Gene loci information

Transcript annotation

  • This transcript has been annotated as Carnitine O-palmitoyltransferase 1, liver isoform.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g14120 g14120.t12 isoform g14120.t12 34807828 34809740
chr_1 g14120 g14120.t12 exon g14120.t12.exon1 34807828 34807887
chr_1 g14120 g14120.t12 cds g14120.t12.CDS1 34807844 34807887
chr_1 g14120 g14120.t12 exon g14120.t12.exon2 34808140 34808199
chr_1 g14120 g14120.t12 cds g14120.t12.CDS2 34808140 34808199
chr_1 g14120 g14120.t12 exon g14120.t12.exon3 34808406 34808544
chr_1 g14120 g14120.t12 cds g14120.t12.CDS3 34808406 34808544
chr_1 g14120 g14120.t12 exon g14120.t12.exon4 34808611 34809136
chr_1 g14120 g14120.t12 cds g14120.t12.CDS4 34808611 34809136
chr_1 g14120 g14120.t12 exon g14120.t12.exon5 34809200 34809740
chr_1 g14120 g14120.t12 cds g14120.t12.CDS5 34809200 34809396
chr_1 g14120 g14120.t12 TTS g14120.t12 34809736 34809736
chr_1 g14120 g14120.t12 TSS g14120.t12 NA NA

Sequences

>g14120.t12 Gene=g14120 Length=1326
GGCGGATGCACCAATAATGGCTCACATTTGGGAACATATTGTTCTTGAAGAGGCAAAACG
GGCTGATGCACCAGTGCTTGGCCACGTTTGGGAATGTGCTCTCGCTGATGATCATGAAGG
ATATGATGAAAATGGTAATACTCTAGGAAAAATTGAAGTTCTTCCACCAGTACCTACACG
ACTTTCGTGGGATTTCAATGACGAATCTTTAGTGAAGACAATTGATATGGCTTATGATGA
TGCACAGAGAATAATCAATGATGTTGATTTGAGAATCCTTGTACATGATGCATATGGCAA
AGGATTTATGAAAACATGTCGTTGTTCACCAGATGCTTTCATTCAAATGGCACTTCAACT
TGCTTATTATCGTGATTATGGAAAATTTTCACTCACATATGAAGCATCAATGACACGATT
GTTCAGAGAAGGTAGAACTGAGACAGTTCGTCCTTGTACAATTGAATCTGCAGCATGGGT
AAAGGCCATGGAAAATAAAGATGTTACAGCTACTGAAAGAGTGAAACTTTTATATGATGC
ATGCAAAAGACATCAGCAAGGATATCAAGATGCTATGTGTGGACGAGGAGTTGACCGTCA
TCTTTTCTGCCTCTATGTTGTTTCAAAATATTTGGAAGTTGATTCACCTTTCTTGAAAGA
AATCTTGAGTGAACCATGGAGACTTTCAACTTCACAAACACCTCATGGACAAACTCCGAA
AATGGATCCAAAGAAAAATCCACACTTTATTAGTGCTGGTGGCGGCTTTGGACCTGTCAG
CGTTGATGGTTATGGTGTTTCATACATAATCGCAGGCGAAGATTTAATATTTTTCCACAT
ATCCAGCCTTAAGAGCTGTAATGTCACAGATTCAGAGAGATTTGCACAGCAAATTTGTAA
AGCATTAACAGACATAAAGTTGCTATTTGAGCAATATAATCTAGAACAGAAGAAAATTCT
ACAGAATGGTACATCACATTAGGACTTTAATTTTAGATTCGCATTAATTGAATATCGTCT
AATCTAGTTATTTTTAATTATATACACATTCTACAATGTTACCAGAGATAAATTCAATGC
AATTTTTATCATCGTAATTGAAAATTTAAGACTCTTAATGTCTATTTTAAAAGAAAGGTA
AAAAGTTTGACAATGTTTGGATTGGGATAGAATTTTGGATGCAATTTAATGTAGAATGAA
AAAGTTTTTAGTACAATGTTGGAACAGATTAGCTTATGTAAATGCGATATGCAATTATCA
ATGCAAACGATATTTGTTTTAACTTTATTGTAAAATTTATATTAAATAAAACAATTAAAA
ATTAAA

>g14120.t12 Gene=g14120 Length=321
MAHIWEHIVLEEAKRADAPVLGHVWECALADDHEGYDENGNTLGKIEVLPPVPTRLSWDF
NDESLVKTIDMAYDDAQRIINDVDLRILVHDAYGKGFMKTCRCSPDAFIQMALQLAYYRD
YGKFSLTYEASMTRLFREGRTETVRPCTIESAAWVKAMENKDVTATERVKLLYDACKRHQ
QGYQDAMCGRGVDRHLFCLYVVSKYLEVDSPFLKEILSEPWRLSTSQTPHGQTPKMDPKK
NPHFISAGGGFGPVSVDGYGVSYIIAGEDLIFFHISSLKSCNVTDSERFAQQICKALTDI
KLLFEQYNLEQKKILQNGTSH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g14120.t12 Gene3D G3DSA:3.30.559.40 - 60 311 0
2 g14120.t12 PANTHER PTHR22589:SF31 CARNITINE PALMITOYLTRANSFERASE I 15 306 0
3 g14120.t12 PANTHER PTHR22589 CARNITINE O-ACYLTRANSFERASE 15 306 0
1 g14120.t12 Pfam PF00755 Choline/Carnitine o-acyltransferase 12 301 0
4 g14120.t12 SUPERFAMILY SSF52777 CoA-dependent acyltransferases 82 308 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values