Gene loci information

Transcript annotation

  • This transcript has been annotated as Cystathionine gamma-lyase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g14411 g14411.t8 TSS g14411.t8 358967 358967
chr_4 g14411 g14411.t8 isoform g14411.t8 359199 362631
chr_4 g14411 g14411.t8 exon g14411.t8.exon1 359199 359227
chr_4 g14411 g14411.t8 cds g14411.t8.CDS1 359199 359227
chr_4 g14411 g14411.t8 exon g14411.t8.exon2 361049 361147
chr_4 g14411 g14411.t8 cds g14411.t8.CDS2 361049 361147
chr_4 g14411 g14411.t8 exon g14411.t8.exon3 361370 361434
chr_4 g14411 g14411.t8 cds g14411.t8.CDS3 361370 361434
chr_4 g14411 g14411.t8 exon g14411.t8.exon4 361494 361867
chr_4 g14411 g14411.t8 cds g14411.t8.CDS4 361494 361867
chr_4 g14411 g14411.t8 exon g14411.t8.exon5 361923 362025
chr_4 g14411 g14411.t8 cds g14411.t8.CDS5 361923 362025
chr_4 g14411 g14411.t8 exon g14411.t8.exon6 362289 362631
chr_4 g14411 g14411.t8 cds g14411.t8.CDS6 362289 362347
chr_4 g14411 g14411.t8 TTS g14411.t8 362827 362827

Sequences

>g14411.t8 Gene=g14411 Length=1013
ATGGATCAATTAAATGAGAAATTCTCAGGATTGACGTTTGGAGAACGCTTGGGGTTTAAA
AAAACTGATGACGGATTTGCAACAAAAGCTATACACGCCGGTCAAGAACCAGAACAATGG
AAATGCAGAGCTGTGGTTCCGTTAATTTCTCTTTCAACAACATTCAAACAATTTGCACCA
GCACAACATGCAGGTTATGAATACAGTCGTTCAGGAAATCCAACAAGAAATGTTCTTGAG
ACATGCCTTGCTGCTCTTGATAATGCAAAATTTGCACTTACATTTGCTTCAGGTCTTGGT
GCACAAACTGCCATTATAAGCACTCTTAAAACAGGCGATGCAATTATTACTGGCGATGAT
GTTTATGGAGGAACTAATCGCTTATTTCGTAATCTCGCAGTCAATATGGGAATGGAAGTC
ATTTTTGTTGATATGACTGATCTTAAAAATTTAGAACGTGCTATGAAAGAAAATGTGAAA
CTCGTTTGGTTAGAAACTCCTACAAATCCCAGCATGAAAGTCATTGATATTGAGAATGTT
TGTAAATTTGTTCATGAAAATTCAAAGGCCATTGTTTTAGTTGATAATACATTCCTTTCA
CCATACTTTCAACGTCCAATTGACCTTGGTGCTGATGCTGTAACTTATTCATTAACAAAA
TATATGAATGAGTTGAAAGAGTTATGCATCCAGCACTGCCATCACATCCTCAATATGATA
TTACTTTGAAGCAAACTTATGGTCATTCAGGCATTTTTTCTTTTTATTTACGCAATGGAA
ATCTCGAAAGTTCAACGAAATTCTTGCAAGCTTTGAAAATTTTTATGATAGCAGAATCAC
TTGGTGGATTCGAGAGTTTGGTTGAATTGCCCTCAGTTATGACACATGCAAGCGTTCCCG
AAGAACAAAGAGCTGAACTTGGAATTAATGATGGATTAATTAGAGTAAGTGTCGGATTGG
AAAATGCAAAAGATTTGATTGAAGATTTTGAAAATGCTTTTAAAGTAATTTAA

>g14411.t8 Gene=g14411 Length=242
MDQLNEKFSGLTFGERLGFKKTDDGFATKAIHAGQEPEQWKCRAVVPLISLSTTFKQFAP
AQHAGYEYSRSGNPTRNVLETCLAALDNAKFALTFASGLGAQTAIISTLKTGDAIITGDD
VYGGTNRLFRNLAVNMGMEVIFVDMTDLKNLERAMKENVKLVWLETPTNPSMKVIDIENV
CKFVHENSKAIVLVDNTFLSPYFQRPIDLGADAVTYSLTKYMNELKELCIQHCHHILNMI
LL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g14411.t8 Gene3D G3DSA:3.40.640.10 - 25 235 0
2 g14411.t8 PANTHER PTHR11808:SF15 CYSTATHIONINE GAMMA-LYASE 21 223 0
3 g14411.t8 PANTHER PTHR11808 TRANS-SULFURATION ENZYME FAMILY MEMBER 21 223 0
1 g14411.t8 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 27 223 0
4 g14411.t8 SUPERFAMILY SSF53383 PLP-dependent transferases 24 222 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0019346 transsulfuration BP
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed