Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Lysosomal thioesterase PPT2-like protein.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15371 g15371.t6 TSS g15371.t6 5146872 5146872
chr_4 g15371 g15371.t6 isoform g15371.t6 5147014 5149238
chr_4 g15371 g15371.t6 exon g15371.t6.exon1 5147014 5147043
chr_4 g15371 g15371.t6 cds g15371.t6.CDS1 5147014 5147043
chr_4 g15371 g15371.t6 exon g15371.t6.exon2 5147281 5147530
chr_4 g15371 g15371.t6 cds g15371.t6.CDS2 5147281 5147530
chr_4 g15371 g15371.t6 exon g15371.t6.exon3 5147622 5147760
chr_4 g15371 g15371.t6 cds g15371.t6.CDS3 5147622 5147760
chr_4 g15371 g15371.t6 exon g15371.t6.exon4 5149227 5149238
chr_4 g15371 g15371.t6 cds g15371.t6.CDS4 5149227 5149236
chr_4 g15371 g15371.t6 TTS g15371.t6 5149938 5149938

Sequences

>g15371.t6 Gene=g15371 Length=431
ATGATAATTATTGCAGAACGCATTAAATTGCATCATCCTGGAACAGAAGTTTACTTAATT
GACAAATTTAATAATTGGGGAAGTCTTGAAAATGCTTTAAGTCAAATTGATTCATTTTTT
GATGATTTTGACGAAATTTTCAAAAAGCATCCTGAAGGAGTACACGTTCTTGGTTATTCA
CAAGGTGGACTTTTAGCCAGAGCTTTAATTCAATTTTATAAAAATCACAATGTTAAGAAA
TTTATTTCACTGAGCAGTCCACAAGCTGGTCAATTTGGATCTGCTTTCCTTCATTTAATT
TTTCCTACACTGGTTGCTAACAATGCTTATGAACTTTTTTATTCTCGTCTTGGCCAAAGA
ACTTCAGTTGGCAATTATTGGAATGATCCCCATCAAAGACCTTTGTATCTTAAATATAGT
AATTTTCTACC

>g15371.t6 Gene=g15371 Length=143
MIIIAERIKLHHPGTEVYLIDKFNNWGSLENALSQIDSFFDDFDEIFKKHPEGVHVLGYS
QGGLLARALIQFYKNHNVKKFISLSSPQAGQFGSAFLHLIFPTLVANNAYELFYSRLGQR
TSVGNYWNDPHQRPLYLKYSNFL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g15371.t6 Gene3D G3DSA:3.40.50.1820 - 1 143 0
2 g15371.t6 PANTHER PTHR11247 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 4 143 0
3 g15371.t6 PANTHER PTHR11247:SF27 LYSOSOMAL THIOESTERASE PPT2 4 143 0
1 g15371.t6 Pfam PF02089 Palmitoyl protein thioesterase 4 143 0
4 g15371.t6 SUPERFAMILY SSF53474 alpha/beta-Hydrolases 4 143 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

## Warning: Removed 2 row(s) containing missing values (geom_path).

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016790 thiolester hydrolase activity MF
GO:0008474 palmitoyl-(protein) hydrolase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values