General information for g14563.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cystathionine gamma-lyase.
Parent gene
- The parent gene g14563 is located on chr_4: 1358788..1361186 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14563 | g14563.t1 | TTS | g14563.t1 | 1358679 | 1358679 |
| chr_4 | g14563 | g14563.t1 | isoform | g14563.t1 | 1358788 | 1361186 |
| chr_4 | g14563 | g14563.t1 | exon | g14563.t1.exon1 | 1358788 | 1359199 |
| chr_4 | g14563 | g14563.t1 | cds | g14563.t1.CDS1 | 1358788 | 1359199 |
| chr_4 | g14563 | g14563.t1 | exon | g14563.t1.exon2 | 1359305 | 1359958 |
| chr_4 | g14563 | g14563.t1 | cds | g14563.t1.CDS2 | 1359305 | 1359958 |
| chr_4 | g14563 | g14563.t1 | exon | g14563.t1.exon3 | 1360034 | 1360132 |
| chr_4 | g14563 | g14563.t1 | cds | g14563.t1.CDS3 | 1360034 | 1360132 |
| chr_4 | g14563 | g14563.t1 | exon | g14563.t1.exon4 | 1361152 | 1361186 |
| chr_4 | g14563 | g14563.t1 | cds | g14563.t1.CDS4 | 1361152 | 1361186 |
| chr_4 | g14563 | g14563.t1 | TSS | g14563.t1 | 1361294 | 1361294 |
Sequences
>g14563.t1 Gene=g14563 Length=1200
ATGAATGCAGCTGACATAATTGCAGAATATACAGAACCACCATTTGCTGAAAAGTTAGGA
TTTCTTAAAAATCCATCAAGTTTTGCTACAAAAGCAATTCATACGGGTGAAAATTCTAAT
CAACTTGAATGCAGTTCAATAATTCCTCTAATAAACCTCACATCAACTTACAAACTTGAA
GAAGCTCACAATCCTTATGGGTATCAATATAGTCGTTTTGGAAATCCAACAAGAAATGGT
CTCGAAACATGTTTGGCAGCATTAGAAAATTCGAAATTCGCCATCACTTTTTCATCACGC
TTAGGTGCACAAACTGCAGTAATTTCATCACTTAAGCGTGGCGAAGGAATTTTAGTCGAT
TGCGATGCAAATTCAAGTTGCATGAAATTGTTTAAAAATTTTGCCAAAAGCATGGAAATG
AATGTGAAATTCGTGGATTTTAATAATTTTGAAGAATTTAAAAATTTTTTAAATGAAAAT
ATAAAATTAATTTGGTTTGAAACTCCATCAAGTGAAACAATGAAAATTATTGACATTAAA
AAAATTTCATCATTTGTAAAGGAAAATTTTTCAAATGCAAAAATTGTTGTGGACAATACA
ATTTTGACGAGTTATTTACAAAGGCCTTTGGAATTTGGTGCTGATATTGTTATTTATTCA
ATTACGAAATATTTGCATGGACACTCTGATGTTACGATGGGATCACTTGCAATAAATGAT
GAAAAAATTCATGAAAAACTTAAGTATCATCAAGGTGCAATGGGTGTTATACCTAGTCCA
TTTGATTGTTTTATGGTCAACAGAAGTCTCAAAACTCTCGCACTTCGCATGGATCTTCAT
ATGAAAAATTCATTTATTGTAGCAAAATATCTTGAAAATCAATCAGAAGTTGAAAAAGTT
TTTCATCCAGCTCTCAAATCTCATCCACAATATGAAATTGCAATAAAACAATCGTATGGT
CATTCGGGTGTTTTCACATTTAAATTGAAAAATAATGAAAAAATTGAAAAGTTTTTAAAA
GCATTAAAAATTTTTCTACAAATTGAAAGTCCTTGTGGAAGTTCAATGAAATGTTTGATA
AGTGATGAAAATGAAGAAAAATGTGAATTGAAAGGATTAATTAGTGTATCAATTGGATTG
GAAAATATTGAAGATTTAATTGGTGATATTAAAAATGCTTTAATTGAAATGAAAAATTAA
>g14563.t1 Gene=g14563 Length=399
MNAADIIAEYTEPPFAEKLGFLKNPSSFATKAIHTGENSNQLECSSIIPLINLTSTYKLE
EAHNPYGYQYSRFGNPTRNGLETCLAALENSKFAITFSSRLGAQTAVISSLKRGEGILVD
CDANSSCMKLFKNFAKSMEMNVKFVDFNNFEEFKNFLNENIKLIWFETPSSETMKIIDIK
KISSFVKENFSNAKIVVDNTILTSYLQRPLEFGADIVIYSITKYLHGHSDVTMGSLAIND
EKIHEKLKYHQGAMGVIPSPFDCFMVNRSLKTLALRMDLHMKNSFIVAKYLENQSEVEKV
FHPALKSHPQYEIAIKQSYGHSGVFTFKLKNNEKIEKFLKALKIFLQIESPCGSSMKCLI
SDENEEKCELKGLISVSIGLENIEDLIGDIKNALIEMKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g14563.t1 | Coils | Coil | Coil | 380 | 399 | - |
| 6 | g14563.t1 | Gene3D | G3DSA:3.40.640.10 | - | 26 | 272 | 1.5E-68 |
| 5 | g14563.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 273 | 396 | 6.0E-27 |
| 2 | g14563.t1 | PANTHER | PTHR11808 | TRANS-SULFURATION ENZYME FAMILY MEMBER | 24 | 397 | 6.9E-100 |
| 8 | g14563.t1 | PIRSF | PIRSF001434 | CGS | 18 | 398 | 1.1E-100 |
| 1 | g14563.t1 | Pfam | PF01053 | Cys/Met metabolism PLP-dependent enzyme | 29 | 394 | 6.6E-102 |
| 4 | g14563.t1 | ProSitePatterns | PS00868 | Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. | 215 | 229 | - |
| 3 | g14563.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 50 | 394 | 4.67E-78 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019346 | transsulfuration | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed