General information for g15397.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Esterase 6.
Parent gene
- The parent gene g15397 is located on chr_4: 5323333..5323755 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_4 | g15397 | g15397.t1 | isoform | g15397.t1 | 5317464 | 5323755 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon1 | 5317464 | 5317653 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS1 | 5317464 | 5317653 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon2 | 5317914 | 5318847 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS2 | 5317914 | 5318847 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon3 | 5318937 | 5319146 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS3 | 5318937 | 5319146 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon4 | 5320383 | 5320437 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS4 | 5320383 | 5320437 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon5 | 5323360 | 5323506 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS5 | 5323360 | 5323506 |
| chr_4 | g15397 | g15397.t1 | exon | g15397.t1.exon6 | 5323564 | 5323755 |
| chr_4 | g15397 | g15397.t1 | cds | g15397.t1.CDS6 | 5323564 | 5323755 |
| chr_4 | g15397 | g15397.t1 | TSS | g15397.t1 | 5323812 | 5323812 |
| chr_4 | g15397 | g15397.t1 | TTS | g15397.t1 | NA | NA |
Sequences
>g15397.t1 Gene=g15397 Length=1728
ATGATTAAGTTATTGATAGTGATGTTTTTATGTGGCATAAGTGTGGCGCTTAATGATGAT
CAAAGTGATCCTGTTGTATGCTATAGCATGGGTTGTGTTAGAGGAAAAAATTATGTTGGA
AATATAAAACCATATGAAGGATTTTTTGGAATCCCATACGTTAAACAACCAGTTGGTGAT
TTAAGATTAAAAGATCCACAGCCAATAACTGAAAAATTCACAGAAATTTACAATGCAACA
GAAGAAAAAATGTTTTGTGCACAGAAAAATTATTTATTGCCAAATCCAAGTGTTATCGGC
GTTGAAGATTGTCTTTATCTTTATGTTTATCGTCCTAAGAATTGGCAACGTAAAAACAAA
AAGCCTTTGCCTATTCTGATTTACATTCATGGAGGAGCATTCTTTGCTGGTATTGCTGGA
CCATCAGTTACAGGTGGTGATTACATCATGGACACAGAAGATGTAATTTTTGTTACTATG
TCATACCGTCTCGGTCCTCTTGGATTTCTTTCCACTGGTGATGAAAATATAAGCGGTAAC
TTCGGTTTGAAAGATCAAGCAATGGCTATAAAATGGGTCAAAGATAATATTTATGCATTT
GGAGGTGATCCAAACAATATCGCTTTAATGGGTCAATCAGCTGGTGCAGCATCAGTTCAT
CTTCATATGATGAGTCCGTGGAGTTGTCGCAATTTCCATAAAGCTATAATACTCTCAGGC
AATGGAATTGCACCTTACGCTTATGTACTCAAAGATCCATTTCAACAAGCAAGAAAATAT
GCAATTGCATCTGGTATGAAATTAACATCAGAAATGACAAAACAGGATTTAGCTAATTAT
TTAAGAAACGTTGATACAAAAACACTTCTTGATGCAACAGATAGTTTTAAAATTTGGTCA
ATTGATCCTTTAGTCATTTCACGACCAGTAGTTGAAGATTGTAGCAAAGTTCATGGATTT
TTATGTGAAGATCCAGTGAAAATGTGGCGAAATGGAATTCATTCGCATATTCCATTGATA
ACTGGTTATATGGATGGTGATGGTGGTGTCAGATCTTTACAATATTTTGAAAATCAAGAG
CTTTTAGAAGAACTTAATAACAATCTTGATGGACTTATGCCAAAATTGCTTGAAATTGTT
GATCCATTATCAGAAAATGTCACAACGAATCGATGGAAACAAGTTAAAGATCGATATTTT
AATGGTCAAAATAAATTGGAACCAAATCAATGGAAAAATCTCATGAAACTTTATACAGAT
CGTTCTTTTGTAACCCCAATGGCTGACACATTATTGCAATTAGTTAAAAGTGAATCAAAA
TCTCCAGCTTATTTGTATAAATTCAATTTTCGTGGTCCACTTTCGAATTCAATTTTGTAT
ACTGGAACAACTAAAGATTTTGGAACTGTTCATTCTGATGAATTAATTTATTTGTTAAAA
TCACCACTGCTGTTTCCACAACAATATGATGCCAATTCAAGAGAAGGAATTTTTAGATCG
AGATTTGTGAAATTCTTTACTTATTTTGCAATTAATGGAAAACCACCAAAAGCAAACAAC
AAAACTCTTCACAGATGCATTAAAAATGAAGCATTCGCAGTTGGAACAAGACAATTGAAA
TGTTCTTATATTGATTTTGATGAGAAAATTTCAATTAAAGCTGAAGGTGCAATTGATAAT
GATGCTGTTGATTTTTGGAATCAAATTGATACTACTTTAGTTAAATAG
>g15397.t1 Gene=g15397 Length=575
MIKLLIVMFLCGISVALNDDQSDPVVCYSMGCVRGKNYVGNIKPYEGFFGIPYVKQPVGD
LRLKDPQPITEKFTEIYNATEEKMFCAQKNYLLPNPSVIGVEDCLYLYVYRPKNWQRKNK
KPLPILIYIHGGAFFAGIAGPSVTGGDYIMDTEDVIFVTMSYRLGPLGFLSTGDENISGN
FGLKDQAMAIKWVKDNIYAFGGDPNNIALMGQSAGAASVHLHMMSPWSCRNFHKAIILSG
NGIAPYAYVLKDPFQQARKYAIASGMKLTSEMTKQDLANYLRNVDTKTLLDATDSFKIWS
IDPLVISRPVVEDCSKVHGFLCEDPVKMWRNGIHSHIPLITGYMDGDGGVRSLQYFENQE
LLEELNNNLDGLMPKLLEIVDPLSENVTTNRWKQVKDRYFNGQNKLEPNQWKNLMKLYTD
RSFVTPMADTLLQLVKSESKSPAYLYKFNFRGPLSNSILYTGTTKDFGTVHSDELIYLLK
SPLLFPQQYDANSREGIFRSRFVKFFTYFAINGKPPKANNKTLHRCIKNEAFAVGTRQLK
CSYIDFDEKISIKAEGAIDNDAVDFWNQIDTTLVK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g15397.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 2 | 572 | 9.8E-131 |
| 2 | g15397.t1 | PANTHER | PTHR11559:SF405 | ACETYLCHOLINESTERASE-LIKE PROTEIN | 14 | 569 | 2.0E-121 |
| 3 | g15397.t1 | PANTHER | PTHR11559 | CARBOXYLESTERASE | 14 | 569 | 2.0E-121 |
| 1 | g15397.t1 | Pfam | PF00135 | Carboxylesterase family | 23 | 525 | 3.2E-115 |
| 9 | g15397.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 16 | - |
| 10 | g15397.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 11 | g15397.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 11 | - |
| 12 | g15397.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 12 | 16 | - |
| 8 | g15397.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 17 | 575 | - |
| 14 | g15397.t1 | ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. | 200 | 215 | - |
| 4 | g15397.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 22 | 518 | 5.35E-109 |
| 6 | g15397.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 16 | - |
| 13 | g15397.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 5 | g15397.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 22 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K01063 (juvenile-hormone esterase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
