General information for g14127.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase theta-3.
Parent gene
- The parent gene g14127 is located on chr_1: 34828624..34831172 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14127 | g14127.t1 | isoform | g14127.t1 | 34828624 | 34831172 |
| chr_1 | g14127 | g14127.t1 | exon | g14127.t1.exon1 | 34828624 | 34828922 |
| chr_1 | g14127 | g14127.t1 | cds | g14127.t1.CDS1 | 34828624 | 34828922 |
| chr_1 | g14127 | g14127.t1 | exon | g14127.t1.exon2 | 34830122 | 34830248 |
| chr_1 | g14127 | g14127.t1 | cds | g14127.t1.CDS2 | 34830122 | 34830248 |
| chr_1 | g14127 | g14127.t1 | exon | g14127.t1.exon3 | 34830561 | 34830776 |
| chr_1 | g14127 | g14127.t1 | cds | g14127.t1.CDS3 | 34830561 | 34830776 |
| chr_1 | g14127 | g14127.t1 | exon | g14127.t1.exon4 | 34830902 | 34831025 |
| chr_1 | g14127 | g14127.t1 | cds | g14127.t1.CDS4 | 34830902 | 34831025 |
| chr_1 | g14127 | g14127.t1 | exon | g14127.t1.exon5 | 34831084 | 34831172 |
| chr_1 | g14127 | g14127.t1 | cds | g14127.t1.CDS5 | 34831084 | 34831172 |
| chr_1 | g14127 | g14127.t1 | TSS | g14127.t1 | NA | NA |
| chr_1 | g14127 | g14127.t1 | TTS | g14127.t1 | NA | NA |
Sequences
>g14127.t1 Gene=g14127 Length=855
ATGAATTTTAAAGCAGTGAATAGATTTCAAAAAGTTCCTTGTATTGTTGATGGTGATTTT
CAATTATCTGAGTCGGTGGCAATATTTAGATATTTGATTGAAACAAGAAATGGAGTTGCT
GAAAATTGGTACCCAAAAGAATTAAAGACGAGAGCACTTGTTGATGAGTTTCTTGAGTAT
CAACACAATGCAGTTCGTCTTTCCTTGTGCTATCACGGAGAAAGAATTTTAGCGACAAAA
GAAATTTCTTTTGCTGATGTTTTAGCTGCTTGTGAACTTGAGCAACCGAAAATGGCTGTT
ATTAATACGTTTGAAGGCAGACCAAAATTAACGAAATGGTATGAGCGAGTTAAAGAAGTA
ACCAATCCCTACTATGATGAAGCTCATGTGATTGTTAACAAAGTTATACAAAAGAATAAA
TCAAAAATTGAGCATTCATTTAATTACGACCCAGAGGTTGAAGTTTCTGAAATTAATCAT
GATGTGTTATTTAGAGAAGGAAATTACAACAGAAATGTCACATTTACACCACGAATGTTA
CTTCTAGATTTAAAAGAATTTTTCTCTGATAATCGTTTAACATCAAGAGGATTCTTGAAA
GAATTTCAAAATGATGAGATTAGTCAAGTAAACGAAGTGCCTGTTATGACATCCGTTCAG
AATTCGAATGAGTTATCAAACACATTAGAAAATCTTTATACACAAGTTGAACGCGGTAAA
CTTGCAAAAATTCCACGTTTTATTGATGCTGGCTTAGAGAAAGAAGGATATAAAAGAATT
GCTGGAACAATTACTTGTTTTTTAAAGAACAATATGATGATAACGAATTTTGTAAATTTC
TTTTCAAAATATTAA
>g14127.t1 Gene=g14127 Length=284
MNFKAVNRFQKVPCIVDGDFQLSESVAIFRYLIETRNGVAENWYPKELKTRALVDEFLEY
QHNAVRLSLCYHGERILATKEISFADVLAACELEQPKMAVINTFEGRPKLTKWYERVKEV
TNPYYDEAHVIVNKVIQKNKSKIEHSFNYDPEVEVSEINHDVLFREGNYNRNVTFTPRML
LLDLKEFFSDNRLTSRGFLKEFQNDEISQVNEVPVMTSVQNSNELSNTLENLYTQVERGK
LAKIPRFIDAGLEKEGYKRIAGTITCFLKNNMMITNFVNFFSKY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g14127.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 39 | 0.0000000 |
| 8 | g14127.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 40 | 70 | 0.0000012 |
| 9 | g14127.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 71 | 158 | 0.0000000 |
| 5 | g14127.t1 | PANTHER | PTHR43917 | - | 2 | 68 | 0.0000000 |
| 4 | g14127.t1 | PANTHER | PTHR43917 | - | 74 | 148 | 0.0000000 |
| 3 | g14127.t1 | Pfam | PF02798 | Glutathione S-transferase, N-terminal domain | 3 | 32 | 0.0000560 |
| 2 | g14127.t1 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 73 | 117 | 0.0000590 |
| 1 | g14127.t1 | Pfam | PF10644 | Misato Segment II tubulin-like domain | 144 | 218 | 0.0000000 |
| 12 | g14127.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 1 | 40 | 12.5840000 |
| 11 | g14127.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 2 | 143 | 9.2690000 |
| 6 | g14127.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 2 | 35 | 0.0000000 |
| 7 | g14127.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 42 | 120 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed