Gene loci information

Transcript annotation

  • This transcript has been annotated as Fatty acid synthase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15115 g15115.t1 isoform g15115.t1 3942890 3949374
chr_4 g15115 g15115.t1 exon g15115.t1.exon1 3942890 3943302
chr_4 g15115 g15115.t1 cds g15115.t1.CDS1 3942890 3943302
chr_4 g15115 g15115.t1 exon g15115.t1.exon2 3943355 3943746
chr_4 g15115 g15115.t1 cds g15115.t1.CDS2 3943355 3943746
chr_4 g15115 g15115.t1 exon g15115.t1.exon3 3943799 3944148
chr_4 g15115 g15115.t1 cds g15115.t1.CDS3 3943799 3944148
chr_4 g15115 g15115.t1 exon g15115.t1.exon4 3944235 3948615
chr_4 g15115 g15115.t1 cds g15115.t1.CDS4 3944235 3948615
chr_4 g15115 g15115.t1 exon g15115.t1.exon5 3948697 3948900
chr_4 g15115 g15115.t1 cds g15115.t1.CDS5 3948697 3948900
chr_4 g15115 g15115.t1 exon g15115.t1.exon6 3948959 3949374
chr_4 g15115 g15115.t1 cds g15115.t1.CDS6 3948959 3949374
chr_4 g15115 g15115.t1 TSS g15115.t1 NA NA
chr_4 g15115 g15115.t1 TTS g15115.t1 NA NA

Sequences

>g15115.t1 Gene=g15115 Length=6156
ATGAGTGAAAAATGTGATGATGTGGTTGTGACTGGCATTGCTGGTCGTTTTCCAAAATCT
CGAAATATAAAAGAATTTTCTGAAAATTTATTTAATAAAGTGGATATGACTGATGACAAA
GAAGTTCATTGGAAGTATATTCTTGAAAATATTCCAATGCGAAGTGGAAAAATTACGGAC
ATTGATAAATTTGATGCTTCATTCTTTTCTATGATGAATAATCAAGCAAAATTTACTGAT
CCACAATTGAGAATTTTATTTGAACATGTTTATGAAGCAATTTTAGATGCAGGAATTTCT
CCTCAATCTTTAATTGGTAGCAATACTGGTGTCATCATTGGTTGCAGTATGTCAGAAGCC
ATGATAAGTTATACAAAAGGAACATATGTAGCCGAAAATGGTGTTGCAACTTATAACAAT
GGACCATTCTTCCTTGCCAGTAAAATTTCTTATACTTTTGGTTTTCGTGGACCCGCACTT
ATTATTGATACAGCTTGTTCTAGTGCTGCAAGTGCCTTGAATTGTGCTTTTAAATATATG
AAGCAAAATGAATGTGATGCTGCAGTTGTAGCTGGTTCTCATCTTAATTTGAGTCCACGA
ATGTTTGTAGAATTTTCTGGTTTGAACGTTTTATCACCTGATGGAATTTCTAAAGTTTTT
GATGAAGATTCAAAAGGTTTTGTTCGTTCGGACACAATTTCCGCTGTATTTCTTCAAAAA
CGCAAAGATGCTAAACGAATTTATGCTCAAATTGTTCATTCATTATCAAATAATGATGGA
TTTAAACATGAAGGAATTCTTTTACCATCAAAAGAAGTTCAACAGCTACTCATGGAAAAT
TTATATAAAGAAGCCAATATTGACCCAAATGAAATCAATTATTTTGAGGCTCATGCAACA
GGCACTTTTAAGGGAGATTTTCAAGAAATTGAAGCAGTTGATGAAGTTTTTTGCAAGAAA
AATTGTCAAAATAAGTTAACAATTGGAAGTGTTAAGTCTAACATGGGACATAGTGAGGCA
GCTAGTGCAATGGCTTCTTTAGCTAAAATTTTAATAGCTTTTGAAAATGGAAAATTTCCA
CCAAATATCAATTTGTATAAACTTCGCAATGATATTCCAGCTTTTGTTGAAGGAAGAATT
AAAGTTGCAAATGATGCTGTGCCATTAATTTCTGAATATATTTCAATGAATAGCTTTGGC
TTTGGTGGTTATAATGTTCATCTTTTATTCAAACGAAATTCAAAGGAAAAAATTATCAAT
AACTATGGTGAAATGGAAAGAATGGTTTTGTGGTCAGGAAGAACTGAAGATGCTGTTCAT
TTAATATTTGATGATATCACGAGTCAATCACTTGATATCGAATATATTGCACTACTTCAA
AACACTCAAATTCTCACACCAAATACAAATTGTTATCGAGGTTTCGGAATGTTTAAGAAT
AGTGAAGAAAATGCAATTTGCATCGATAGAAATGTTCAAAAATTTGATGGAACTCGTCGA
AAAATTGTTTTTGCTTACGCTGGTATGGGATCACAATGGTATAAAATGGGACAAGATTTA
ATGACTATTCAATTGTTTGCTAGTTCGATTGAAAAATGTCACGAAATTTTACTGGAAAAT
GGAATTGATTTAAAATCAATTTTAAACTCAAATGATGAGAATATTTATGAAAATGTTTTA
AATTCTTATGTTGGAATTATTTCTATACAAATAGCTTTAACTGATGTTCTACATACTCTT
AATATTAAACCAGATTTTATTGTTGGTCATTCAGTAGGTGAAATAGCTTGTGCTTATGCT
GATGGTTGTTTAACAATGAAAGAAGCTTTGAAAATTGCATATTTGAGGGCTAAAATTACT
CTTGATTTTAACATAAATGGCGGAGCAATGGCAGTTGTTGGAATGAGTTGTGAAGAACTC
GAAAAAGTTTTGCCATATGAAATTGACATTGCTTGTTATAATACAAAAGAATTACAAACA
ATTAGTGGCAATAAAAAAGAAATTTGTGAGTTTGTCGATGAATTAAAATCACAAAATATT
TTTGCAAAAGAAATTGAATGTGCTGGAGTTCCTTTCCATAGTCGTCACATTTCTGTTGTA
GCTGAAAAATTTGAACAAAATTTGCAAGATTTGTTAAAAACACCAAAAATGCGATCACAA
AAATGGATCACAAGCACTTATAATCAAGAAAATGAGCAGAATAAAATTTGTGGCATAAAA
TATCAAATTGATAATGTTAAAAATCCAGTCTATTTTGATAAAGCTCTTGAAAATCTTCCT
AAAAATTCTTTGATTATCGAAATTTCTCCACACGGTTTATTAAAATCATTTTTTAAATTT
TCTTCAAATGAAATTATTTATGAAAGATTAATGAACAAAACTTCAATAAGTCACAAAGAT
TTTTTCATGCAATCTATTGGAAAAATATTTCAACATGGAGTTGATTTGGATGTTAGTAAA
TTTTATCCTGCTATTGAATTTCCAGTTTCTCGAGGTACTTCAATGATTTCACCAATTATC
AAATGGAATCATCAAGATAGTCATTTTGTGCCAATATTTGACCATGATTTTGAATTAAGT
CGTTGTTCAAAAATAATCAACTTTAAATCTCCAAAATTTTCTTATGTTTATGATCACGTT
ATTGATGGAAAAGCAGTAATTCCAGCAGTATTTTGGATACACAATATATGGAAATATTTT
GCAGCGTTATGTGAAAGAAAATGGTTTGAAACTAAAATAATTTTAGAAAAAGTTGAGTGT
GTTCAAATAGCTTATCCGGATCAAGAAGTTAAAATGACTTTAAACATGAACAGAAAAACT
GGAAATGTTGAAGTTCATTGTAATAACAATCTCGTAATGAAAGCCATTGCAAAATGTGAC
GATAATTTACAAATTGATGAAATTGAAAATTTCAAACATTCAGATGATGGTGTTGTATTG
ACTAAAAATGTTTTTTATAAATTTGTTCGCATTCGTGGTTATCATTATAAAGAAAAATTT
CAACTAGTTCATGAAATTAGCAATGAATTAAAAGGCAAAGTTAAATGGGACAATAATTGG
GCAACTTTTGCTGATACACTTTTTCAAATCATGATAATTAATAATAATTTTTTAAATCAA
ATTGGATTGCCAAAAAAAATTGAGAAAATTTCTTTCGATCCAATTGTTCATAATAAAATT
ATTGAGCGATTAAAAATAGACAATCAATCAGAAATTCTTGTACCTATTGAAGGAAGTTAT
GATTTAGGTACAATAAAATGTGGTGGTGTTGAAATGTATGAACCTTCATTAATTATGATC
AACAGACAAGAGCAAAAAAATTTAACTCATGAATTTTACAAATTTATTTCCTTTGAAAAT
GATCATAACAATTTTCAACTTTCTGATGCTTTAAAGATTTTTACTACAATTATGATTGAT
AGAAATCCCAAGCAAACATTTAATTTAATAGAAATCAATGATGGAGGTTCTGACTTTTGG
GCTCCAATCCTTGAAATACAAAGTCGTTTGCTTCATAATATTTTCAATATTAAAGTTTTA
ACAAAGACAGAGCAAAAAATTAATAATGTAGAAGTTATAACTGATCAAGATGTTTCAATG
TTCAACAATATCGATGTCATTTACACCAAACATAAATTAAATGACATTGAATTTATAGAA
AAAATTTCAAAAGCGTTATGTAAAGATGGAATTTTTATAACACTTGAAGAATTCAATGTT
AAAAAATGTAACGAAAAAATTGAAATTTTATCAGAATTAAATTTAGAAAGCAATCAACGT
TTAATTATGACAAGAATCAAAAAAGAAGAAATGCAAATCAAACCAATAATTTTTAAAATT
ACCCCAATTATGTCAAATTGGTTAGAAAATTTGCAACATGAAATTCAAAAACTTTCTAAA
CAAATCGACAATACAATTTTGTTGTATTCACAAGAACCAAATGTTGGACTTCTTGGATTT
TATAATTGTTTGCGTTTAGAATTTCCAGAAATTAATATTTTATGTTTCATTATTGATGAT
AAAAATGCACCAGAATTTGATATTGAAAATTCGTTTTATAAGAAGCAATTGTTGAAAGGT
TTCAAGAAAAATATTTTGAAAAATAATCAATGGGGAATGTTTTGTCATGTAAATACAAAT
TTTTCAATTGAACCTTTGCCATATAAAGGGCAATGTTTTGCAAATTACAACAGAAGAGGC
AATATTAACACTCTTAAATGGCATCAAGGACCTTTGACTGTTATTGATTCACAAGTCAAT
TCTGATTTGATTAAAATACAATATGTGGCACTTAATTTCAAAGACATTGTTTATGCTTAT
GGTTACATTCCTGATGGATTAAATTTAATGAAAGAATGTTCATTAGGATTAGAACTTGGA
GGTATTCGAATTAATACTGGTAAAAAAGTTGCTATAATGACAAGAAATATTGCTGGAATA
ACTTCATATTTTGATGCGAGTGCCAAAAACAATGCAATCATTCTTGAAATTGACAATGAA
TTGGAATTAGTTGATGTAACATCATCATTACTTATTTATTTCACTGTCTATTATTCATTC
TTTTATGCAACAAAAATAGAAAAAGGAAAATCAATTTTGATTCACAGTGGTGCTGGTGGC
GTTGGACAGGCAGCTCTTTATACTGCATTTGCAAATGATTTAGAAGTTTTTACCACTGTC
GGTACTGAAGAGAAGAAGAAATTTTTACTTGAAAATTTCCCTAAATTGAAACCTGAAAAT
ATTGGAAATTCACGAAATACTTCTTTTTACAAAATGATTATGACACAAACTAAAGGACGA
GGAGTTGATTATGTTTTGAATTCTCTAAGTGGTGATAAAATGATTGCATCATTAGATTGT
GTAGCAGAAAATGGATGCTTTTTAGAAATTGGTCAAGCTGACATTATGTTGGGAACAAAA
ATTGATGTGAAGTTTTTGGAGAAAAATATTTTAATAAAATCAGTTAGAGCAGATTTGATG
GATTTTTCAAAAATACCTAAAGCATTATTTTATGAAATCCTTCAAGATATTAAAGCAGAA
AAAATCAAACCACCAAGCAGAACTGTTTTTAATGCAAATGATGTTGTCAAAGCATTTCAA
CACATGTCTACTGGTAATCATATTGGTAAAGTAATGTTGAAAATTCGTGAAAATTTAAAT
GATGAAGAAACTTTACCGATTTCTGTGACTCCACGTTTCTATTGCAATCCTGATCGATCT
TACATAATTGTTGGAGGTTTAGGTGGACTTGGTCTTGAATTTTCTGAATGGCTTATTGGA
CGAAAATGTCGTAAACTTATTTTTAACTCAAGAAGAGGCATAAGCAATCAATATCAGCTT
TTTAAAATCAATTATTGGAAATCTCTTGGTGTGAAAATTATTATCAATACATCTGATGTC
ACAACTGAAGCAGGATGTAAAGAATTAATCAAAGCAGCAAATAGTCTTGGTGATGTTGAC
GGAATTTTCAATTTTGCTGCCATTATTAAAGATGGGCTATTTACAAATCAGACTTTAGAA
ACTTTTAATCAAACAATGATTCCAAAAGCTATTATAACTAAATATCTACATGAATTATCA
TTAAAACTTTGTCCAAAATTGAGACATTTTGTTGTTTATTCAAGTATGTCATGTGGCAAA
GGGACAGCAGGACAAACTAATTATGGAATGGCAAATTCGATAATGGAAGAAATCATACTT
AAGCGATATGAGATGGGTCTTTCAGCCAAAGTTATGCAATGGGGACCAATTGCAGATGTT
GGTTTACTTGAGAATATGATGGGACAAACAGAAGGAAGTAAATATAATTTTAAAATTCCG
ACACAGTCGCTTGGTTCCTTCTTAGAATATCATGATCATCTTCTGTTATATCCAGAACCG
ATTGTTGCGTGCGCAGTGTATAATACTAATAAAAAATTATATGAAGGCAAAAAAGGATTT
ATTGAAATCATCATGAACTTATTTAACATTGAAGATCGTTCATCATTTTCTATGAACTTA
ACATTCTCTCAACTTGGTGTTGATTCTTTAGCTGGAATAGAAATACAAAATAGAATAGAA
AGAGAATTTGGTGTTAACTTTACAATACAAGAATTAAGAAGTATGACATTAGGAGAAATC
GAAACAAGAATTGAAAAGGAAAGAAAGAATTTATAA

>g15115.t1 Gene=g15115 Length=2051
MSEKCDDVVVTGIAGRFPKSRNIKEFSENLFNKVDMTDDKEVHWKYILENIPMRSGKITD
IDKFDASFFSMMNNQAKFTDPQLRILFEHVYEAILDAGISPQSLIGSNTGVIIGCSMSEA
MISYTKGTYVAENGVATYNNGPFFLASKISYTFGFRGPALIIDTACSSAASALNCAFKYM
KQNECDAAVVAGSHLNLSPRMFVEFSGLNVLSPDGISKVFDEDSKGFVRSDTISAVFLQK
RKDAKRIYAQIVHSLSNNDGFKHEGILLPSKEVQQLLMENLYKEANIDPNEINYFEAHAT
GTFKGDFQEIEAVDEVFCKKNCQNKLTIGSVKSNMGHSEAASAMASLAKILIAFENGKFP
PNINLYKLRNDIPAFVEGRIKVANDAVPLISEYISMNSFGFGGYNVHLLFKRNSKEKIIN
NYGEMERMVLWSGRTEDAVHLIFDDITSQSLDIEYIALLQNTQILTPNTNCYRGFGMFKN
SEENAICIDRNVQKFDGTRRKIVFAYAGMGSQWYKMGQDLMTIQLFASSIEKCHEILLEN
GIDLKSILNSNDENIYENVLNSYVGIISIQIALTDVLHTLNIKPDFIVGHSVGEIACAYA
DGCLTMKEALKIAYLRAKITLDFNINGGAMAVVGMSCEELEKVLPYEIDIACYNTKELQT
ISGNKKEICEFVDELKSQNIFAKEIECAGVPFHSRHISVVAEKFEQNLQDLLKTPKMRSQ
KWITSTYNQENEQNKICGIKYQIDNVKNPVYFDKALENLPKNSLIIEISPHGLLKSFFKF
SSNEIIYERLMNKTSISHKDFFMQSIGKIFQHGVDLDVSKFYPAIEFPVSRGTSMISPII
KWNHQDSHFVPIFDHDFELSRCSKIINFKSPKFSYVYDHVIDGKAVIPAVFWIHNIWKYF
AALCERKWFETKIILEKVECVQIAYPDQEVKMTLNMNRKTGNVEVHCNNNLVMKAIAKCD
DNLQIDEIENFKHSDDGVVLTKNVFYKFVRIRGYHYKEKFQLVHEISNELKGKVKWDNNW
ATFADTLFQIMIINNNFLNQIGLPKKIEKISFDPIVHNKIIERLKIDNQSEILVPIEGSY
DLGTIKCGGVEMYEPSLIMINRQEQKNLTHEFYKFISFENDHNNFQLSDALKIFTTIMID
RNPKQTFNLIEINDGGSDFWAPILEIQSRLLHNIFNIKVLTKTEQKINNVEVITDQDVSM
FNNIDVIYTKHKLNDIEFIEKISKALCKDGIFITLEEFNVKKCNEKIEILSELNLESNQR
LIMTRIKKEEMQIKPIIFKITPIMSNWLENLQHEIQKLSKQIDNTILLYSQEPNVGLLGF
YNCLRLEFPEINILCFIIDDKNAPEFDIENSFYKKQLLKGFKKNILKNNQWGMFCHVNTN
FSIEPLPYKGQCFANYNRRGNINTLKWHQGPLTVIDSQVNSDLIKIQYVALNFKDIVYAY
GYIPDGLNLMKECSLGLELGGIRINTGKKVAIMTRNIAGITSYFDASAKNNAIILEIDNE
LELVDVTSSLLIYFTVYYSFFYATKIEKGKSILIHSGAGGVGQAALYTAFANDLEVFTTV
GTEEKKKFLLENFPKLKPENIGNSRNTSFYKMIMTQTKGRGVDYVLNSLSGDKMIASLDC
VAENGCFLEIGQADIMLGTKIDVKFLEKNILIKSVRADLMDFSKIPKALFYEILQDIKAE
KIKPPSRTVFNANDVVKAFQHMSTGNHIGKVMLKIRENLNDEETLPISVTPRFYCNPDRS
YIIVGGLGGLGLEFSEWLIGRKCRKLIFNSRRGISNQYQLFKINYWKSLGVKIIINTSDV
TTEAGCKELIKAANSLGDVDGIFNFAAIIKDGLFTNQTLETFNQTMIPKAIITKYLHELS
LKLCPKLRHFVVYSSMSCGKGTAGQTNYGMANSIMEEIILKRYEMGLSAKVMQWGPIADV
GLLENMMGQTEGSKYNFKIPTQSLGSFLEYHDHLLLYPEPIVACAVYNTNKKLYEGKKGF
IEIIMNLFNIEDRSSFSMNLTFSQLGVDSLAGIEIQNRIEREFGVNFTIQELRSMTLGEI
ETRIEKERKNL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
25 g15115.t1 CDD cd00833 PKS 6 409 1.49232E-130
26 g15115.t1 CDD cd05195 enoyl_red 1424 1713 9.65768E-74
24 g15115.t1 Coils Coil Coil 1288 1308 -
20 g15115.t1 Gene3D G3DSA:3.40.47.10 - 5 412 4.4E-122
18 g15115.t1 Gene3D G3DSA:3.30.70.3290 - 426 848 3.5E-139
23 g15115.t1 Gene3D G3DSA:3.40.366.10 - 498 813 3.5E-139
19 g15115.t1 Gene3D G3DSA:3.10.129.110 - 863 1106 4.1E-36
17 g15115.t1 Gene3D G3DSA:3.40.50.720 - 1286 1966 2.5E-198
22 g15115.t1 Gene3D G3DSA:3.90.180.10 - 1381 1733 2.5E-198
21 g15115.t1 Gene3D G3DSA:1.10.1200.10 - 1975 2050 3.9E-13
8 g15115.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 5 2046 0.0
9 g15115.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 5 2046 0.0
6 g15115.t1 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 244 2.0E-54
1 g15115.t1 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 248 365 1.2E-33
7 g15115.t1 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 370 475 1.0E-22
4 g15115.t1 Pfam PF00698 Acyl transferase domain 503 776 2.6E-53
3 g15115.t1 Pfam PF13602 Zinc-binding dehydrogenase 1585 1712 3.5E-12
5 g15115.t1 Pfam PF08659 KR domain 1740 1919 1.3E-36
2 g15115.t1 Pfam PF00550 Phosphopantetheine attachment site 1993 2043 4.1E-7
27 g15115.t1 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 -
32 g15115.t1 ProSiteProfiles PS50075 Carrier protein (CP) domain profile. 1971 2051 10.398
30 g15115.t1 SMART SM00825 Beta-ketoacyl synthase 8 413 9.9E-85
29 g15115.t1 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 505 801 3.3E-19
28 g15115.t1 SMART SM00829 PKS_ER_names_mod 1400 1713 7.6E-68
31 g15115.t1 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1739 1920 2.4E-15
11 g15115.t1 SUPERFAMILY SSF53901 Thiolase-like 6 411 2.08E-61
10 g15115.t1 SUPERFAMILY SSF52151 FabD/lysophospholipase-like 501 779 3.4E-40
16 g15115.t1 SUPERFAMILY SSF55048 Probable ACP-binding domain of malonyl-CoA ACP transacylase 626 683 2.62E-6
14 g15115.t1 SUPERFAMILY SSF50129 GroES-like 1420 1535 5.34E-5
12 g15115.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1508 1655 8.2E-28
13 g15115.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1737 1967 1.39E-27
15 g15115.t1 SUPERFAMILY SSF47336 ACP-like 1981 2045 2.22E-9

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity MF
GO:0016740 transferase activity MF
GO:0006633 fatty acid biosynthetic process BP
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values