enzymes | 92 | 442 | 1.96E-102 |
| 9 | g14017.t1 | TIGRFAM | TIGR01123 | ilvE_II: branched-chain amino acid aminotransferase | 126 | 441 | 4.7E-86 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004084 | branched-chain-amino-acid transaminase activity | MF |
| GO:0009081 | branched-chain amino acid metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00826 (branched-chain amino acid aminotransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
