Gene loci information

Transcript annotation

  • This transcript has been annotated as Fatty acid synthase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g14551 g14551.t1 TTS g14551.t1 1321144 1321144
chr_4 g14551 g14551.t1 isoform g14551.t1 1321187 1328241
chr_4 g14551 g14551.t1 exon g14551.t1.exon1 1321187 1322015
chr_4 g14551 g14551.t1 cds g14551.t1.CDS1 1321187 1322015
chr_4 g14551 g14551.t1 exon g14551.t1.exon2 1322176 1322528
chr_4 g14551 g14551.t1 cds g14551.t1.CDS2 1322176 1322528
chr_4 g14551 g14551.t1 exon g14551.t1.exon3 1322584 1323490
chr_4 g14551 g14551.t1 cds g14551.t1.CDS3 1322584 1323490
chr_4 g14551 g14551.t1 exon g14551.t1.exon4 1323597 1325052
chr_4 g14551 g14551.t1 cds g14551.t1.CDS4 1323597 1325052
chr_4 g14551 g14551.t1 exon g14551.t1.exon5 1325158 1325378
chr_4 g14551 g14551.t1 cds g14551.t1.CDS5 1325158 1325378
chr_4 g14551 g14551.t1 exon g14551.t1.exon6 1325546 1327074
chr_4 g14551 g14551.t1 cds g14551.t1.CDS6 1325546 1327074
chr_4 g14551 g14551.t1 exon g14551.t1.exon7 1327206 1327494
chr_4 g14551 g14551.t1 cds g14551.t1.CDS7 1327206 1327494
chr_4 g14551 g14551.t1 exon g14551.t1.exon8 1327595 1328241
chr_4 g14551 g14551.t1 cds g14551.t1.CDS8 1327595 1328241
chr_4 g14551 g14551.t1 TSS g14551.t1 NA NA

Sequences

>g14551.t1 Gene=g14551 Length=6231
ATGACACCAAAACCATTGGAAATTCCAACTAAGAATTTCAAAAATGACAACGAACCAACA
GTCGTCATATCAGGCATGTCCGGAAGATTTCCAAAGTCGCAAAATATCGCAGAATTTAAA
GAAAACTTGATGAATAAAGTTGACATGACCGAACCATGTGAAACACGTTTTAAACAACTT
AATGAGCTCATTCCTGACCGTTGTGGTCAAACTAAAAATATTGAAAAATTCGATTCAGCT
TTCTTCAACATTCCAGCTGAATTTGCAAATCATTTGGATCCAATGTGTCGAACATTACTT
GAACATGTTTATGAAGCAATTATTGATGCTGGTGTATCACCAAAAAGTATCAGAGGAACT
AAAACTGGTGTCTTTGTTGGCTGCTGTTTTGCTGATTGTCATGAATATTCGATTAGAGAA
AAGAGTGGCAAAGAAGTTACAGGATCATTGAGAACTTTAATTCCAAACCATGTGTCTTAT
GCATTTGATTTCAAAGGGCCCTCTTATGTAATTGATTCAGCTTGTAGTAGTAGTGGATAT
GCTGCTGATGTTGCATTGAAATCAATCAAAAGTGGTGAATGTGATGCAGCTATTTTAGCT
GGAACTAATTTAGTGCTCGGACCAGCATTGAGCATGGGATTTAATAAAATGGGAGTGTTA
TCAAAAGACGGTATAGGAAAATCATTCGATGAAGAAGCCAATGGCTATTGTCGTGCTGAT
GCAATTGTTGCTCTATTTTTACAAAAATCAACTGATGCTAAACGAGTTTATGCAACTTTT
GTCCATGCTAAGAAAAATGTTGATGGTTATAAAAAGGAAGGGTTGCCATTTCCATCAAAA
GTTATGCAAGTGAAACTTTTTGAAGAATTTTATCAAGAAATTGGGATGAATCCAAATGAT
GTTGATTATATTGAAGCTCATAGCACTGGAACTAAAGTTGGTGATTTAGAAGAAGTTCCA
GGCCTTGATTCAATCTTCTGTTCAAATCGGAAATCTCCTTTACTAATTGGTTCATTAAAG
TCTAACATGGGACATTCTGAAGCTGCATCAACAACAAGTTCGATTGTGAAATCGCTTCTA
ATTTTTGAAAATAAAAAACTTTTTTCGAATTTGCACTTTAATAAACCAAGATCAGGCATT
GAAGCATTTGAAAAAGGAAGCATTAAAGTGGTAGATGAAATGACAGATTTCAAAGGTTCT
CTAATTGGTATCAATTCTTTTGGTGTTGGTGGTGCAAATGTGCATTTGCTTTTGAAATCA
CATGAGAAAGAGAAAATCAACAATGGCGCAATCAATGATAAACTAGAAAGAATTTTACTT
TGGTCAGGTCGAACAAAGGAAGCTGTAGAAATGATATTTGATAGCGTAACTAAAGCACCA
TTGGATGCTGAACATATTGCATTATTACAGCATTCACAAGAGCAAACAATTGCACTGAAT
ACTTTTCGTGGTTTTGCAATTTTTGATCCACGAATTTCAGTCGATGAAAATTCAAAATGT
GTACATAAAGAAATCAACAATTATCTTGATGGTAAACGAAAAATCGCATTCGTGTATAGT
GGCATAGGCTCACAATGGCCACAAATGATTTCTGACTTGATGAGAATTCCAACATTTGCA
AAATCAATCAATAAATGTCATGAAATTTTATTATCAAAAAATCTCAATTTGAAGGAAATT
TTATCATCACCAAATGAAGCTGCAAATGTGCTTCATTCATACATTTCTATTGCTGCAATA
CAAATAGCATTGACAGACATTTTGACAACTATTGGTGTGAAAGCTGATTATATTTTGGGA
CATTCAGTAGGTGAATTGGGTTGTGCTTATGCTGATAATTGTTTAACTGATGAAGAAATG
ATTTTATGTGCATATTCACGTGGTATTGCGACACTTGAAACTAAAACAATTAATGGTGCA
ATGGCTGCTGTTGGTGTTGGTTATAATGAACTTAAAGGTCGACTTATTGAAGGTGTTGAA
ATTGCTTGTCATAATAATTCAACTTCATGCACAATTTCTGGGCCTCGTGTGAAAATTGAA
AAATTCATCCAGCAACTTAAGGCAGAAAATTGCTTTGTTCGTGAAGTTAATTCGGGTGGA
ATTGCTTTTCATAGCAGTTACATTGCACCAATGGGACCAAAATTACAAAAACTTCTTGAA
AGTGTCATAAAAAATCCAAAAGAAAGATCACAAAAATGGATCAGCACAAGTGTACCAAAG
GAAAAGTTCGAAAATGAAGAATCACGTTTGTCATCAGCTAAATATCATACAAACAATTTA
TTAAATCCAGTTTTATTTGAAGAAGCTCTCGCTAGTTTACCTGAAAAATGTTTGACAATT
GAAATTGCTCCATGTGGATTATTGCAAGCAATTTTAAAACGAGCTGTGCCTAATGGACTT
CATTTTAGTTTGACAAAGCGAGAACATAAGGAAAATGCAAGATTTTTGATGAATTCACTT
GGAAAAATTTTCACCAATGGTGTTGACATGAGCATTCAAAATCTTTACCCAAAAATCAAT
TTTCCTGTTTCACGTGGAACTTCAATGATTTCACCATTGATTAAATGGGACCACAGCAGT
AATTTCAAAGCTTTTAAAATGGATGAACTTGATGTCAATGAATTAAAAGTTCCAATTATG
ATGAGAGATCCAAATTTTGAATTTTTAGCTGGTCATAAAATTGAAGGAAAAATAATTTTC
CCTGGCACTGGTTATCTTTACATTGCTTGTCGTCTTGCTGCAGCTCATCATAAGCAAAAA
TTTGAAGATTTCGATATTGAAATGGATGACATTCGATTCCATAATGCTTGTTTCTTATCA
TATGAAAAAGATGTTGAACTTATGGCAGTTTATCATGGTGGTGATGGAAAATTTGAAATT
CGTGAAGGCAAAACTGTCATGTGTACTGGTTATATTCGTCCTAGTTCTAGTTCTAAGATA
AGAAATTATGAAGTTAAAGACAATAGTCACATTCCAGAAATGAATGGTGATGAATTTTAC
AAAGAACTTCGAATTCGAAATTACAATTATGAAAAATTATTTAGAAATGTTGTTGGTGCA
AAAATTGATGGCAGTCAAGTGAGAGCAAAATGGGAAAATAATTGGATTGCATTTTTTGAT
AATCTCGGGCAATTAGTATTAATTTCAAAAGACGCGCGTGGATCATTAGTTCCAATTCGT
ATAAGAAAAGTTGTTTTAAGTCCAAGAGCATTTTTAGAACAATTGAAAACATTTGAAAAT
TTATCAGATCATGAAAAAATTGCAACAGCTTTTTACGATAAAGATTTAGACATGGTTCAT
TGTCCTGGAATGGAATTTCGTGGATTTACTTTTACATCTATTCCTAAATTACTCTATCGT
GGTCATCATGTTATGAGCTGTTATAAATTTATTTCACATTTTCCAACACCTGTCATAACT
GCTGAAAATGCTGCAAAAATTTGTGTCCAATTGGCAATGGAAAATTCAATGATTTTGAAA
ATTTCTTCTATTGAAATCGATGAAAGTGAAGAGTTAGAAGAGAATTCAGGAATTTTCAAT
GAATTTATGGCTAAAGCTATTGAATCTGTGCCTATTGTGACTTCTGATTTGATTTTTTTA
AGTAACAGAAATATTGAAAACGCAAATTTTGTGACAATTGAAAAATTGGAAACTTTAAAG
ACTAAAAAATCTGCTGATTTTCTGATTCGAAAAGGTTTTGAAAATCTTGAGACAATTGAG
CAACATTTGGCTGAATCTGCCTTTGTCATTTGTCGCAATTCAATTTCAGCAAATTCACCT
AAAAATTTACCCAAGAATTTTTCACTCACTGCAATTTTAAATCTTGAAAATGAAAAAATC
TTTTTAATTCAATATCACAAAAATCTACAAGAAATTCCAACAAATGTCATCAAAATATCA
AGCAGAGATTTTCAATGGTTGGAGCAACTTAAAGAAAGCATAAAAGAAAAACCAACTATT
GTTTATGCACAAAACGAAAAAAATTCTGGAATTCTTGGACTTGTAAATTGTTTAAGAAGA
GAACCGAATTGTGGAAATTTACGATGTGTTTTTATTGATGATGATTCTGCTCCTGATTTT
GAAATTGAAAAAGAATTTTATAAGAAGCAGTTGGAAAAAGGACTTGCTGTTAATATTTAT
AGAAATGGTCAATGGGGTTCTTATCGTCACTTAACTCTTCAACAACCTTCAATGTCAAAG
ATTTCTCCAACAGAAGTCTCAGCATTTTTAAATATTCAAACTCGTGGAGATCTTTCATCA
CTTAAATGGATTCAACAGCCTTTAAAACTAAAAGTTGATGGAAAACATGAAGTTGTTCGT
ATTCATTATGCAGCATTAAATTTTCGTGATGTCATGATTGCAACTGGTCGTGTTGGTCCA
GAAATGTTTGGTGATAAAAGAAATGATCAATTGAAAATTCTTGGATTTGAATTTTCTGGT
ATAACAATAACAGGTCGAAGAGTTTATGGTATGGCACCATATGGATGTCTTTCAACACAT
TTTTCTGATGAAAGAGTCATTTTACTTGATGTACCAAAAGAATGGTCACTAGAACAAGCA
GCAACAATTATTGGAACTTATGGAACAATAGCAATATCACTTTTTATGAAATGTCAAATT
GAAAAAGATAAATCAATTTTAATTCATGCTGGCTCGGGTGGTGTTGGTTTATCAGCTTTA
TATGTTGCTTTTGCAAGTGGCATGGAGGTTTTTACAACTGTCAGTAATGAAGAAAAACGA
CAGTTTTTGTTGGACACTTTTCCAAAATTAAAACCTGAAAATATTGGAAATTCACGTGAT
ACAACCTTTGAAGATATGATTATGAAAAGAACAAATGGAAGAGGTGTTGATTATGTCCTA
AATTCTCTATCTGATGATAAACTTTTGGCTTCACTTAGATGTGTTGCTAAAGCTGGATAT
TTTATTGAAATTGGCAAATCTGACATTGTTAGAGACAATAAAATTAATTTGGCTTGCTTT
GCGAATGAATTGACATTTATTTCTGTCAATATGGTCAATTGTGCTTTTACCGAAGGTCGT
TCTTTTGAGGATTTAAAATCATTCGTCAAACAAGGAATCAAGAAAAAATTCATTGTTCCA
TTGAAAACGACAGTTTTCAAGCCAGAACAAACTGAAGAAGCTTTCAGATATTTAGCAAGT
GGTAAACATATTGGAAAAGTTCTTATTCAACTTAGAGAAGGTGAAAAGCTGACTAAAGAA
CTTCTTCCAATGGAAATAATTCCAGCAATGTGCTTCAATGAAAATCACAGTTATATAATT
GTTGGTGGTCTTGGTGGATTTGGTTTGGAACTTGCAGATTGGATGATTTTAAGAGGCGGA
AAGAAAATTGTGCTGAGCTCAAGTCGTGGAATTTCTAATAATTATCAAACCTATAGAATG
AGACTCTGGGAAACTTACAATGCACAAATAAAAATTTCAACAGCTGATGTCACCACTGCA
GCAGGTTGTCAACAGTTAATCAATGAAGCATCAAAACTTGGTCCAATTGGTGGGATTTTT
AATTTAGCAGTAAAATTGAACGATGCATTATTTGAAAATCAAACACAAACAACATTTGAG
CAAACACTTGCAACTAAAGCAATCGCAACAAAACATCTTGATAAAATTTCAAGAAATTTC
TGTCCAAGTCTTGAATTTTTTGTTGTTTTTTCGAGTGTCTCATGTGGATTAGGTAATGCA
GGACAAAGTAATTATGGCATGGCAAATTCAATTATGGAAAGAATAATTGAGCAACGACAT
CAAGATGGCTTGCCAGCCAAAGCAATTCAATGGGGAGCAATAGGTGATGTTGGAATTTTA
GCAGATTTAAATGAAGAAAAAGAAATTAGTGGAACACTTATGCAAAGAATTTCATCATGT
CTTGAATCTATGGACACTTTAGTTCAATCATCAGATCCAATTGTTTGTAGCATGGTAGTA
GCTGAGAAGGGAAAAGCTATCTCAAGTAAAGCAGCAATGATTGAAAATATTTTGAAACTT
CTTGGTATTAAAGACATTAGTGCATATCCAGCTGATACGAAAGTTAGTGATTTTGGTATG
GACTCATTGCTTTCAGTCGAATTTATGCAACTTTTTGAGCGTGAATTTAACGTGCAATTG
TCAGTTGATGAAATGAGATCAATGACATTAGAAAAATTAATGAGTTATAGCAATGGAAAA
ATTGATGGAAAGAAAATGAAAATTGTTGATGGAAAAGTTGTTGAAATTTAA

>g14551.t1 Gene=g14551 Length=2076
MTPKPLEIPTKNFKNDNEPTVVISGMSGRFPKSQNIAEFKENLMNKVDMTEPCETRFKQL
NELIPDRCGQTKNIEKFDSAFFNIPAEFANHLDPMCRTLLEHVYEAIIDAGVSPKSIRGT
KTGVFVGCCFADCHEYSIREKSGKEVTGSLRTLIPNHVSYAFDFKGPSYVIDSACSSSGY
AADVALKSIKSGECDAAILAGTNLVLGPALSMGFNKMGVLSKDGIGKSFDEEANGYCRAD
AIVALFLQKSTDAKRVYATFVHAKKNVDGYKKEGLPFPSKVMQVKLFEEFYQEIGMNPND
VDYIEAHSTGTKVGDLEEVPGLDSIFCSNRKSPLLIGSLKSNMGHSEAASTTSSIVKSLL
IFENKKLFSNLHFNKPRSGIEAFEKGSIKVVDEMTDFKGSLIGINSFGVGGANVHLLLKS
HEKEKINNGAINDKLERILLWSGRTKEAVEMIFDSVTKAPLDAEHIALLQHSQEQTIALN
TFRGFAIFDPRISVDENSKCVHKEINNYLDGKRKIAFVYSGIGSQWPQMISDLMRIPTFA
KSINKCHEILLSKNLNLKEILSSPNEAANVLHSYISIAAIQIALTDILTTIGVKADYILG
HSVGELGCAYADNCLTDEEMILCAYSRGIATLETKTINGAMAAVGVGYNELKGRLIEGVE
IACHNNSTSCTISGPRVKIEKFIQQLKAENCFVREVNSGGIAFHSSYIAPMGPKLQKLLE
SVIKNPKERSQKWISTSVPKEKFENEESRLSSAKYHTNNLLNPVLFEEALASLPEKCLTI
EIAPCGLLQAILKRAVPNGLHFSLTKREHKENARFLMNSLGKIFTNGVDMSIQNLYPKIN
FPVSRGTSMISPLIKWDHSSNFKAFKMDELDVNELKVPIMMRDPNFEFLAGHKIEGKIIF
PGTGYLYIACRLAAAHHKQKFEDFDIEMDDIRFHNACFLSYEKDVELMAVYHGGDGKFEI
REGKTVMCTGYIRPSSSSKIRNYEVKDNSHIPEMNGDEFYKELRIRNYNYEKLFRNVVGA
KIDGSQVRAKWENNWIAFFDNLGQLVLISKDARGSLVPIRIRKVVLSPRAFLEQLKTFEN
LSDHEKIATAFYDKDLDMVHCPGMEFRGFTFTSIPKLLYRGHHVMSCYKFISHFPTPVIT
AENAAKICVQLAMENSMILKISSIEIDESEELEENSGIFNEFMAKAIESVPIVTSDLIFL
SNRNIENANFVTIEKLETLKTKKSADFLIRKGFENLETIEQHLAESAFVICRNSISANSP
KNLPKNFSLTAILNLENEKIFLIQYHKNLQEIPTNVIKISSRDFQWLEQLKESIKEKPTI
VYAQNEKNSGILGLVNCLRREPNCGNLRCVFIDDDSAPDFEIEKEFYKKQLEKGLAVNIY
RNGQWGSYRHLTLQQPSMSKISPTEVSAFLNIQTRGDLSSLKWIQQPLKLKVDGKHEVVR
IHYAALNFRDVMIATGRVGPEMFGDKRNDQLKILGFEFSGITITGRRVYGMAPYGCLSTH
FSDERVILLDVPKEWSLEQAATIIGTYGTIAISLFMKCQIEKDKSILIHAGSGGVGLSAL
YVAFASGMEVFTTVSNEEKRQFLLDTFPKLKPENIGNSRDTTFEDMIMKRTNGRGVDYVL
NSLSDDKLLASLRCVAKAGYFIEIGKSDIVRDNKINLACFANELTFISVNMVNCAFTEGR
SFEDLKSFVKQGIKKKFIVPLKTTVFKPEQTEEAFRYLASGKHIGKVLIQLREGEKLTKE
LLPMEIIPAMCFNENHSYIIVGGLGGFGLELADWMILRGGKKIVLSSSRGISNNYQTYRM
RLWETYNAQIKISTADVTTAAGCQQLINEASKLGPIGGIFNLAVKLNDALFENQTQTTFE
QTLATKAIATKHLDKISRNFCPSLEFFVVFSSVSCGLGNAGQSNYGMANSIMERIIEQRH
QDGLPAKAIQWGAIGDVGILADLNEEKEISGTLMQRISSCLESMDTLVQSSDPIVCSMVV
AEKGKAISSKAAMIENILKLLGIKDISAYPADTKVSDFGMDSLLSVEFMQLFEREFNVQL
SVDEMRSMTLEKLMSYSNGKIDGKKMKIVDGKVVEI

Protein features from InterProScan

Transcript Database ID Name Start End E.value
30 g14551.t1 CDD cd00833 PKS 21 418 0.0e+00
31 g14551.t1 CDD cd05195 enoyl_red 1436 1729 0.0e+00
29 g14551.t1 CDD cd08954 KR_1_FAS_SDR_x 1753 1981 0.0e+00
25 g14551.t1 Gene3D G3DSA:3.40.47.10 - 19 420 0.0e+00
23 g14551.t1 Gene3D G3DSA:3.30.70.3290 - 435 863 0.0e+00
28 g14551.t1 Gene3D G3DSA:3.40.366.10 - 511 827 0.0e+00
24 g14551.t1 Gene3D G3DSA:3.10.129.110 - 874 1117 0.0e+00
22 g14551.t1 Gene3D G3DSA:3.40.50.720 - 1302 1980 0.0e+00
27 g14551.t1 Gene3D G3DSA:3.90.180.10 - 1395 1750 0.0e+00
26 g14551.t1 Gene3D G3DSA:1.10.1200.10 - 1985 2068 0.0e+00
9 g14551.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 16 2060 0.0e+00
10 g14551.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 16 2060 0.0e+00
4 g14551.t1 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 20 253 0.0e+00
1 g14551.t1 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 373 0.0e+00
8 g14551.t1 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 376 487 0.0e+00
6 g14551.t1 Pfam PF00698 Acyl transferase domain 517 828 0.0e+00
3 g14551.t1 Pfam PF14765 Polyketide synthase dehydratase 885 1068 0.0e+00
7 g14551.t1 Pfam PF13602 Zinc-binding dehydrogenase 1597 1729 0.0e+00
2 g14551.t1 Pfam PF08659 KR domain 1757 1935 0.0e+00
5 g14551.t1 Pfam PF00550 Phosphopantetheine attachment site 1997 2053 1.1e-06
20 g14551.t1 SMART SM00825 Beta-ketoacyl synthase 21 423 0.0e+00
19 g14551.t1 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 518 809 0.0e+00
18 g14551.t1 SMART SM00829 PKS_ER_names_mod 1416 1729 0.0e+00
21 g14551.t1 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1756 1937 0.0e+00
12 g14551.t1 SUPERFAMILY SSF53901 Thiolase-like 15 419 0.0e+00
11 g14551.t1 SUPERFAMILY SSF52151 FabD/lysophospholipase-like 514 799 0.0e+00
17 g14551.t1 SUPERFAMILY SSF55048 Probable ACP-binding domain of malonyl-CoA ACP transacylase 638 694 6.0e-07
15 g14551.t1 SUPERFAMILY SSF50129 GroES-like 1422 1549 0.0e+00
13 g14551.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1518 1677 0.0e+00
14 g14551.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1754 1956 0.0e+00
16 g14551.t1 SUPERFAMILY SSF47336 ACP-like 1993 2056 0.0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF
GO:0016740 transferase activity MF
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values