General information for g14177.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as DNA polymerase epsilon catalytic subunit 1.
Parent gene
- The parent gene g14177 is located on chr_1: 35244564..35247204 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14177 | g14177.t3 | TTS | g14177.t3 | 35239495 | 35239495 |
| chr_1 | g14177 | g14177.t3 | isoform | g14177.t3 | 35240247 | 35241167 |
| chr_1 | g14177 | g14177.t3 | exon | g14177.t3.exon1 | 35240247 | 35240263 |
| chr_1 | g14177 | g14177.t3 | exon | g14177.t3.exon2 | 35240369 | 35241167 |
| chr_1 | g14177 | g14177.t3 | cds | g14177.t3.CDS1 | 35240399 | 35241136 |
| chr_1 | g14177 | g14177.t3 | TSS | g14177.t3 | 35241257 | 35241257 |
Sequences
>g14177.t3 Gene=g14177 Length=816
TGATGCAGATGATGAAGAACTTGCACTTGAAATGAATTGGAATATTTGTGAAGATTTACC
TGAAGAAGGAAAGTGTCGCGATAAATTGGAAAATTTTCTTACTTTGTTCATTGAACAACT
CGCTGATGGCATTGAATCTTCAAAAGCATTGAAAACTTTATCTCATCATGCATACGATAT
TGTAACGAAATTATATCAGAATTTTGGAAAGAATCAAGAAGGACCAGCAACAGAATTCAT
CAAAGTGCTTTGTAAAATTCTTGAAATTGATACAACAGTGACTGATGAACTTGATTCATT
AAGAAAGAACATGTTAAGACTTGTTGGATTAGGAGAATTTTCAGACAAAGCCGTTTGGAA
AGAGAAAGGAAAATCTTACATTTTAACTGAAATGATTTGTCAAGCTTGTAATCACTGTCG
AGATGTTGATTTGATGAAGGATAAGCATCGTGCTATGAAAAATGGTTTACCTGTATGGTT
GTGTGCTCAATGCTTTGTTAATTATGACACAGAAGATGTTGAACAACGTTTAATTGATGC
ATTGAATCGTAAACTCATGTCTTATACTCTTCAAGATCTTCAATGTACTCGCTGTAAAGA
AATCAAACAAGATAACATCATGCAATATTGTCATTGTGCAGGAAATTACACAAATCTTAT
ACAATCAAGTGAAATTGAAAGTTTAATAACTACTTTTAATCTTGTTGCTGATAATTATTC
GATGATTTTACTAAAAGAATATACTGATACGCTTCTAAATAATATTTAAGCATGAATAAA
TTTGTATAAAATTAAGTTTGTTTAACAAATTGAATA
>g14177.t3 Gene=g14177 Length=245
MNWNICEDLPEEGKCRDKLENFLTLFIEQLADGIESSKALKTLSHHAYDIVTKLYQNFGK
NQEGPATEFIKVLCKILEIDTTVTDELDSLRKNMLRLVGLGEFSDKAVWKEKGKSYILTE
MICQACNHCRDVDLMKDKHRAMKNGLPVWLCAQCFVNYDTEDVEQRLIDALNRKLMSYTL
QDLQCTRCKEIKQDNIMQYCHCAGNYTNLIQSSEIESLITTFNLVADNYSMILLKEYTDT
LLNNI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value |
|---|---|---|---|---|---|---|
| g14177.t3 | PANTHER | PTHR10670 | DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | 1 | 242 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003887 | DNA-directed DNA polymerase activity | MF |
| GO:0003677 | DNA binding | MF |
| GO:0006281 | DNA repair | BP |
| GO:0006260 | DNA replication | BP |
| GO:0008622 | epsilon DNA polymerase complex | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
