General information for g14845.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Molybdenum cofactor synthesis protein cinnamon.
Parent gene
- The parent gene g14845 is located on chr_4: 2647484..2648172 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g14845 | g14845.t1 | TSS | g14845.t1 | 2645756 | 2645756 |
| chr_4 | g14845 | g14845.t1 | isoform | g14845.t1 | 2645856 | 2648172 |
| chr_4 | g14845 | g14845.t1 | exon | g14845.t1.exon1 | 2645856 | 2645886 |
| chr_4 | g14845 | g14845.t1 | cds | g14845.t1.CDS1 | 2645856 | 2645886 |
| chr_4 | g14845 | g14845.t1 | exon | g14845.t1.exon2 | 2645937 | 2646122 |
| chr_4 | g14845 | g14845.t1 | cds | g14845.t1.CDS2 | 2645937 | 2646122 |
| chr_4 | g14845 | g14845.t1 | exon | g14845.t1.exon3 | 2646178 | 2646310 |
| chr_4 | g14845 | g14845.t1 | cds | g14845.t1.CDS3 | 2646178 | 2646310 |
| chr_4 | g14845 | g14845.t1 | exon | g14845.t1.exon4 | 2646405 | 2646625 |
| chr_4 | g14845 | g14845.t1 | cds | g14845.t1.CDS4 | 2646405 | 2646625 |
| chr_4 | g14845 | g14845.t1 | exon | g14845.t1.exon5 | 2646686 | 2648172 |
| chr_4 | g14845 | g14845.t1 | cds | g14845.t1.CDS5 | 2646686 | 2648172 |
| chr_4 | g14845 | g14845.t1 | TTS | g14845.t1 | 2648291 | 2648291 |
Sequences
>g14845.t1 Gene=g14845 Length=2058
ATGGTAGATTTTACATATGGAATCATAACAATTTCCGATCGGTGTTTTCGTGGTGAGACA
AAAGATGAAAGCGGACCAAAAATCAAGTATCTTTTACAAGATGAATATAATGCCCATAAC
ATCAAACAAGAAATCATTCCAGACGATCAAAATAAAATTGAAGAAATTTTAATCCTTTAT
TCTGATGTTTTAAAAATTAATTGTATTTTTACAACAGGTGGAACTGGGTGTTCTCCTAGA
GATGTCACACCAGAAGCAACGAGAAAAATTATTCATAAAGAATTTCCGCAACTTTCAATG
GTTATGCTTTTAGAAGGTTTAAGAAAGACTGAATTTGCTGCACTTACGAGACTGATCTGT
GGAATTCGCAACAATTCACTCATTATAAATTTCCCAGGCAGTGTCAAAGCAGTAACTGAA
AGTTTCAATGCTATTAAACGCCTGATTCCACATGCAGTTGACTTAATTTGTGACATAAAA
GATAAAACTGAATCTGTTCATAAGCAAATTCAATCGGGAACTTCCAAAAATGCTACAAAT
GATTTTTATAGAGAAATTAAAGAAAAAACAAATGATTCGATTGATGAGGTGTTGAAAAAT
TATAAACAAAATTCTGCTTCAAACTCTGAATCAAATTTAAAAAGAAGAAATGAAGATACA
GAAGTTGAACCTAAGAAAATTGACAATCAAAAATCAAATCAGAGCTCTACAAAGCCTCAG
ACTGAAAGTTCTGCAGCAAAAGAAGTTCCTAAACCTTCAACAACTCGTGCACCTCATGTA
TGTCCACATAAAACAGCAAAACCAGGTGATAAAGATGACCGCAATTCACCTTATCCAATG
ATATCAGTTGAAGAAGCATTAAAAATAATTTTCAGCAACATTCGACCAATTTCGAAACCA
CAAACAATCAGAAGTCCAATAAATTGTCCACCATTTCGAGCAAGCATTAAAGATGGATAT
GCAGTGAAATCTTCATCAAAATCAACATTAAGAAAAGTCATTGGATCAATTTCAGCTGGT
GATTTTATAATTCAAGAAGATTTCAAAGAAGATGAATGTTATAAGATCAATACTGGTGCT
GCAGTACCAGATTTTGCTGATGCAATTGTTCAAGTTGAAGATACAAAATTAACAAAATCA
AATCCCGATGGAAGTGAAGCTGAAATTGAGCTGCTATCATTGCCATCAAAAAATTTAGAC
ATTCGTGAAATTGGAAGTGATTTGATGGAAAATCAAGAATTATTTACAACAAATGGACTT
TTGGATGTTGCAGAAAAAACAATTTTAGCATCTGTTGGACTTAATGCAGCTGAAAAGAAA
CCAAAAATTGCAATAATTTCAACAGGTGATGAATTACAAGATCCAGCATCAGGTGAACTT
CAAGAAGGTCACATTTATGACTCAAATACGACAATGTTGAAACTTTTATGTGAAAAATTC
AATTTTGATGTAAAATTCACGTGTATTGCAAAAGATGATTATGAATCATTGAAAAATGTT
GTAAGTGCTGCAATCAAAGAATGTCGTGTTATAATCAGTAGTGGTGGTGTATCAATGGGC
GACAAAGATTTCATCAAAAAAGTTCTTATTGATCTCGATTTTAAAATTCATTTTGGTAGA
GTCAATGTGAAACCAGGAAAACCAATGACTTTTGCGACATTAAATGAAAATTCATTTTTT
GCATTGCCAGGAAATCCAGTTAGTGCTTTTGTTACTTTTCACCTTTTTGTGCTTCCTGCT
TTGAGATTCATCAGCGGATATTCAGGAATTAAATGCATTTTGCCTTTAATCAATGTTGTA
CTTGAAGATTCTGAATATCATTTGGATGATCGTCCTGAATATGTAAGAGCAAAAATTTCT
TATGATCAAAATACAAATCAATTTACAGCTTTGGTCAATGCTAATCAAATTAGCAGCAGA
ATTGCAAGTCTTATAAATGCTGATGTTTTGCTAAAACTTCCAGGAAGAAAAGAATATGGA
AATTCAATTATAGAAAAAGGAACTAAATTGAAAGCAATGGTTATTAATCAATTTTTTATA
AGTTTTATTAATGAATAA
>g14845.t1 Gene=g14845 Length=685
MVDFTYGIITISDRCFRGETKDESGPKIKYLLQDEYNAHNIKQEIIPDDQNKIEEILILY
SDVLKINCIFTTGGTGCSPRDVTPEATRKIIHKEFPQLSMVMLLEGLRKTEFAALTRLIC
GIRNNSLIINFPGSVKAVTESFNAIKRLIPHAVDLICDIKDKTESVHKQIQSGTSKNATN
DFYREIKEKTNDSIDEVLKNYKQNSASNSESNLKRRNEDTEVEPKKIDNQKSNQSSTKPQ
TESSAAKEVPKPSTTRAPHVCPHKTAKPGDKDDRNSPYPMISVEEALKIIFSNIRPISKP
QTIRSPINCPPFRASIKDGYAVKSSSKSTLRKVIGSISAGDFIIQEDFKEDECYKINTGA
AVPDFADAIVQVEDTKLTKSNPDGSEAEIELLSLPSKNLDIREIGSDLMENQELFTTNGL
LDVAEKTILASVGLNAAEKKPKIAIISTGDELQDPASGELQEGHIYDSNTTMLKLLCEKF
NFDVKFTCIAKDDYESLKNVVSAAIKECRVIISSGGVSMGDKDFIKKVLIDLDFKIHFGR
VNVKPGKPMTFATLNENSFFALPGNPVSAFVTFHLFVLPALRFISGYSGIKCILPLINVV
LEDSEYHLDDRPEYVRAKISYDQNTNQFTALVNANQISSRIASLINADVLLKLPGRKEYG
NSIIEKGTKLKAMVINQFFISFINE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g14845.t1 | CDD | cd00886 | MogA_MoaB | 4 | 156 | 2.63444E-55 |
| 15 | g14845.t1 | CDD | cd00887 | MoeA | 284 | 675 | 8.35584E-119 |
| 13 | g14845.t1 | Gene3D | G3DSA:3.40.980.10 | Molybdenum cofactor biosynthesis proteins | 2 | 182 | 1.5E-51 |
| 11 | g14845.t1 | Gene3D | G3DSA:3.90.105.10 | Molybdopterin biosynthesis moea protein | 302 | 439 | 1.9E-88 |
| 10 | g14845.t1 | Gene3D | G3DSA:2.170.190.11 | Molybdopterin biosynthesis moea protein | 310 | 407 | 1.9E-88 |
| 12 | g14845.t1 | Gene3D | G3DSA:3.40.980.10 | Molybdenum cofactor biosynthesis proteins | 440 | 586 | 1.9E-88 |
| 14 | g14845.t1 | Gene3D | G3DSA:2.40.340.10 | - | 596 | 678 | 5.7E-18 |
| 22 | g14845.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 200 | 277 | - |
| 21 | g14845.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 212 | 228 | - |
| 23 | g14845.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 229 | 250 | - |
| 20 | g14845.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 263 | 277 | - |
| 5 | g14845.t1 | PANTHER | PTHR10192 | MOLYBDOPTERIN BIOSYNTHESIS PROTEIN | 275 | 676 | 1.8E-118 |
| 3 | g14845.t1 | Pfam | PF00994 | Probable molybdopterin binding domain | 7 | 150 | 1.2E-27 |
| 1 | g14845.t1 | Pfam | PF03453 | MoeA N-terminal region (domain I and II) | 301 | 433 | 1.7E-22 |
| 4 | g14845.t1 | Pfam | PF00994 | Probable molybdopterin binding domain | 444 | 582 | 2.7E-24 |
| 2 | g14845.t1 | Pfam | PF03454 | MoeA C-terminal region (domain IV) | 609 | 673 | 2.7E-8 |
| 17 | g14845.t1 | ProSitePatterns | PS01079 | Molybdenum cofactor biosynthesis proteins signature 2. | 518 | 552 | - |
| 19 | g14845.t1 | SMART | SM00852 | MoCF_biosynth_3a | 7 | 152 | 1.1E-18 |
| 18 | g14845.t1 | SMART | SM00852 | MoCF_biosynth_3a | 444 | 583 | 6.9E-35 |
| 9 | g14845.t1 | SUPERFAMILY | SSF53218 | Molybdenum cofactor biosynthesis proteins | 5 | 157 | 3.66E-35 |
| 6 | g14845.t1 | SUPERFAMILY | SSF63882 | MoeA N-terminal region -like | 277 | 435 | 1.18E-30 |
| 8 | g14845.t1 | SUPERFAMILY | SSF53218 | Molybdenum cofactor biosynthesis proteins | 441 | 587 | 1.16E-36 |
| 7 | g14845.t1 | SUPERFAMILY | SSF63867 | MoeA C-terminal domain-like | 595 | 676 | 2.88E-12 |
| 24 | g14845.t1 | TIGRFAM | TIGR00177 | molyb_syn: molybdenum cofactor synthesis domain | 6 | 146 | 8.0E-29 |
| 25 | g14845.t1 | TIGRFAM | TIGR00177 | molyb_syn: molybdenum cofactor synthesis domain | 440 | 579 | 3.7E-32 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006777 | Mo-molybdopterin cofactor biosynthetic process | BP |
| GO:0032324 | molybdopterin cofactor biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K15376 (gephyrin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
