Gene loci information

Transcript annotation

  • This transcript has been annotated as Branched-chain-amino-acid aminotransferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g14017 g14017.t9 isoform g14017.t9 34090724 34092502
chr_1 g14017 g14017.t9 exon g14017.t9.exon1 34090724 34090731
chr_1 g14017 g14017.t9 exon g14017.t9.exon2 34090903 34091112
chr_1 g14017 g14017.t9 cds g14017.t9.CDS1 34090999 34091112
chr_1 g14017 g14017.t9 exon g14017.t9.exon3 34091460 34092003
chr_1 g14017 g14017.t9 cds g14017.t9.CDS2 34091460 34092003
chr_1 g14017 g14017.t9 exon g14017.t9.exon4 34092066 34092220
chr_1 g14017 g14017.t9 cds g14017.t9.CDS3 34092066 34092220
chr_1 g14017 g14017.t9 exon g14017.t9.exon5 34092314 34092502
chr_1 g14017 g14017.t9 cds g14017.t9.CDS4 34092314 34092502
chr_1 g14017 g14017.t9 TTS g14017.t9 34093207 34093207
chr_1 g14017 g14017.t9 TSS g14017.t9 NA NA

Sequences

>g14017.t9 Gene=g14017 Length=1106
AATTTTCATATTCACAATTGCGTGTTCGTTTGGCGGGACCTCATCAATTGCAACCTAAAC
CTGAAGCTGATGATCTGCAGTTTGGAAAACTCTTTACTGATCATATGTTTAAAGTCGCTT
ACCATAAGCGTCTGGGTGGTTGGCAAGTACCCGAAATTATGCCACTCGAAAATCTTGTTT
TACATCCTGCAGCTAAAGTTTTACATTATGCTGTTGAGCTGTTTGAAGGCATGAAAGCAT
TCAGAGGCGTTGATGGGCGTATTCGTCTATTCCGACCTGAAATGAATATGGCTCGAATGA
ATGCAAGTGCACAACGCTCAGGTCTCCCCACTTTTGAACCTGAAGAATTTGTTAAATGCA
TTTCAAGACTCGTCTCAATTGACCAGGAATGGGTGCCGCATACAGAATCTGCAAGCTTAT
ACATTCGACCAACACTTATTGGAATTGAACCAACTCTTGGTGTTGCATCGTCTGAATCAG
CACTATTGTATACGATTTTGTCACCTGTTGGTGGATATTTTGCGGGAAATAGTGGCACAT
CAACTGGTGTTTCTTTATTAGCAGATCCTCAATATACGAGATCATGGCCGGGTGGAGTTG
GTGATAGAAAAATGGGCTCAAACTATGCACCAACTATTCATGTGCAAAAAGAAGCTTCTA
AACAAGGTTTTCAACAAGTATTGTGGTTATATGGTGATGATCATCAACTAACAGAAGTTG
GTACAATGAACATTTTTGTTCTATTAATTAATGATCGTGGAGAACGTGAACTTGTTACAC
CACCATTAAATGGTTTAATTTTACCTGGAATTGTTCGTCACTCAATTCTCAATCTTGCTC
GCGAATGGAATCAAGTTAAAGTGACTGAACGTAAAATCACAATGGCTGAAGTTAAGAAAC
TAGTCTATGAAAATAGAGTTCTCGAAATGTTTGGTGCTGGAACAGCATGTGTTGTATCAC
CTATCGAAAGAATCTTTTACATGAACGAGAATTTGCTCATTCCAACGATGGAGAATAGTG
ATGCAGTATGGCGTACAATGCGCAATACCCTTCTCGACATTCAATATGGTCGAGTTAAGC
ATCCTTGGGCAATAGAAATTGATTAA

>g14017.t9 Gene=g14017 Length=333
MFKVAYHKRLGGWQVPEIMPLENLVLHPAAKVLHYAVELFEGMKAFRGVDGRIRLFRPEM
NMARMNASAQRSGLPTFEPEEFVKCISRLVSIDQEWVPHTESASLYIRPTLIGIEPTLGV
ASSESALLYTILSPVGGYFAGNSGTSTGVSLLADPQYTRSWPGGVGDRKMGSNYAPTIHV
QKEASKQGFQQVLWLYGDDHQLTEVGTMNIFVLLINDRGERELVTPPLNGLILPGIVRHS
ILNLAREWNQVKVTERKITMAEVKKLVYENRVLEMFGAGTACVVSPIERIFYMNENLLIP
TMENSDAVWRTMRNTLLDIQYGRVKHPWAIEID

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g14017.t9 CDD cd01557 BCAT_beta_family 26 322 2.14177E-124
4 g14017.t9 Gene3D G3DSA:3.30.470.10 - 1 328 3.9E-141
5 g14017.t9 Gene3D G3DSA:3.20.10.10 - 139 320 3.9E-141
2 g14017.t9 PANTHER PTHR11825 SUBGROUP IIII AMINOTRANSFERASE 1 332 3.1E-151
6 g14017.t9 PIRSF PIRSF006468 BCAT1 1 333 1.4E-120
1 g14017.t9 Pfam PF01063 Amino-transferase class IV 39 290 3.1E-29
8 g14017.t9 ProSitePatterns PS00770 Aminotransferases class-IV signature. 204 238 -
3 g14017.t9 SUPERFAMILY SSF56752 D-aminoacid aminotransferase-like PLP-dependent enzymes 10 329 1.03E-97
9 g14017.t9 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 13 328 1.7E-86

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004084 branched-chain-amino-acid transaminase activity MF
GO:0009081 branched-chain amino acid metabolic process BP
GO:0003824 catalytic activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values