Gene loci information

Transcript annotation

  • This transcript has been annotated as Actin, cytoplasmic A3a.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g14310 g14310.t22 TTS g14310.t22 36559512 36559512
chr_1 g14310 g14310.t22 isoform g14310.t22 36559621 36561070
chr_1 g14310 g14310.t22 exon g14310.t22.exon1 36559621 36560114
chr_1 g14310 g14310.t22 cds g14310.t22.CDS1 36559621 36560114
chr_1 g14310 g14310.t22 exon g14310.t22.exon2 36560433 36560759
chr_1 g14310 g14310.t22 cds g14310.t22.CDS2 36560433 36560751
chr_1 g14310 g14310.t22 exon g14310.t22.exon3 36560993 36561070
chr_1 g14310 g14310.t22 TSS g14310.t22 36561081 36561081

Sequences

>g14310.t22 Gene=g14310 Length=899
TCCATCGTTTTGTGACACTTTAGCTTTGGCAAAAAGTGCTTTGAGTTTTCATCAGAATAA
AAAAAAATATATATTGAAAAATAAAAATGTGTGACGAAGAAGTTGCTGCATTGGTCGTTG
ACAATGGATCAGGAATGTGCAAAGCCGGTTTCGCTGGTGATGATGCACCACGTGCCGTTT
TCCCATCAATTGTCGGTCGTCCACGTCATCAAGGCGTTATGGTCGGTATGGGACAAAAGG
ACTCATATGTTGGTGATGAGGCTCAAAGCAAAAGAGGTATTCTTACCTTGAAATATCCAA
TTGAACACGGTATTGTTACAAACTGGGATGATATGGAAAAGATCTGGCATCATACTTTCT
ACAATGAACTCCGTGTTGCTCCTGAAGAACATCCAGTCTTGCTTATCAAAGAAAAATTGT
GCTATGTTGCACTTGACTTTGAACAAGAAATGGCAACAGCTGCTTCATCAAGCTCATTGG
AGAAATCATATGAATTGCCTGATGGACAAGTCATCACAATCGGAAATGAACGATTCCGTT
GTCCAGAAACTCTCTTCCAACCATCATACATTGGTATGGAATCAAATGGAATTCACGAAA
CAACATACAATTCAATCATGAAGTGTGACGTTGATATCCGTAAAGACTTGTATGCCAACA
CAGTCTTGTCAGGTGGCACAACAATGTTCCCAGGTATCGCTGATCGTATGCAAAAGGAAA
TTACAGCATTAGCTCCATCAACAATGAAGATCAAAATTATTGCACCACCAGAACGTAAAT
ACTCAGTCTGGATCGGAGGTTCAATTTTGGCATCGCTCTCAACCTTCCAACAAATGTGGA
TCAGCAAACAAGAATATGATGAATCAGGCCCATCAATTGTCCACAGAAAATGCTTCTAA

>g14310.t22 Gene=g14310 Length=270
MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQ
SKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLIKEKLCYVALDFEQ
EMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSYIGMESNGIHETTYNSIMKC
DVDIRKDLYANTVLSGGTTMFPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSI
LASLSTFQQMWISKQEYDESGPSIVHRKCF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
17 g14310.t22 Gene3D G3DSA:3.30.420.40 - 9 107 6.3E-46
15 g14310.t22 Gene3D G3DSA:3.90.640.10 Actin; Chain A 108 169 6.5E-80
18 g14310.t22 Gene3D G3DSA:3.30.420.40 - 170 232 6.5E-80
16 g14310.t22 Gene3D G3DSA:3.30.420.40 - 233 266 6.5E-80
3 g14310.t22 PANTHER PTHR11937:SF423 CYTOPLASMATIC ACTIN 1 107 1.9E-171
5 g14310.t22 PANTHER PTHR11937 ACTIN 1 107 1.9E-171
4 g14310.t22 PANTHER PTHR11937:SF423 CYTOPLASMATIC ACTIN 107 269 1.9E-171
6 g14310.t22 PANTHER PTHR11937 ACTIN 107 269 1.9E-171
7 g14310.t22 PRINTS PR00190 Actin signature 27 36 2.5E-23
8 g14310.t22 PRINTS PR00190 Actin signature 50 61 2.5E-23
9 g14310.t22 PRINTS PR00190 Actin signature 62 84 2.5E-23
2 g14310.t22 Pfam PF00022 Actin 4 106 4.3E-34
1 g14310.t22 Pfam PF00022 Actin 107 270 6.0E-66
14 g14310.t22 ProSitePatterns PS00406 Actins signature 1. 54 64 -
13 g14310.t22 ProSitePatterns PS00432 Actins signature 2. 251 259 -
12 g14310.t22 SMART SM00268 actin_3 6 270 2.1E-117
10 g14310.t22 SUPERFAMILY SSF53067 Actin-like ATPase domain 5 108 1.47E-43
11 g14310.t22 SUPERFAMILY SSF53067 Actin-like ATPase domain 104 270 3.79E-72

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

There are no GO annotations for this transcript.

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values