General information for g1457.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inorganic pyrophosphatase.
Parent gene
- The parent gene g1457 is located on chr_3: 11047462..11047850 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1457 | g1457.t1 | TSS | g1457.t1 | 11046179 | 11046179 |
| chr_3 | g1457 | g1457.t1 | isoform | g1457.t1 | 11046205 | 11047585 |
| chr_3 | g1457 | g1457.t1 | exon | g1457.t1.exon1 | 11046205 | 11046271 |
| chr_3 | g1457 | g1457.t1 | cds | g1457.t1.CDS1 | 11046205 | 11046271 |
| chr_3 | g1457 | g1457.t1 | exon | g1457.t1.exon2 | 11046555 | 11046673 |
| chr_3 | g1457 | g1457.t1 | cds | g1457.t1.CDS2 | 11046555 | 11046673 |
| chr_3 | g1457 | g1457.t1 | exon | g1457.t1.exon3 | 11046751 | 11047298 |
| chr_3 | g1457 | g1457.t1 | cds | g1457.t1.CDS3 | 11046751 | 11047298 |
| chr_3 | g1457 | g1457.t1 | exon | g1457.t1.exon4 | 11047444 | 11047585 |
| chr_3 | g1457 | g1457.t1 | cds | g1457.t1.CDS4 | 11047444 | 11047585 |
| chr_3 | g1457 | g1457.t1 | TTS | g1457.t1 | 11047864 | 11047864 |
Sequences
>g1457.t1 Gene=g1457 Length=876
ATGGCTGGAAAATTTGTTGCTGTCGAAAAAGGAGCTCCCAATTCAAAGGATTTCCGAGTA
TTCTTTAAAAATGCAGCTGGAACACCAATTTCACCTTTACATGACATTCCTTTATTTGCC
AACGATAGTTCACAGGTCTATAATATGGTAGTTGAAGTGCCGCGTTGGACAAATGCAAAG
ATGGAGATTACACTCGCGGAAGAATTAAATCCAATCAAACAAGATATTAAAAAAGAGAAG
CTTAGATTTGTTGCTAATGTATTCCCTCATAAAGGATACATTTGGAATTATGGTGCATTG
CCTCAAACATGGGAATATCCTGGACATGTAGATAAATCAACTGGTTGCAAAGGTGACAAC
GATCCAATTGATGTTTGTGAAATTGGCTCACGTGTAGCTAAACGCGGTGATGTCATTCAA
GTTAAAATTCTCGGCACTCTTGCACTCATCGATGAAGGTGAAACTGACTGGAAAGTTTTT
GCTATTGATATTAATGATCCAGTTGCTGATCAAATGGAAGATGTACAAGACATTGAGAAA
TTCTTCCCTGGTTTATTAAGAGCAACAGTAGAATGGTTCAAATTTTATAAAGTACCAGAT
GGTAAACCTGAAAATCAATTTGCATTTAATGCTGAAGCAAAGAACGCTGCATTTGCTAAA
AATATCGTGACGGAAACTCACGCTTTTTGGCAGCGCTTGATTAAAAAAGAAGTCGAAAGC
CCTAAGATTTCATGTTCAACTGTAGAAAATACAGATTCACCATTTGTTATCTCTAGCGAT
CAAGCAGAAGAAATATTTTCAAAAGCCACTGAAGGAGGCGATCCAGAGCCATTTAATGAA
GCAATCAACAAGTGGCATTTTCTTCATCTTCAATAG
>g1457.t1 Gene=g1457 Length=291
MAGKFVAVEKGAPNSKDFRVFFKNAAGTPISPLHDIPLFANDSSQVYNMVVEVPRWTNAK
MEITLAEELNPIKQDIKKEKLRFVANVFPHKGYIWNYGALPQTWEYPGHVDKSTGCKGDN
DPIDVCEIGSRVAKRGDVIQVKILGTLALIDEGETDWKVFAIDINDPVADQMEDVQDIEK
FFPGLLRATVEWFKFYKVPDGKPENQFAFNAEAKNAAFAKNIVTETHAFWQRLIKKEVES
PKISCSTVENTDSPFVISSDQAEEIFSKATEGGDPEPFNEAINKWHFLHLQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g1457.t1 | CDD | cd00412 | pyrophosphatase | 45 | 227 | 1.92931E-67 |
| 6 | g1457.t1 | Gene3D | G3DSA:3.90.80.10 | Inorganic Pyrophosphatase | 6 | 291 | 4.0E-127 |
| 2 | g1457.t1 | PANTHER | PTHR10286:SF49 | INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL | 5 | 262 | 3.4E-119 |
| 3 | g1457.t1 | PANTHER | PTHR10286 | INORGANIC PYROPHOSPHATASE | 5 | 262 | 3.4E-119 |
| 1 | g1457.t1 | Pfam | PF00719 | Inorganic pyrophosphatase | 49 | 231 | 2.7E-54 |
| 5 | g1457.t1 | ProSitePatterns | PS00387 | Inorganic pyrophosphatase signature. | 119 | 125 | - |
| 4 | g1457.t1 | SUPERFAMILY | SSF50324 | Inorganic pyrophosphatase | 6 | 288 | 4.19E-102 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000287 | magnesium ion binding | MF |
| GO:0004427 | inorganic diphosphatase activity | MF |
| GO:0006796 | phosphate-containing compound metabolic process | BP |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K01507 (inorganic pyrophosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
