General information for g15371.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Lysosomal thioesterase PPT2-like protein.
Parent gene
- The parent gene g15371 is located on chr_4: 5147630..5149830 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15371 | g15371.t8 | TSS | g15371.t8 | 5146872 | 5146872 |
| chr_4 | g15371 | g15371.t8 | isoform | g15371.t8 | 5147014 | 5149830 |
| chr_4 | g15371 | g15371.t8 | exon | g15371.t8.exon1 | 5147014 | 5147043 |
| chr_4 | g15371 | g15371.t8 | cds | g15371.t8.CDS1 | 5147014 | 5147043 |
| chr_4 | g15371 | g15371.t8 | exon | g15371.t8.exon2 | 5147281 | 5147530 |
| chr_4 | g15371 | g15371.t8 | cds | g15371.t8.CDS2 | 5147281 | 5147530 |
| chr_4 | g15371 | g15371.t8 | exon | g15371.t8.exon3 | 5147622 | 5147760 |
| chr_4 | g15371 | g15371.t8 | cds | g15371.t8.CDS3 | 5147622 | 5147760 |
| chr_4 | g15371 | g15371.t8 | exon | g15371.t8.exon4 | 5149227 | 5149343 |
| chr_4 | g15371 | g15371.t8 | cds | g15371.t8.CDS4 | 5149227 | 5149343 |
| chr_4 | g15371 | g15371.t8 | exon | g15371.t8.exon5 | 5149610 | 5149830 |
| chr_4 | g15371 | g15371.t8 | cds | g15371.t8.CDS5 | 5149610 | 5149649 |
| chr_4 | g15371 | g15371.t8 | TTS | g15371.t8 | 5149938 | 5149938 |
Sequences
>g15371.t8 Gene=g15371 Length=757
ATGATAATTATTGCAGAACGCATTAAATTGCATCATCCTGGAACAGAAGTTTACTTAATT
GACAAATTTAATAATTGGGGAAGTCTTGAAAATGCTTTAAGTCAAATTGATTCATTTTTT
GATGATTTTGACGAAATTTTCAAAAAGCATCCTGAAGGAGTACACGTTCTTGGTTATTCA
CAAGGTGGACTTTTAGCCAGAGCTTTAATTCAATTTTATAAAAATCACAATGTTAAGAAA
TTTATTTCACTGAGCAGTCCACAAGCTGGTCAATTTGGATCTGCTTTCCTTCATTTAATT
TTTCCTACACTGGTTGCTAACAATGCTTATGAACTTTTTTATTCTCGTCTTGGCCAAAGA
ACTTCAGTTGGCAATTATTGGAATGATCCCCATCAAAGACCTTTGTATCTTAAATATAGT
AATTTTCTACCTTATGTAAATAATGAAATCTTATGTACAAATTCTTCACAATTTCGTGAT
AATCTATTAAAGCTAGAAAAAATGATTCTCATTGGTGGTCCTGATGATGGTGGTAATAAT
AACTCCATGGGAAAGCGCACATTTTGGTTTTTATGATCAAAATTTAACAGTAATACCTTT
AAGAGAGCGACAATTTTATGTAGAAGATGCAATTGGTTTAAAGACTTTAGACGAACAAAA
GAAACTTGAACTTGTGACTGTTCCACATATTATACATATAGCATGGCACTTAAATGTAAC
GCTCATCGATGAAATCATCGTTCCTAGATTAGACTGA
>g15371.t8 Gene=g15371 Length=191
MIIIAERIKLHHPGTEVYLIDKFNNWGSLENALSQIDSFFDDFDEIFKKHPEGVHVLGYS
QGGLLARALIQFYKNHNVKKFISLSSPQAGQFGSAFLHLIFPTLVANNAYELFYSRLGQR
TSVGNYWNDPHQRPLYLKYSNFLPYVNNEILCTNSSQFRDNLLKLEKMILIGGPDDGGNN
NSMGKRTFWFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g15371.t8 | Gene3D | G3DSA:3.40.50.1820 | - | 1 | 181 | 0 |
| 2 | g15371.t8 | PANTHER | PTHR11247 | PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 | 4 | 177 | 0 |
| 3 | g15371.t8 | PANTHER | PTHR11247:SF27 | LYSOSOMAL THIOESTERASE PPT2 | 4 | 177 | 0 |
| 1 | g15371.t8 | Pfam | PF02089 | Palmitoyl protein thioesterase | 4 | 177 | 0 |
| 4 | g15371.t8 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 4 | 177 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
## Warning: Removed 1 row(s) containing missing values (geom_path).
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016790 | thiolester hydrolase activity | MF |
| GO:0008474 | palmitoyl-(protein) hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
