Gene loci information

Transcript annotation

  • This transcript has been annotated as Cysteine protease ATG4B.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15561 g15561.t1 TTS g15561.t1 5867661 5867661
chr_4 g15561 g15561.t1 isoform g15561.t1 5867669 5868927
chr_4 g15561 g15561.t1 exon g15561.t1.exon1 5867669 5868320
chr_4 g15561 g15561.t1 cds g15561.t1.CDS1 5867669 5868320
chr_4 g15561 g15561.t1 exon g15561.t1.exon2 5868411 5868713
chr_4 g15561 g15561.t1 cds g15561.t1.CDS2 5868411 5868713
chr_4 g15561 g15561.t1 exon g15561.t1.exon3 5868779 5868927
chr_4 g15561 g15561.t1 cds g15561.t1.CDS3 5868779 5868927
chr_4 g15561 g15561.t1 TSS g15561.t1 5869006 5869006

Sequences

>g15561.t1 Gene=g15561 Length=1104
ATGGATCTCTTGTTGGCAGACAACATTGGATACGATGTTTGGGAAGTTGAAGATATACCA
TCGACAGCTGATGAAATTATTGTGCTGGGAAAAACTTATAAATATGAAGATTTAGAAAAA
ATTAGAGATGACGTGCAGTCAAGATTATGGTGCACATATAGGAAAGGATTTTCACCATTA
GGTTCACCACAATACACATCAGATAAAGGTTTTGGTTGTATGATGCGATGCGGTCAAATG
TTACTGGCAGAGGCATTAACTCAATTACATATTGGTCGACATTGGCGATGGACGATTGAT
ACCAAAGATCCAATTTACCTCGAAATTGTTAATAAATTTGAAGATACAAAAAGTGCAGTT
TATGGCATTCATCAAATCGCAATTATGGGACAAGATTCAGGAAAAAAAATTTCAGAGTGG
TACAGTCCTAATGTGATAGCTCAAGTGATAAGAAAATTAGTACGATTTGATGAATTTTCA
AATCTTCAAGTACACGTAGCACTTGATCATCAATTAGCATTAGATGACATCATTGAAATC
ACAACACCATTACTACTGATTATACCACTTCGTTTAGGTCTCAATGAATTAAATCCAATT
TACATCCCAGCACTAAAGCGGTGTTTTGAAATTCCTGGTACCCTTGGTATCATTGGTGGT
CGACCAAATCAAGCTTTATATTTTGTTGGCTATGTTGGTGATGAAGCATTGTACCTTGAT
CCACATACATGTCAGAAAAGTGGCAGCATTAATAATAAAGAATTACAATGTGAAATTGAA
ATGGATGACACTTTTCATCAAAAGCATGCAGGAAGAATAAATTTTAATTCCATGGATCCA
TCAATTGCTGTTGCATTTTTATGTAAATCACAAAAAGAATTTGATGAATTAATTGAAGCA
TTAAGAAATGTTGAGAAAGAAATGACTCCACTTTTTGAAATTGTTGAACAACGAGCACAA
CCATGGATATCAACATCGATGAGTAGTAAAGATTTAGAACATGATTTGAGTATCATTAGT
GGCGGTGGTGAAGGAAATCAAGAATTTGAAAAGGTTGAAAAAGAAGAAGATGACGATGAT
GATGATTTTGAAATTATTGATTAA

>g15561.t1 Gene=g15561 Length=367
MDLLLADNIGYDVWEVEDIPSTADEIIVLGKTYKYEDLEKIRDDVQSRLWCTYRKGFSPL
GSPQYTSDKGFGCMMRCGQMLLAEALTQLHIGRHWRWTIDTKDPIYLEIVNKFEDTKSAV
YGIHQIAIMGQDSGKKISEWYSPNVIAQVIRKLVRFDEFSNLQVHVALDHQLALDDIIEI
TTPLLLIIPLRLGLNELNPIYIPALKRCFEIPGTLGIIGGRPNQALYFVGYVGDEALYLD
PHTCQKSGSINNKELQCEIEMDDTFHQKHAGRINFNSMDPSIAVAFLCKSQKEFDELIEA
LRNVEKEMTPLFEIVEQRAQPWISTSMSSKDLEHDLSIISGGGEGNQEFEKVEKEEDDDD
DDFEIID

Protein features from InterProScan

Transcript Database ID Name Start End E.value
4 g15561.t1 MobiDBLite mobidb-lite consensus disorder prediction 338 367 -
5 g15561.t1 MobiDBLite mobidb-lite consensus disorder prediction 351 367 -
2 g15561.t1 PANTHER PTHR22624 CYSTEINE PROTEASE ATG4 20 335 1.2E-102
1 g15561.t1 Pfam PF03416 Peptidase family C54 39 299 3.5E-88
3 g15561.t1 SUPERFAMILY SSF54001 Cysteine proteinases 13 309 1.32E-99

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

There are no GO annotations for this transcript.

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values