Gene loci information

Transcript annotation

  • This transcript has been annotated as Fatty acid synthase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1564 g1564.t1 isoform g1564.t1 11896857 11905112
chr_3 g1564 g1564.t1 exon g1564.t1.exon1 11896857 11897670
chr_3 g1564 g1564.t1 cds g1564.t1.CDS1 11896857 11897670
chr_3 g1564 g1564.t1 exon g1564.t1.exon2 11897725 11898074
chr_3 g1564 g1564.t1 cds g1564.t1.CDS2 11897725 11898074
chr_3 g1564 g1564.t1 exon g1564.t1.exon3 11899782 11904141
chr_3 g1564 g1564.t1 cds g1564.t1.CDS3 11899782 11904141
chr_3 g1564 g1564.t1 exon g1564.t1.exon4 11904195 11904267
chr_3 g1564 g1564.t1 cds g1564.t1.CDS4 11904195 11904267
chr_3 g1564 g1564.t1 exon g1564.t1.exon5 11904331 11904461
chr_3 g1564 g1564.t1 cds g1564.t1.CDS5 11904331 11904461
chr_3 g1564 g1564.t1 exon g1564.t1.exon6 11904688 11905112
chr_3 g1564 g1564.t1 cds g1564.t1.CDS6 11904688 11905112
chr_3 g1564 g1564.t1 TSS g1564.t1 NA NA
chr_3 g1564 g1564.t1 TTS g1564.t1 NA NA

Sequences

>g1564.t1 Gene=g1564 Length=6153
ATGAGTTTTCTAAAAAGTAAAAGTGATGATGTGATTATAACTGGAATTGCTGGAAGATTT
CCAAAATCTCGAAATGTTCAGGAATTTGCATCGAATTTGTTTAATAAAATTGACATGACT
GATGACAGTGATGAACGTTTTAAAAATATTTCTGACGATGTTCCTCATCGTTCTGGTAAA
ATTTCTGACCTTGAAAAATTCGATACTTCTTTTTTTTCAATATTGAATGATCAAGCAAAG
TATACTGATCCACAAATGAGGATTCTACTCGAACATTCGTATGAAGCAATTTTAGATGCT
GGAATTTCACCTCAAACGTTAATTGGTAGCAATACTGGAGTTTTTGTTGGTTGCAGTGCT
TCAGAAGCAAAAAATTTTTATGTTAAAGGCTTTTGTGATATTCCAGATCAAATGTTCCTC
ACTGGAAACGGAATGTTTTATTTGGCAAATCGGATTTCTTATACATTTGGTTTATGTGGA
CCTTCATTAGTTCTCGATTCAGCATGTTCAAGTGCATCCCAAGCATTAGACTGTGCTTAC
AATTATATGAAAACAGGTTTATGCGAGGCTGCTTTAGTAGCTGGTACAAATTTAATCTTT
ACTCCTTTTATGTTTGAAAAATTCAATGCAATGAAAATACTTACTAATGATGGAATTTCT
AAAATATTCGATGAAGATTCAAAAGGTTTCGTTCGTGCTGAAACAATCAGTGTGATTTTC
TTACAAAATCGAAAAGTTGCAAAAAGAATTTATGCTCATTTGGTTCATTCTTTATCTAAT
AATGATGGTTTTAAGATCGAAGGTTCATCATTACCATCTAAAAAAATGCAACAAAAACTT
ATGACAAAATTTTATCAAGACATCAATTTTGATCCGCGTGAAATCAAATTCTTTGAAGCT
CACGCGACTGGAACTAAACAAGGTGATTTTCAAGAAGTTAATGCAATTGATGCTGTTTTA
TGCCAAAATCGATCAGATCAGTTGATTATCGGTAGTACAAAATCAAATATGGGTCACAGT
GAAGCCGCTAGTGGATTGGCATCGATAGCTAAAATTTTGATTGCTTTTGAAAATGGAAAA
TTTCCACCAAACATAAATTTGACAAAACTTCGTGATGATATTCCTGCATTCAAAGAAAAT
CGAATTGTTGTTGCTACTGATTCTATTGATTTAACTTCACCTTATATTGCTATGAATTCA
TTTGCACTAGGAAGTTCAAATGTTCATTTACTATTCAAACAAAACACTAAAGAAAAAACA
AATCAAAATCAAGAAAATGAAATTGAAAGAATGGTTTTATGGTCAGGAAGAACTGAAGAA
GCAATTCATTCAATTTTCGATGATATCACAAGTCGACCATTTGATATTGAATACATTGCA
TTGCTACAAAATTCTCAAATTCTTACACCAGATGCAAATTCTTATCGAGGTTTTGGAATA
TTTAAGAATGATCAAGAAAATTCAATTTCCATTGATCGCAATATACAATATTTTGATGGG
ATCAGAAAAAAAGTAGTTTTTGTATTTGCTGGAATGGGAACTCAATGGCATGGAATGGGA
CGTGATTTAATGAAAGTTCCATTATTTGCTGAATCCATTGAAGAAAGTCATGAAATACTG
TTTCAAAAAGGAATTAATTTGAAGGAAATTTTGAATTCAAATGAAGAAAAAACGTTTGAA
AATGTTTTGAATTCTTATGTTGGAATTGTTTCTATTGAAATTGCACTCACTGATGTTTTA
TTTGGTTTAAATATTAAACCTGACTTTATTGTTGGTCATTCAGTTGGTGAAATTGCTTGT
TCATATGCTGATGGTTGTTTGACAAGAGAAGAAGCTTTGACTATTGCTTATTTGAGAGCT
AAAATAATGCTTGATTTGAATATAAATGGAGGAGCAATGGTAGCTGTTGGAATGCATTTT
AATGAGCTTGAGAAAATTTTATCGAAAGAAATTGACATCGCTTGCCACAACAGTCAACAA
TCGACAACAATCAGTGGATCGAAAGCATCAATTGAGAAATTCACAGAACAACTAAAAGTG
CAGAAAATTTTTGTAAAAGAAGTTGCTTGTGCTGGAGTTCCGTTTCATAGTCGATATATG
AAAGATGTTGGACAAGAATTAGAAACAAAATTAAAATATCTGTTGAAATCTTCTAAAATT
CGTTCATCAAAATGGATAACATCAACTTATATAGAAGACAATGAGCAAAACCAACTTTGT
GATGCAAAATATCATGCTGATAATGTCAGAAATCCAGTTTATTTTGAAGAAGCTACATCA
AAATTACCTAAAAATGCAATCACAATTGAAATTTCACCAAATGGACTTTTTCAATCACTT
TTAAAATCAACATTAAATGAAAACATTTATGTAAGTCTTACAAATAAGAAAGCAGTTGAT
GGTAAAAATTATTTTATGAAATCACTTGGAAAAATCTTTCAATCGGGAGTTGATTTCAAT
ATAAGCAAACTTTATCCAACAATTGATTTTCCTGTATCACGTTGCACTCCAATGATTTCA
CCAATCATCAAATGGAATCATCAAGAAAGCCATTTTGTTGTTCAACATAAAAACTTGATG
GAATATCAGCGCAGAGTCAAAAATCTCAATTTTAAAGACAAAGAGCTTGAATATTTGTCT
CATCATATAATTGATGGAAGAGTTCTTGTACCTGCCACCTTTTGGATTGTTTATATTTGG
AAACAATTTGCTAAGATGCATGACATAAATTATGAAAGTTTAAGAGTTACACTTAAAAAT
GTAAAAATTTCTCGTGCCACTTATGTTAATTTGAAGCAAGAAATCGAAATAATTTCTACA
ATACATTGTTCAAATGGAAGTTTTGAAATAATGGAAGGGAAAAATTTGATTGCTAGTGGC
ATTATCGAACGCAATGAAAATCTCAAAATTTTTGAAATCGAAAATCAAACATATGAGAAA
GATTCAATTGTTTTAACTTTTGATGACTTTTATAAACATTTACGAGTTCTTGGGTATCAA
TATTTAGAAAAATTTAAATTAGTTCAGGAAATCACAGATGATGGATTGAAAGGAAAAATT
AAATGGAAAAATAATTGGGTTTTATTTTTAGACAATATAATTCAAACTACAGTATTAGCT
GAAAAATACGAAAGAGTTCATTTGCCATATTTTTTGAGTAAATTTTCAATTGATCCAATC
TTGCATAAAAAACTAATTGAAAAGTATAAAGGTTTTTTAATACCTTTTGAAAGAGCACAA
AATAAACAATACGTACGATGTGGTGGAGCTGAAAATGGAGATTTTACACCAATTATAATA
AATCAAAAACAACAAGGAAATCTTTTAGTAGAATTTTGCAAATTTATTTCTTTCGAAAAC
AGCAAGGAGTGTTTTGAAATTGTTGATGCATTAAAGATTTTAATATCTAGTCTCATGGAT
TTGAAATTTAAAATTAAATATAATTTTATTGAGATCAATAATGATCAGGAATATTTCATG
TATGATTATATAAATAAATTGTTTCAAAAGTATCCAATAGCTGTAAATGTTAAGTTATGG
GCAACTGAAAAAACTAAATTGGATGACATTGAAGTGATAAATGATCAAGTACTTTCAATA
CTAACTACTATTGATGCAGTTTTTACAAGTAATTGTATTCAAAATGAAGCTCTAATTGAG
AAAATTAAAAATATTCATTCTAATAGTGTAATAATTTCTCAAGAAAACTCAAATAAAGAA
ATATCAAATGACAAATTTGAAATTCTTTCAAAATTAAAATTATCTAATGAAAAAGCTTTA
TTTATGTTGAGATTTAAGCAACAAAAGGAAGAATTAAAAAAATTCAAAACAATTGAAATA
ACATCAGAAACTTCCGATTGGCTTGAAAATCTAAAAGAAGAAATCAAAAACTTTTCAAAC
AATAATTTTGATTCAATTATTTTGTATTCTCAAAAATCTAAAGGAATTTCTGGTTTACTT
GGCTTTTTCAACTGTTTAAGATTAGAATTTAATGAAATTAATTTCAAATGTTTTATGATT
GAAGACCTAAATGCACTTAAATTTGATATTGATGATCCATTTTATAAAAATCAATTAGAA
AAAGGTTTTACAGTCAATGTACTGAAAAATAATGAATGGGGAAGTTATCGACATATTGAT
TTAGAAGAAGATACTTCACTTAAACCATATGATGGTCATTGCTTTGCAAATTATTCAATG
ACCGGAAATCTTTCAACTTTAAAATGGTTTGATGGACCTTTCAATGAAATTTCTGAAGAT
GATCTTATAAAAGTTCAATATGCAGCATTAAATTTCAAAGATATTGTTTATGCTTTTGGA
CGAATTCCTGACGAAAATTGTTTCATGAGAGAATGCTCGATAGGATTTGAATTCTCAGGA
ATTCGAATTAAAACTGGAGAACGTGTGATGGGAATAGTTTCAAGACAAGGATTATCATCA
TATATCAAATACAACCCGAAAAAAACACTTAATGTTCCTGAAGATTTAACATTAGAAGAT
GCAGCAACTATTCCAATGGCATATGTCACCACTTTCTTTTCGGTTTTTGAAATGACTAAA
ATTGAGAAAGGAAATTCAATTTTGATTCATTCTGGTGCTGGCGCTGTAGGTCAAGCTGCA
ATTCAAATAGCTTTTGCTTATGGTTTAGAAGTTTTTACAACTGTTGGCACTGATGAAAAA
CGAGAATTTTTACTTAAAACTTTTCCGAAATTAAAAGAAGAAAATATTGGAAATTCTCGT
GACACTTCATTTTTAGAAATGATTATGGAAAGAACTCAAAACAAAGGAGTCGATTACGTG
CTGAACTCACTTGCTGGTGATAAAATGATTGCTTCATTGAATTGTTTGGGTCAAAATGGA
ATTTTCTTAGAAATCGGAAGAGCTGATTTAGTTCAAAATACTAGGATTAGTTTCAATTTT
ATCAAGAAAAATATTTCGATTAAGTTAGTTATGGTTGACAAAATTGATTGGGCAAGTGAT
CAAGGCGAGAGAGTAAAACAAATGATGATAAATGGTTTTAAAGAAAGAATCATAAAACCA
TTGACTCGAACTGTTTTCGAAGCAAATGAAATTAAAAAAGCTTTTCAACACATGTCAACT
GGCAATCACATTGGAAAAATTTTGATAAAAATGCGTGAAAATGAATATGATTTATCAACT
ATTCCTATTAATATCACATCGAGATTTTATTGCAATTCTGAGTATTCTTATATCGTTGTT
GGTGGTCTTGGTGGACTTGGACTGGAATTTTCTCATTGGTTAATTGAAAGAAAATGTAGA
AAATTGATATTAAGCTCAAGCCGTGGAATTAGCAATCAATATCAAGCATTTAAAATTAAA
TATTGGAAATCATTTGGAATTGAAGTCATTGTGAACACATCAAATGTTCTAACTGAAGCA
GGTTGTGAAAAACTCATTAAAACAGCAATGACTTTAGGTCCAGTTGGCGGAATTTTTAAT
TTTGCTGCTGTCATACGTGATGCTGAATTTGAAAATCACACAATTGAAGATTTCAATCAA
TCTCTGGCACCAAAAGCTTTGGCTACAAAATTCTTGCATGAATTATCACTAAAATATTGT
CCAATGTTGAAACATTTTGTTGGTTATTCAAGTATCATGTGTGGTCGAGGATATCCAGGT
CAAACAACTTATGGAATGGCAAATTCGATCATGGAAAGAATCATTGAAGAGCGATATGAG
ATGGGACTGCCAGCAAAAGTTATTCAATGGGGTCCAATCGGTGATGTCGGCTTACTTGCT
GATGTTGAATTGAATCGGAAAATGAAATTGAATTTTGAATTTCCAATGCAATCACTTGCA
TCATTTTTAGAGCAACATGATATTCTTTTAAATCATCCTGAACCAATTGTTGCTTGCACA
GTGATTTTTAATAAGAATGATAAATCTACTGATGAGAAGAAAAATTTCATCGAAATGTTG
ATGGAAGTTTTAAATATTGAAGATCGAAAGTCAATTTCAATGAGTTCAACATTTTCACAA
CTTGGCATTGATTCGCTTGCTGGAATAGAAATACAACAAATGATTGAAAGAAATTATGGT
GTTCTAATAGAATCTAATGAATTGAGAAACTTAACTATTTTCGAATTGGATGAAAAAATT
TCTAAAAAAACAATAAATAATTCTTTGTTTTAA

>g1564.t1 Gene=g1564 Length=2050
MSFLKSKSDDVIITGIAGRFPKSRNVQEFASNLFNKIDMTDDSDERFKNISDDVPHRSGK
ISDLEKFDTSFFSILNDQAKYTDPQMRILLEHSYEAILDAGISPQTLIGSNTGVFVGCSA
SEAKNFYVKGFCDIPDQMFLTGNGMFYLANRISYTFGLCGPSLVLDSACSSASQALDCAY
NYMKTGLCEAALVAGTNLIFTPFMFEKFNAMKILTNDGISKIFDEDSKGFVRAETISVIF
LQNRKVAKRIYAHLVHSLSNNDGFKIEGSSLPSKKMQQKLMTKFYQDINFDPREIKFFEA
HATGTKQGDFQEVNAIDAVLCQNRSDQLIIGSTKSNMGHSEAASGLASIAKILIAFENGK
FPPNINLTKLRDDIPAFKENRIVVATDSIDLTSPYIAMNSFALGSSNVHLLFKQNTKEKT
NQNQENEIERMVLWSGRTEEAIHSIFDDITSRPFDIEYIALLQNSQILTPDANSYRGFGI
FKNDQENSISIDRNIQYFDGIRKKVVFVFAGMGTQWHGMGRDLMKVPLFAESIEESHEIL
FQKGINLKEILNSNEEKTFENVLNSYVGIVSIEIALTDVLFGLNIKPDFIVGHSVGEIAC
SYADGCLTREEALTIAYLRAKIMLDLNINGGAMVAVGMHFNELEKILSKEIDIACHNSQQ
STTISGSKASIEKFTEQLKVQKIFVKEVACAGVPFHSRYMKDVGQELETKLKYLLKSSKI
RSSKWITSTYIEDNEQNQLCDAKYHADNVRNPVYFEEATSKLPKNAITIEISPNGLFQSL
LKSTLNENIYVSLTNKKAVDGKNYFMKSLGKIFQSGVDFNISKLYPTIDFPVSRCTPMIS
PIIKWNHQESHFVVQHKNLMEYQRRVKNLNFKDKELEYLSHHIIDGRVLVPATFWIVYIW
KQFAKMHDINYESLRVTLKNVKISRATYVNLKQEIEIISTIHCSNGSFEIMEGKNLIASG
IIERNENLKIFEIENQTYEKDSIVLTFDDFYKHLRVLGYQYLEKFKLVQEITDDGLKGKI
KWKNNWVLFLDNIIQTTVLAEKYERVHLPYFLSKFSIDPILHKKLIEKYKGFLIPFERAQ
NKQYVRCGGAENGDFTPIIINQKQQGNLLVEFCKFISFENSKECFEIVDALKILISSLMD
LKFKIKYNFIEINNDQEYFMYDYINKLFQKYPIAVNVKLWATEKTKLDDIEVINDQVLSI
LTTIDAVFTSNCIQNEALIEKIKNIHSNSVIISQENSNKEISNDKFEILSKLKLSNEKAL
FMLRFKQQKEELKKFKTIEITSETSDWLENLKEEIKNFSNNNFDSIILYSQKSKGISGLL
GFFNCLRLEFNEINFKCFMIEDLNALKFDIDDPFYKNQLEKGFTVNVLKNNEWGSYRHID
LEEDTSLKPYDGHCFANYSMTGNLSTLKWFDGPFNEISEDDLIKVQYAALNFKDIVYAFG
RIPDENCFMRECSIGFEFSGIRIKTGERVMGIVSRQGLSSYIKYNPKKTLNVPEDLTLED
AATIPMAYVTTFFSVFEMTKIEKGNSILIHSGAGAVGQAAIQIAFAYGLEVFTTVGTDEK
REFLLKTFPKLKEENIGNSRDTSFLEMIMERTQNKGVDYVLNSLAGDKMIASLNCLGQNG
IFLEIGRADLVQNTRISFNFIKKNISIKLVMVDKIDWASDQGERVKQMMINGFKERIIKP
LTRTVFEANEIKKAFQHMSTGNHIGKILIKMRENEYDLSTIPINITSRFYCNSEYSYIVV
GGLGGLGLEFSHWLIERKCRKLILSSSRGISNQYQAFKIKYWKSFGIEVIVNTSNVLTEA
GCEKLIKTAMTLGPVGGIFNFAAVIRDAEFENHTIEDFNQSLAPKALATKFLHELSLKYC
PMLKHFVGYSSIMCGRGYPGQTTYGMANSIMERIIEERYEMGLPAKVIQWGPIGDVGLLA
DVELNRKMKLNFEFPMQSLASFLEQHDILLNHPEPIVACTVIFNKNDKSTDEKKNFIEML
MEVLNIEDRKSISMSSTFSQLGIDSLAGIEIQQMIERNYGVLIESNELRNLTIFELDEKI
SKKTINNSLF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
27 g1564.t1 CDD cd00833 PKS 9 411 1.36418E-122
28 g1564.t1 CDD cd05195 enoyl_red 1423 1709 2.72175E-96
20 g1564.t1 Gene3D G3DSA:3.40.47.10 - 8 414 4.5E-118
18 g1564.t1 Gene3D G3DSA:3.30.70.3290 - 429 851 1.0E-149
23 g1564.t1 Gene3D G3DSA:3.40.366.10 - 501 816 1.0E-149
19 g1564.t1 Gene3D G3DSA:3.10.129.110 - 865 1105 5.9E-48
17 g1564.t1 Gene3D G3DSA:3.40.50.720 - 1283 1961 1.6E-232
22 g1564.t1 Gene3D G3DSA:3.90.180.10 - 1383 1729 1.6E-232
21 g1564.t1 Gene3D G3DSA:1.10.1200.10 - 1967 2048 2.0E-13
8 g1564.t1 PANTHER PTHR43775 FATTY ACID SYNTHASE 6 2044 0.0
9 g1564.t1 PANTHER PTHR43775:SF23 FATTY ACID SYNTHASE 3 6 2044 0.0
6 g1564.t1 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 245 8.3E-53
1 g1564.t1 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 251 367 2.9E-31
7 g1564.t1 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 372 480 1.0E-20
4 g1564.t1 Pfam PF00698 Acyl transferase domain 506 788 2.5E-62
3 g1564.t1 Pfam PF00107 Zinc-binding dehydrogenase 1535 1653 2.9E-13
5 g1564.t1 Pfam PF08659 KR domain 1736 1914 2.7E-36
2 g1564.t1 Pfam PF00550 Phosphopantetheine attachment site 1978 2030 1.4E-6
25 g1564.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 1734 -
26 g1564.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 1735 1755 -
24 g1564.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 1756 2050 -
29 g1564.t1 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 -
34 g1564.t1 ProSiteProfiles PS50075 Carrier protein (CP) domain profile. 1967 2050 10.24
32 g1564.t1 SMART SM00825 Beta-ketoacyl synthase 11 415 9.1E-83
31 g1564.t1 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 508 798 3.0E-39
30 g1564.t1 SMART SM00829 PKS_ER_names_mod 1402 1709 4.1E-103
33 g1564.t1 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1735 1916 2.5E-11
11 g1564.t1 SUPERFAMILY SSF53901 Thiolase-like 6 366 5.61E-60
10 g1564.t1 SUPERFAMILY SSF52151 FabD/lysophospholipase-like 504 788 9.68E-43
16 g1564.t1 SUPERFAMILY SSF55048 Probable ACP-binding domain of malonyl-CoA ACP transacylase 629 685 3.4E-8
14 g1564.t1 SUPERFAMILY SSF50129 GroES-like 1401 1522 2.69E-15
13 g1564.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1495 1652 5.45E-36
12 g1564.t1 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 1736 1922 6.26E-26
15 g1564.t1 SUPERFAMILY SSF47336 ACP-like 1976 2040 3.01E-8

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016746 acyltransferase activity MF
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity MF
GO:0016740 transferase activity MF
GO:0006633 fatty acid biosynthetic process BP
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed