Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Lysosomal thioesterase PPT2-like protein.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15371 g15371.t9 TSS g15371.t9 5146872 5146872
chr_4 g15371 g15371.t9 isoform g15371.t9 5147014 5149830
chr_4 g15371 g15371.t9 exon g15371.t9.exon1 5147014 5147043
chr_4 g15371 g15371.t9 cds g15371.t9.CDS1 5147014 5147043
chr_4 g15371 g15371.t9 exon g15371.t9.exon2 5147281 5147760
chr_4 g15371 g15371.t9 cds g15371.t9.CDS2 5147281 5147547
chr_4 g15371 g15371.t9 exon g15371.t9.exon3 5149227 5149339
chr_4 g15371 g15371.t9 exon g15371.t9.exon4 5149610 5149830
chr_4 g15371 g15371.t9 TTS g15371.t9 5149938 5149938

Sequences

>g15371.t9 Gene=g15371 Length=844
ATGATAATTATTGCAGAACGCATTAAATTGCATCATCCTGGAACAGAAGTTTACTTAATT
GACAAATTTAATAATTGGGGAAGTCTTGAAAATGCTTTAAGTCAAATTGATTCATTTTTT
GATGATTTTGACGAAATTTTCAAAAAGCATCCTGAAGGAGTACACGTTCTTGGTTATTCA
CAAGGTGGACTTTTAGCCAGAGCTTTAATTCAATTTTATAAAAATCACAATGTTAAGAAA
TTTATTTCACTGAGCAGTCCACAAGCTGGTCAATTTGGATGTAAGTTTTTATTTTAATTA
AATTTTTTTAAATTTATAAAATTGAATTTTTAACATTGCCCAAAAAAATTTCTCATTTTT
TGTAATTTTAGCTGCTTTCCTTCATTTAATTTTTCCTACACTGGTTGCTAACAATGCTTA
TGAACTTTTTTATTCTCGTCTTGGCCAAAGAACTTCAGTTGGCAATTATTGGAATGATCC
CCATCAAAGACCTTTGTATCTTAAATATAGTAATTTTCTACCTTATGTAAATAATGAAAT
CTTATGTACAAATTCTTCACAATTTCGTGATAATCTATTAAAGCTAGAAAAAATGATTCT
CATTGGTGGTCCTGATGATGGTGTAATAACTCCATGGGAAAGCGCACATTTTGGTTTTTA
TGATCAAAATTTAACAGTAATACCTTTAAGAGAGCGACAATTTTATGTAGAAGATGCAAT
TGGTTTAAAGACTTTAGACGAACAAAAGAAACTTGAACTTGTGACTGTTCCACATATTAT
ACATATAGCATGGCACTTAAATGTAACGCTCATCGATGAAATCATCGTTCCTAGATTAGA
CTGA

>g15371.t9 Gene=g15371 Length=98
MIIIAERIKLHHPGTEVYLIDKFNNWGSLENALSQIDSFFDDFDEIFKKHPEGVHVLGYS
QGGLLARALIQFYKNHNVKKFISLSSPQAGQFGCKFLF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g15371.t9 Gene3D G3DSA:3.40.50.1820 - 1 98 0
2 g15371.t9 PANTHER PTHR11247 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 4 94 0
3 g15371.t9 PANTHER PTHR11247:SF27 LYSOSOMAL THIOESTERASE PPT2 4 94 0
1 g15371.t9 Pfam PF02089 Palmitoyl protein thioesterase 4 95 0
4 g15371.t9 SUPERFAMILY SSF53474 alpha/beta-Hydrolases 4 97 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016790 thiolester hydrolase activity MF
GO:0008474 palmitoyl-(protein) hydrolase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values