General information for g15104.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Lipase 3.
Parent gene
- The parent gene g15104 is located on chr_4: 3912920..3914219 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15104 | g15104.t1 | TTS | g15104.t1 | 3912881 | 3912881 |
| chr_4 | g15104 | g15104.t1 | isoform | g15104.t1 | 3912920 | 3914219 |
| chr_4 | g15104 | g15104.t1 | exon | g15104.t1.exon1 | 3912920 | 3913285 |
| chr_4 | g15104 | g15104.t1 | cds | g15104.t1.CDS1 | 3912920 | 3913285 |
| chr_4 | g15104 | g15104.t1 | exon | g15104.t1.exon2 | 3913428 | 3914219 |
| chr_4 | g15104 | g15104.t1 | cds | g15104.t1.CDS2 | 3913428 | 3914219 |
| chr_4 | g15104 | g15104.t1 | TSS | g15104.t1 | 3914235 | 3914235 |
Sequences
>g15104.t1 Gene=g15104 Length=1158
ATGATCAGTTTAGTCAATTTTGTTAAATTTTCATCAATTTTAATAAGTTCAAGGAAAATT
TCATTATCAAAACAATCAGATGAAGTGACCAAAATCATCACAAACTCAGGGTATAAAGCT
GAAGTACATAAAGTGAAAACAATTGACGATTATGAGCTAACAGTGCATCAAATTCTACCT
CAACAAATAATAGATCGCAAAAAGTGTGTTTTTTTCATGCATGGATTATTTCGAAACTCA
GCGGATTTTCTAGCAACTGGATCACAAATTGCGTTGCCTTATCTTTTAGCTGATCATGGT
TTTGATGTGTTTTTAGGCAATGCAAGGGGAACAAAATACTCAACTAAAAATTTTAAATAT
GACAATAAATCAAAAGAATTTTGGAACTTTTCATGGGAAGAAATTGGACTTTATGACTTA
CCACCAATGTTCAATTTTTCATTAGAAAAAAGTGAAACCGAAAAAATCAATTATGTTGGA
CATTCACAAGGTTGCACAGCGGCATTAGTTTTATTATCTGAAAATCCAGAATGGAATTCA
AAATTTACTCAATTGCATCTCTTGACACCAGCTGTTTTTCTTCATCATGCTAAATCACCT
GCTTATAAAATTGGCATTAGATTACAAAATTTTTTGACAAGATTACATAAAATTGACATT
GGAATGCTTTTGAGATTTGGCAATCAAATGCAGAAATTTAGTAAAAATAATCCAAAAACT
ATATTGGATTTGTATAAACAAATAACTTGCAAAATTGTTGGTACAAATAAAGGAGAAATT
CAATTATCTTTGGAAGTACTAAAATTGCTTTCCGATTTTATGTCACCAACTGTCAGTGCA
AATCAATTACGTCACTTTTTACAACTCTATGAAAGTGGAAAATTCCAAAAATTTGATTAC
AAAACTCGAAATATTTTAAAATATGGATCAAATGAACCACCTGAATTTGAACTGAAAAAT
ATTAAAGTTTCTACATATCTTTATCATGCTGAAATGGATGCTTTAGTTGATACAAAAAGT
GTTGAACAATTAGCACAAATATTACCAAATGTTAAGAAATTAACTGTTGTACCTGATTAT
AATCATCTTGATGTGATGCTTGGAAAAAATTGCAGAAAAGATTTATATGAAAATATGTTA
AAAGATCTTATTGAATAA
>g15104.t1 Gene=g15104 Length=385
MISLVNFVKFSSILISSRKISLSKQSDEVTKIITNSGYKAEVHKVKTIDDYELTVHQILP
QQIIDRKKCVFFMHGLFRNSADFLATGSQIALPYLLADHGFDVFLGNARGTKYSTKNFKY
DNKSKEFWNFSWEEIGLYDLPPMFNFSLEKSETEKINYVGHSQGCTAALVLLSENPEWNS
KFTQLHLLTPAVFLHHAKSPAYKIGIRLQNFLTRLHKIDIGMLLRFGNQMQKFSKNNPKT
ILDLYKQITCKIVGTNKGEIQLSLEVLKLLSDFMSPTVSANQLRHFLQLYESGKFQKFDY
KTRNILKYGSNEPPEFELKNIKVSTYLYHAEMDALVDTKSVEQLAQILPNVKKLTVVPDY
NHLDVMLGKNCRKDLYENMLKDLIE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g15104.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 17 | 384 | 0 |
| 2 | g15104.t1 | PANTHER | PTHR11005:SF127 | LIPASE-RELATED | 19 | 383 | 0 |
| 3 | g15104.t1 | PANTHER | PTHR11005 | LYSOSOMAL ACID LIPASE-RELATED | 19 | 383 | 0 |
| 6 | g15104.t1 | PIRSF | PIRSF000862 | Steryl_ester_lip | 1 | 385 | 0 |
| 1 | g15104.t1 | Pfam | PF00561 | alpha/beta hydrolase fold | 70 | 368 | 0 |
| 4 | g15104.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 29 | 380 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
