General information for g14251.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family D member.
Parent gene
- The parent gene g14251 is located on chr_1: 35856487..35857276 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g14251 | g14251.t1 | isoform | g14251.t1 | 35853403 | 35857276 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon1 | 35853403 | 35854010 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS1 | 35853403 | 35854010 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon2 | 35855328 | 35855551 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS2 | 35855328 | 35855551 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon3 | 35855616 | 35855803 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS3 | 35855616 | 35855803 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon4 | 35855879 | 35855989 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS4 | 35855879 | 35855989 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon5 | 35856061 | 35856406 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS5 | 35856061 | 35856406 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon6 | 35856468 | 35856724 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS6 | 35856468 | 35856724 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon7 | 35856788 | 35857017 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS7 | 35856788 | 35857017 |
| chr_1 | g14251 | g14251.t1 | exon | g14251.t1.exon8 | 35857072 | 35857276 |
| chr_1 | g14251 | g14251.t1 | cds | g14251.t1.CDS8 | 35857072 | 35857276 |
| chr_1 | g14251 | g14251.t1 | TTS | g14251.t1 | 35857466 | 35857466 |
| chr_1 | g14251 | g14251.t1 | TSS | g14251.t1 | NA | NA |
Sequences
>g14251.t1 Gene=g14251 Length=2169
ATGCCTGCAATAGTTTCTAAATTTTTATCAGACGCTGTCGATACATATGAGCGTCGCGGT
AAAAATGTCGAAGTAATTTCAAAGACACTTTTAACCACAGCCGTTCTTGCGTATGTCGTT
AAAATATCATATCCACATATCAAACGTAAAATTAAAGACAAAAAGCCTTCCATTAATGGC
TCGTGTGTAAATTACAACAATAATAATAATACAATCAATAAATATGGAAAGAATTCAAAA
AGTGAAAAGGAAAAGATTGAGGATATCAAAGAAGTTAAAGAGCTCAGTTTATTTGCAAGA
GCATTAAGGCAACCAGGACTGAATTTACAATTTGTGTTACAATTAAGAAAATTAATTGAG
ATTATGATTCCAAGTCTTGTATGCTATGAGACAGGGCTATTAAGTGTTCACACTTTGTGC
CTCATATCGAGAACCTTCTTGAGTATTTATGTTGCTGCAATGGAAGGTGCAATAGTTAAA
TATATTGTGCGAAAAGATGTCAAGAATTTCGTGTATATGTTATTGAAATGGTTTGGAATT
GCAATTCCCGCGACGTTCATAAATTCAATGATTAGATATTTGGAAAACAAATTGGCATTA
GCTTTTAGAACGAGACTTGTCAATCACGCTTATAAGCAATATTTCACAAATCAAACGTAC
TACAAAGTATCAAATTTAGATGGACGCATCGAAAATGCAGATCACCGATTAACAGATGAT
ATTACAACATTCTCTAGTTCAGTAGCACATCTTTATTCTCATTTGACTAAGCCATGTTTT
GACCTTATGCTCATCGGTCTATCTTTAGCACATTCGTCTTATAAAATGAAGGCAAACATA
GTAAATGGACCACTGATAGGATTCTTCGTAATAACAACCACAGCCCACATTATGAGAATT
GCATCGCCAAGATTTGGTCAGTTGGCATGTGAGGAAGCGAATAGAAACGGTTATTTACGT
CATATTCATTCAAGAATCATTACAAATGCAGAGGAAATTGCTTTCTATGGTGGACATAAG
GTTGAACACATACAGCTTAGTGAGGCATATCATCGATTATGTCGGCAAATGAACAGAATT
TTCTCTCAAAAACTGTGGTTTGTCATGCTCGAGCAATTCTTCATGAAATATGTATGGTCC
GGTACAGGCATGATTATGGTATCACTACCAATTTTAACTACAAGCCATTTGAGTAGTGAT
GAAGATCAAAAGAGCAACACAGGAAGTAAAGTTAGTCAACGTACTGAATATTTTACAACT
GCTAGTAACTTACTTAAATCTGGTGCTGATGCTGTTGAGAGACTTATGTCTAGTTATAAA
GAAATTGTAGAACTGGCAGGCTATACAAGTCGTGTTTCAGAAATGTTTCAAGTCTTTGAA
GAAGTATCACAGGGTATTTATAAAAAGACAACAGTTGATGATGAAACAGCTACAGAAGGA
ATACTTGAATTTAAAAATGGTCAACCAGTTGCTAATGGCAAAATATTTTATGATACAGAA
AATATGTCTATAACACTTAAAAATGTTCCAGTTGTGACTCCAAATTGCGATATTGTTGTT
CCAAATTTAACATTAACAATCAGACCTGGCATGCATTTACTTATAACTGGGCCAAATGGC
TGTGGAAAATCGAGTTTATTCCGAATTTTAAGTGGTCTTTGGCCTATTTATAATGGAGAG
CTTCATTTGCCAAAAACATGTGAGGATAAACCATGCATGTTCTACATTCCACAACGACCA
TACATGTCGATTGGAAGTTTGAGAGAGCAAATCATTTATCCTGATTCATTAGATGACATG
ATAGCTAAAAATGTAACAGAAGAAAAGCTAAGGGAAATTTTAAAAATGGTTGCACTTGAG
CACATTGCTATTCGTGACAGTTTTGATGAAGTTCGTGATTGGAAAGATACTTTAAGTGGC
GGTGAAAAACAAAGAATGGCTATTGCAAGATTATTCTATCATAAACCACAATATGCCCTC
CTCGATGAGTGTACCAGTGCTGTTTCTATTGATGTTGAAAGCTCAATTTATGAAACAGCT
AAAAATATGGGTATAACTTTGCTTACGATCACACATCGACCTACTCTTTGGAAATTCCAT
ACCAATATATTGAAATTTGATGGAATGGGAGGATGGATTTTTGAGCCATTGAATGAAAAT
GAACATTAG
>g14251.t1 Gene=g14251 Length=722
MPAIVSKFLSDAVDTYERRGKNVEVISKTLLTTAVLAYVVKISYPHIKRKIKDKKPSING
SCVNYNNNNNTINKYGKNSKSEKEKIEDIKEVKELSLFARALRQPGLNLQFVLQLRKLIE
IMIPSLVCYETGLLSVHTLCLISRTFLSIYVAAMEGAIVKYIVRKDVKNFVYMLLKWFGI
AIPATFINSMIRYLENKLALAFRTRLVNHAYKQYFTNQTYYKVSNLDGRIENADHRLTDD
ITTFSSSVAHLYSHLTKPCFDLMLIGLSLAHSSYKMKANIVNGPLIGFFVITTTAHIMRI
ASPRFGQLACEEANRNGYLRHIHSRIITNAEEIAFYGGHKVEHIQLSEAYHRLCRQMNRI
FSQKLWFVMLEQFFMKYVWSGTGMIMVSLPILTTSHLSSDEDQKSNTGSKVSQRTEYFTT
ASNLLKSGADAVERLMSSYKEIVELAGYTSRVSEMFQVFEEVSQGIYKKTTVDDETATEG
ILEFKNGQPVANGKIFYDTENMSITLKNVPVVTPNCDIVVPNLTLTIRPGMHLLITGPNG
CGKSSLFRILSGLWPIYNGELHLPKTCEDKPCMFYIPQRPYMSIGSLREQIIYPDSLDDM
IAKNVTEEKLREILKMVALEHIAIRDSFDEVRDWKDTLSGGEKQRMAIARLFYHKPQYAL
LDECTSAVSIDVESSIYETAKNMGITLLTITHRPTLWKFHTNILKFDGMGGWIFEPLNEN
EH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g14251.t1 | CDD | cd03223 | ABCD_peroxisomal_ALDP | 504 | 712 | 2.67018E-86 |
| 7 | g14251.t1 | Gene3D | G3DSA:3.40.50.300 | - | 495 | 714 | 4.0E-42 |
| 3 | g14251.t1 | PANTHER | PTHR11384 | ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER | 30 | 721 | 2.2E-272 |
| 4 | g14251.t1 | PANTHER | PTHR11384:SF13 | PEROXISOMAL MEMBRANE PROTEIN RELATED | 30 | 721 | 2.2E-272 |
| 1 | g14251.t1 | Pfam | PF06472 | ABC transporter transmembrane region 2 | 118 | 392 | 1.4E-94 |
| 2 | g14251.t1 | Pfam | PF00005 | ABC transporter | 522 | 666 | 4.0E-21 |
| 12 | g14251.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 24 | - |
| 16 | g14251.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 44 | - |
| 9 | g14251.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 45 | 125 | - |
| 15 | g14251.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 126 | 150 | - |
| 10 | g14251.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 151 | 169 | - |
| 14 | g14251.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 170 | 191 | - |
| 8 | g14251.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 192 | 364 | - |
| 13 | g14251.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 365 | 389 | - |
| 11 | g14251.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 390 | 722 | - |
| 20 | g14251.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 638 | 652 | - |
| 22 | g14251.t1 | ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 138 | 375 | 10.83 |
| 23 | g14251.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 504 | 722 | 13.379 |
| 21 | g14251.t1 | SMART | SM00382 | AAA_5 | 529 | 707 | 1.0E-5 |
| 5 | g14251.t1 | SUPERFAMILY | SSF90123 | ABC transporter transmembrane region | 132 | 384 | 1.11E-10 |
| 6 | g14251.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 497 | 707 | 2.62E-37 |
| 18 | g14251.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 141 | 163 | - |
| 19 | g14251.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 170 | 192 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05676 (ATP-binding cassette, subfamily D (ALD), member 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
