Gene loci information

Transcript annotation

  • This transcript has been annotated as Fatty acid synthase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15616 g15616.t1 isoform g15616.t1 6098962 6106275
chr_4 g15616 g15616.t1 exon g15616.t1.exon1 6098962 6099573
chr_4 g15616 g15616.t1 cds g15616.t1.CDS1 6098962 6099573
chr_4 g15616 g15616.t1 exon g15616.t1.exon2 6099833 6099954
chr_4 g15616 g15616.t1 cds g15616.t1.CDS2 6099833 6099954
chr_4 g15616 g15616.t1 exon g15616.t1.exon3 6100017 6100951
chr_4 g15616 g15616.t1 cds g15616.t1.CDS3 6100017 6100951
chr_4 g15616 g15616.t1 exon g15616.t1.exon4 6101022 6101371
chr_4 g15616 g15616.t1 cds g15616.t1.CDS4 6101022 6101371
chr_4 g15616 g15616.t1 exon g15616.t1.exon5 6101958 6102969
chr_4 g15616 g15616.t1 cds g15616.t1.CDS5 6101958 6102969
chr_4 g15616 g15616.t1 exon g15616.t1.exon6 6103029 6103922
chr_4 g15616 g15616.t1 cds g15616.t1.CDS6 6103029 6103922
chr_4 g15616 g15616.t1 exon g15616.t1.exon7 6103981 6104326
chr_4 g15616 g15616.t1 cds g15616.t1.CDS7 6103981 6104326
chr_4 g15616 g15616.t1 exon g15616.t1.exon8 6104398 6104663
chr_4 g15616 g15616.t1 cds g15616.t1.CDS8 6104398 6104663
chr_4 g15616 g15616.t1 exon g15616.t1.exon9 6104729 6104748
chr_4 g15616 g15616.t1 cds g15616.t1.CDS9 6104729 6104748
chr_4 g15616 g15616.t1 exon g15616.t1.exon10 6104808 6105096
chr_4 g15616 g15616.t1 cds g15616.t1.CDS10 6104808 6105096
chr_4 g15616 g15616.t1 exon g15616.t1.exon11 6105620 6106275
chr_4 g15616 g15616.t1 cds g15616.t1.CDS11 6105620 6106275
chr_4 g15616 g15616.t1 TSS g15616.t1 6106320 6106320
chr_4 g15616 g15616.t1 TTS g15616.t1 NA NA

Sequences

>g15616.t1 Gene=g15616 Length=5502
ATGACTTCAAGTGAAGAACGCCGCATTCTTACTCGTGTAAAAGTTGATAGGGATGATGAG
ATTATCATATCAGGCATTTCTGGACGTTTTCCTAATTCTAAGAATGTTGAAGAATTAAGT
TACAATCTGTACAACAAGATTGATATGGTTGATGATGTTGAAAGACGTTGGAAACATCTA
AATGACGAAATGCCCAAGCGTTATGGAAAAACTGTAAATTTAGAGAAATTCGATGCTTCA
TTTTTCTCTATTAATTACAAACAAGCGCACAACATGGATCCACAAGCAAGAATTCTACAA
GAGCATGCATATGAGGCAATTATGGATGCAGGTGTTGCTCCAAAATCTCTAAGAGGTAGT
AGAACTGGTGTCTTTATCAGTTGCTGTACGACTGAAGTAGATGAGCATTTTTATTTTGGT
ACTGCGATAAAGGATGGCATGGGTCTAACAGGCACAAGTCGTGCTTTATTGGCAAACAGA
ATTTCTTTTTCTATGGACCTCAAAGGGCCGTCGTTCACAATCGATTCGGCATGCAGCAGC
TCCGGTTATGCTCTCGATTTGGCTTTTAATGCTATAAGAACTGGTGAATGTGATGCTGCT
ATTGTTGGTGGCACAAATTTGCTTCTTCATCCAGCAACTACTTTACAATTTTTTAGACTT
GGAGTCTTAAGTAAAGATGGCTATTGTCGACCATTTGACAAGGATGCTTTAGGTTATTGT
CGTAGTGAAGCAATAACGGTGGTTTTTCTTCAGAAAAGAAAAGATGCTAAACGAATTTAT
GCTGAATTGGTTTATTCAAAAACAAATATTGATGGCTTTAAAGATGAAGGTCTTACTTAT
CCAAGCGGTAAAATTCAGACTAAATTATTAGCTGAATTTTATAAAGACCTTGATATTGAC
CCAAAAACAGTTGATTATGTTGAAGCGCATTGTGCTGGGACAAAAGTTGGCGATCCCGAA
GAATGTATAACTCTCGAAACTATTTTTTGCAATGATAGAACAAAACCATTACTTATTGGT
TCTGTCAAATCAAATATGGGACACACTGAAGGTTCATCATCACTTTGTTCTATCATAAAA
TCTATATTGATTTTTGAAAACAGAACAATTCCACCTAATATACATTTTACTGCACCTAGA
ACTGATATTCCTTCTTTAGTAGATGGAAGATTGAAAGTTGTTAACAAAATGGAAAAATTT
GATGGCAATCTCATTGGTGTCAATTCATTTGGTTTTGGTGGCGCAAATTTTCACTGTTTG
GTAAAAAGAAATCCAAAACAAAAAGAAAATCGAGGTATTCCTAAAGATGACATTCCTCGA
TTAGTTTTATGGAGTGGACGAACAGAAGAAGCTGTAAATGCTGTTTTAGAAAATATTTCA
TCACAACCTCTTGATGCCGAATTTATTGCTTTACTTCAAAACTCACAAATTTCTAATCCA
ACACTAAACACTTATCGCGGTTATGGAATTTATGCTAAAGATAATGAAAATACAAAATGT
CTTGCACATCATGTTAATAATTTTGCATCATCAAAAAGGCCTATTGTTTTCGTGTATAGT
GGAATGGGTTCACAATGGCCTCAAATGGGAGCAGATTTAATGAAAATTCCAATATTTGCA
TTAACAATTGAAAAGTGTCACAACATTTTGATCGAAAAGCAAATAAATCTAAAAGAAATC
ATAACATCAAGTGATACATTAATTTTTGAAAATATTTTAAATTCTTTTGTTGGCATCGCA
GCAATTCAAATTGGTTTAACAAATATTATGAATGCAATTGGATTGAAACCAGATTTTGTG
ATTGGTCATTCAGTTGGTGAATTAGGATGTGCATATGCTGATAATTGTTTGACTGAAGAA
GAAATGATTTTATGTGCATATTCACGTGGCATGGCAAGTCTTGAAAGTAAAGTTATATAT
GGTGCTATGGCAGCAGTTGGTGTTGGTTATGATGAACTTAAAAATATGCTGATTGATGGT
ATAGAAATTGCTTGTCATAATAGCGCAGATTCATCCACTATTTCTGGACCATCAGATTTG
ATTGATGTATTTGTAAAGAAATTGAAAGAGAAAAATATTTTTGCAAAAAAAGTTCAAACA
TCAAACATTGCATATCACAGCTCTTATATTGATCCACTTGGTCCAAATTTACTACGACGT
TTAAAAGATGTCATCAAAAATCCCAAAAAAAGATCTTCAAAATGGATTTGTTCAAGTGTC
CCGAAAGAAAATTGGAATGATTTTGATTGTCGTTTTTCATCAGCACAATATCATTCTAAT
AACCTTCTCAATCCAGTGCTATTTCAAGAAGCATCAGAAATTCTTCCAAAAGATGCTCTT
ACCATAGAAATCGCACCACATGGACTTTTACAATCTATAACTAAAAGATTATTGCCTGAT
GGTTTACATTTTAGTTTAACGAAGCGTGGAATTAGTGACAATTCACTTTATTTAATTAAA
TCTCTTGGAAAAATTTTTGAAAATGGCGTTGACATGGATATTTCAGCAATCTATCCACAA
ATAGAATTTCCAGTATCATCTGGTACACCAATGATTTCACCATTAATCAAATGGGATCAT
ACAGAAAACTGGTTTGTTCCAAAATATGATGATAAAGAGCACAATGACATGCAAATTATA
ATAAGCCTACAAGATTCAGAATATGGATTCATTTCGGGACATGAAATTGATGGACGAGTT
TTATTTCCTGCAACTGGATATCTTTTTCTCGCATGGAAACTTGCAGCATTACAAAATAAG
GAATTTTTTGATAAATTTGATGTTGAATTTGAAGATGTTAAATTTTTGCGTGCATGCAAT
ATTCCAGCTGATCCAAATGGAATCAAATTAACAGTTGTTGTTCAACGTGGAAGTGGAAAA
TTTGAAATAATTAATGGAAAAAGTACTGTTTGTACAGGAATTGTACGAATTGCATCAGAA
TCAAAAATGAGACAGTTTTATCATGAAGATTCGAAAAAGATTGAATTGAAAGCAAAAGAT
TTCTACAAAGAGCTTCGATTACGTGGTTATAATTATAAAGGTTTATTTAAATCAGTGATT
TCTTCACAATCAGATGGATCGAGTGGAAATATCAAATGGCAATCAAATTGGATTGTTTTT
CTTGATTGTCTTTTGCAATTACAAATTTTATCAAGAGACACACGTTCACTTGTATTGCCT
GTGGGCATAAAAAAGCTTACAATTAAAACAAGAGATCATTTGGCATTGGCATCAAAACTT
GATAAAAATGGAGTATTTAAAGCTTTCTATTCTTCCAAATTAAAAATTCTTCAGTGTGGT
GGTGTTGAAATAAGAGGAGTGCAAACTCAAACTGTTAACCGTCGTCCACCAAATGGAATT
CCAATACTTGAAAGTTATCAATTTATTCCACATTACAAGAATTTAGTTTTATCAAAAACT
GATATTGCAAGATTTTGCATTCAACTTGCAATTGAAAATTTTGCAACTGCAAAAATTTCT
GCGGAAATAAGAGAATTACTCGATGCTGATATTAAAAAAGGCATCATAAAACCACTTAAA
ATGAATGTTTTTAATGCTGATGAAATTGTTCAAGCATTCAAATTACTTGCAAGTGGTAAA
CATATTGGAAAAGTAGTTTTACGTATGCGTGAAATGGAAAATTCAGAAAAATCAGTACCA
ATATCAGTTTTGCCAAAAGTTTATTTCAATCCTAATTTATGTTACATTATTTGTGGTGGT
CTTGGTGGTTTTGGATTAGAATTAACTGATTGGCTTATTTTAAGAGGATGCAAAAATATA
ATTTTAAGTTCAAGTCGTGGAATTACAAATGATTATCAAAAAATTAGAATAAGTTTATGG
AAATCATATGGTGTAAAAGTCATCATAAGTACATCAGATATTACAACACGCGATGGATGT
ATTGAATTAATTACAACTGCATCTAATATAGCACCAGTTGGTGGAATATTTAATTTAGCT
GTAAAACTTCGTGATGGAATTCTCGAAAATCAAGATGCAAAAACTTTTACTGAATGCATG
GCACCAAAAGCTTTAGCAACTAAATATCTTCATGAAGTTTCTCGCAGTCGTTGTCCTCTT
TTGCATGAATTTGTTGTCTTTTCAAGTGTATCTTGTGGTCGTGGTAATGCAGGACAATCA
AATTATGGAATGGCAAATTCTGTAATGGAACGCATCATAGAACAACGTCATAAAATTGGA
TTACCTGGTAAAGCAATACAATGGGGAGCAATTGGTGATGTTGGTATAGTTGCTGATATG
CAAGAAGATAAAAATGATTTAGAAATCGGCGGAACATTACCACAACGAATTTCATCATGT
CTTGAAGTTCTTGATACATTGATGACAGTGAAAAATCCAATTGTCAGTAGCATGGTTGTT
GCTGAAAAACACAACAAAAATTCTGGAAAAGATGGAATTGTTAAAATGATTATGAATATA
ATGTCAATCAAAGATGTCAAAAGTCTTTCAATTGAAACAAAACTTTCTGAACTTGGTATG
GATTCATTAATGACAGTTGAAATTTCACAAGCACTTGAACGTGAATTTAATTTGTATATA
ACATCACAAGAGCTCAGATCTATTACATTACAACAATTAAATGCTTTAGAAAAAGATGGA
CATTTTGATGAAATTGAAAATCCAATTAATAAATTTCAATTTCTTTTACCAAGTTTGGAT
GAAGAAAAGGAAGCTTATAAATCAATAATTAAACTTGAAAGTAACAATAATAATGGTGAC
AAAGTACTTTTGATAACTGGAATTGAAGGAGTCGGAGGGAAAAATTATAAAAATTTTGCA
CGCAATTTAAATAATCCTACATATTTACTTCAAATGTCAAGTTGTTGGTATGCGAAAAGT
CTTGATGAAATGTATTCAGCTGTTGTTGATGATGTTTTAAAACTGTATGACAATGAAAAA
TCTTTCCTTTTGATTGGTTATTCATTTGGTTCAATATTAACATTGAAACTTGTAAACGCT
CTAGAATCGAAAGGAAAAACTGGCAAAGTTATCCTAATTGATGGCTCACCAAAACTTATG
CAACAAATTGTTCTACAATTTTTACCATCAAAAATAAAAAATGACAATGATATGGAAAAT
TTAGTTTTGAAACATTATTTCAGACTGATTTTTCCAAAAGAAAGAACTGATCGATTGAGC
AAAATATTACAAGAGATAACTTGGGAAGAAAAAATGTTAAAAGTTGAAGAAATTTTTGCA
AATTACAATTCAAACAGTATAGAATTTATTAAAAATCTATTTTTTGGATTGCTTCAACGT
ATAAAAATTGCTGCCAACTTAAATTTGAAGTCATTCAATCAGCTAAATTCACCAATTACT
TTGATAAAACCAAATGAAATTACATTGCATGAAATTGAAGATGACTATGGCCTGCAAATT
TATACTAAAAACAACATTCAAATCAACTCTTTAAAAGGAAATCATTCTAATATTATTGAA
AATGTTGATCTTTCTACACTTGTTAACAAAATTTTTTCTTAA

>g15616.t1 Gene=g15616 Length=1833
MTSSEERRILTRVKVDRDDEIIISGISGRFPNSKNVEELSYNLYNKIDMVDDVERRWKHL
NDEMPKRYGKTVNLEKFDASFFSINYKQAHNMDPQARILQEHAYEAIMDAGVAPKSLRGS
RTGVFISCCTTEVDEHFYFGTAIKDGMGLTGTSRALLANRISFSMDLKGPSFTIDSACSS
SGYALDLAFNAIRTGECDAAIVGGTNLLLHPATTLQFFRLGVLSKDGYCRPFDKDALGYC
RSEAITVVFLQKRKDAKRIYAELVYSKTNIDGFKDEGLTYPSGKIQTKLLAEFYKDLDID
PKTVDYVEAHCAGTKVGDPEECITLETIFCNDRTKPLLIGSVKSNMGHTEGSSSLCSIIK
SILIFENRTIPPNIHFTAPRTDIPSLVDGRLKVVNKMEKFDGNLIGVNSFGFGGANFHCL
VKRNPKQKENRGIPKDDIPRLVLWSGRTEEAVNAVLENISSQPLDAEFIALLQNSQISNP
TLNTYRGYGIYAKDNENTKCLAHHVNNFASSKRPIVFVYSGMGSQWPQMGADLMKIPIFA
LTIEKCHNILIEKQINLKEIITSSDTLIFENILNSFVGIAAIQIGLTNIMNAIGLKPDFV
IGHSVGELGCAYADNCLTEEEMILCAYSRGMASLESKVIYGAMAAVGVGYDELKNMLIDG
IEIACHNSADSSTISGPSDLIDVFVKKLKEKNIFAKKVQTSNIAYHSSYIDPLGPNLLRR
LKDVIKNPKKRSSKWICSSVPKENWNDFDCRFSSAQYHSNNLLNPVLFQEASEILPKDAL
TIEIAPHGLLQSITKRLLPDGLHFSLTKRGISDNSLYLIKSLGKIFENGVDMDISAIYPQ
IEFPVSSGTPMISPLIKWDHTENWFVPKYDDKEHNDMQIIISLQDSEYGFISGHEIDGRV
LFPATGYLFLAWKLAALQNKEFFDKFDVEFEDVKFLRACNIPADPNGIKLTVVVQRGSGK
FEIINGKSTVCTGIVRIASESKMRQFYHEDSKKIELKAKDFYKELRLRGYNYKGLFKSVI
SSQSDGSSGNIKWQSNWIVFLDCLLQLQILSRDTRSLVLPVGIKKLTIKTRDHLALASKL
DKNGVFKAFYSSKLKILQCGGVEIRGVQTQTVNRRPPNGIPILESYQFIPHYKNLVLSKT
DIARFCIQLAIENFATAKISAEIRELLDADIKKGIIKPLKMNVFNADEIVQAFKLLASGK
HIGKVVLRMREMENSEKSVPISVLPKVYFNPNLCYIICGGLGGFGLELTDWLILRGCKNI
ILSSSRGITNDYQKIRISLWKSYGVKVIISTSDITTRDGCIELITTASNIAPVGGIFNLA
VKLRDGILENQDAKTFTECMAPKALATKYLHEVSRSRCPLLHEFVVFSSVSCGRGNAGQS
NYGMANSVMERIIEQRHKIGLPGKAIQWGAIGDVGIVADMQEDKNDLEIGGTLPQRISSC
LEVLDTLMTVKNPIVSSMVVAEKHNKNSGKDGIVKMIMNIMSIKDVKSLSIETKLSELGM
DSLMTVEISQALEREFNLYITSQELRSITLQQLNALEKDGHFDEIENPINKFQFLLPSLD
EEKEAYKSIIKLESNNNNGDKVLLITGIEGVGGKNYKNFARNLNNPTYLLQMSSCWYAKS
LDEMYSAVVDDVLKLYDNEKSFLLIGYSFGSILTLKLVNALESKGKTGKVILIDGSPKLM
QQIVLQFLPSKIKNDNDMENLVLKHYFRLIFPKERTDRLSKILQEITWEEKMLKVEEIFA
NYNSNSIEFIKNLFFGLLQRIKIAANLNLKSFNQLNSPITLIKPNEITLHEIEDDYGLQI
YTKNNIQINSLKGNHSNIIENVDLSTLVNKIFS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
29 g15616.t1 CDD cd00833 PKS 19 421 2.08128E-143
28 g15616.t1 CDD cd08954 KR_1_FAS_SDR_x 1224 1461 7.96102E-63
20 g15616.t1 Gene3D G3DSA:3.40.47.10 - 19 423 1.9E-132
25 g15616.t1 Gene3D G3DSA:3.30.70.3290 - 438 866 6.0E-166
23 g15616.t1 Gene3D G3DSA:3.40.366.10 - 511 829 6.0E-166
26 g15616.t1 Gene3D G3DSA:3.10.129.110 - 876 1117 9.0E-69
19 g15616.t1 Gene3D G3DSA:3.40.50.720 - 1159 1177 7.4E-9
22 g15616.t1 Gene3D G3DSA:3.90.180.10 - 1178 1206 7.4E-9
18 g15616.t1 Gene3D G3DSA:3.40.50.720 - 1207 1467 1.6E-41
21 g15616.t1 Gene3D G3DSA:1.10.1200.10 - 1468 1549 3.0E-17
24 g15616.t1 Gene3D G3DSA:3.40.50.1820 - 1581 1822 3.3E-35
27 g15616.t1 Gene3D G3DSA:1.10.1470.20 Fatty acid synthase; domain 2 1680 1767 3.3E-35
9 g15616.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 16 1155 0.0
11 g15616.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 16 1155 0.0
8 g15616.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 1162 1832 0.0
10 g15616.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 1162 1832 0.0
6 g15616.t1 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 19 256 1.1E-61
1 g15616.t1 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 376 5.5E-34
7 g15616.t1 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 379 490 2.6E-30
3 g15616.t1 Pfam PF00698 Acyl transferase domain 516 796 1.3E-58
5 g15616.t1 Pfam PF14765 Polyketide synthase dehydratase 886 1098 8.7E-14
4 g15616.t1 Pfam PF08659 KR domain 1235 1412 1.6E-38
2 g15616.t1 Pfam PF00550 Phosphopantetheine attachment site 1480 1533 2.1E-7
30 g15616.t1 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 -
31 g15616.t1 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1497 1512 -
35 g15616.t1 ProSiteProfiles PS50075 Carrier protein (CP) domain profile. 1467 1544 8.671
33 g15616.t1 SMART SM00825 Beta-ketoacyl synthase 21 426 2.6E-96
32 g15616.t1 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 518 811 1.3E-20
34 g15616.t1 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1233 1414 2.4E-18
14 g15616.t1 SUPERFAMILY SSF53901 Thiolase-like 15 422 3.68E-66
13 g15616.t1 SUPERFAMILY SSF52151 FabD/lysophospholipase-like 515 801 3.14E-37
17 g15616.t1 SUPERFAMILY SSF55048 Probable ACP-binding domain of malonyl-CoA ACP transacylase 641 700 6.54E-8
15 g15616.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1233 1425 9.3E-24
16 g15616.t1 SUPERFAMILY SSF47336 ACP-like 1472 1533 4.06E-9
12 g15616.t1 SUPERFAMILY SSF53474 alpha/beta-Hydrolases 1557 1829 3.41E-20

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity MF
GO:0016740 transferase activity MF
GO:0006633 fatty acid biosynthetic process BP
GO:0004312 fatty acid synthase activity MF

KEGG

Orthology

Pathway

This gene does not belong to any pathways.

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values