General information for g14411.t9
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cystathionine gamma-lyase.
Parent gene
- The parent gene g14411 is located on chr_4: 362015..362631 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14411 | g14411.t9 | isoform | g14411.t9 | 361738 | 362631 |
| chr_4 | g14411 | g14411.t9 | exon | g14411.t9.exon1 | 361738 | 361867 |
| chr_4 | g14411 | g14411.t9 | cds | g14411.t9.CDS1 | 361763 | 361867 |
| chr_4 | g14411 | g14411.t9 | exon | g14411.t9.exon2 | 361923 | 362025 |
| chr_4 | g14411 | g14411.t9 | cds | g14411.t9.CDS2 | 361923 | 362025 |
| chr_4 | g14411 | g14411.t9 | exon | g14411.t9.exon3 | 362081 | 362631 |
| chr_4 | g14411 | g14411.t9 | cds | g14411.t9.CDS3 | 362081 | 362631 |
| chr_4 | g14411 | g14411.t9 | TTS | g14411.t9 | 362827 | 362827 |
| chr_4 | g14411 | g14411.t9 | TSS | g14411.t9 | NA | NA |
Sequences
>g14411.t9 Gene=g14411 Length=784
TGATCTTAAAAATTTAGAACGTGCTATGAAAGAAAATGTGAAACTCGTTTGGTTAGAAAC
TCCTACAAATCCCAGCATGAAAGTCATTGATATTGAGAATGTTTGTAAATTTGTTCATGA
AAATTCAAAGGCCATTGTTTTAGTTGATAATACATTCCTTTCACCATACTTTCAACGTCC
AATTGACCTTGGTGCTGATGCTGTAACTTATTCATTAACAAAATATATGAATGGCCATGC
AGACGTTGTGATGGGGAGTATAGCTACAAGTAATTCAAAACTATATGAAAGTCTCAAATT
TTATCAAAATGCCACTGGAATTGTACCTTCCCCTTTTGACTGTTATTTGGTTAATCGAAG
TCTTAAAACTCTTGCACTTCGTATGGAACACCATTTTAAAACATCAGTAGCTATTGCAAA
ATATCTTGAAACTCATGATAGAGTTGAAAGAGTTATGCATCCAGCACTGCCATCACATCC
TCAATATGATATTACTTTGAAGCAAACTTATGGTCATTCAGGCATTTTTTCTTTTTATTT
ACGCAATGGAAATCTCGAAAGTTCAACGAAATTCTTGCAAGCTTTGAAAATTTTTATGAT
AGCAGAATCACTTGGTGGATTCGAGAGTTTGGTTGAATTGCCCTCAGTTATGACACATGC
AAGCGTTCCCGAAGAACAAAGAGCTGAACTTGGAATTAATGATGGATTAATTAGAGTAAG
TGTCGGATTGGAAAATGCAAAAGATTTGATTGAAGATTTTGAAAATGCTTTTAAAGTAAT
TTAA
>g14411.t9 Gene=g14411 Length=252
MKENVKLVWLETPTNPSMKVIDIENVCKFVHENSKAIVLVDNTFLSPYFQRPIDLGADAV
TYSLTKYMNGHADVVMGSIATSNSKLYESLKFYQNATGIVPSPFDCYLVNRSLKTLALRM
EHHFKTSVAIAKYLETHDRVERVMHPALPSHPQYDITLKQTYGHSGIFSFYLRNGNLESS
TKFLQALKIFMIAESLGGFESLVELPSVMTHASVPEEQRAELGINDGLIRVSVGLENAKD
LIEDFENAFKVI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g14411.t9 | Gene3D | G3DSA:3.40.640.10 | - | 1 | 116 | 0 |
| 5 | g14411.t9 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 117 | 252 | 0 |
| 2 | g14411.t9 | PANTHER | PTHR11808:SF15 | CYSTATHIONINE GAMMA-LYASE | 2 | 251 | 0 |
| 3 | g14411.t9 | PANTHER | PTHR11808 | TRANS-SULFURATION ENZYME FAMILY MEMBER | 2 | 251 | 0 |
| 1 | g14411.t9 | Pfam | PF01053 | Cys/Met metabolism PLP-dependent enzyme | 1 | 250 | 0 |
| 4 | g14411.t9 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 2 | 250 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019346 | transsulfuration | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
