Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Beta-hexosaminidase subunit beta.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15688 g15688.t2 TTS g15688.t2 6396093 6396093
chr_4 g15688 g15688.t2 isoform g15688.t2 6396300 6397198
chr_4 g15688 g15688.t2 exon g15688.t2.exon1 6396300 6396501
chr_4 g15688 g15688.t2 cds g15688.t2.CDS1 6396300 6396501
chr_4 g15688 g15688.t2 exon g15688.t2.exon2 6396576 6396783
chr_4 g15688 g15688.t2 cds g15688.t2.CDS2 6396576 6396783
chr_4 g15688 g15688.t2 exon g15688.t2.exon3 6396840 6397198
chr_4 g15688 g15688.t2 cds g15688.t2.CDS3 6396840 6396978
chr_4 g15688 g15688.t2 TSS g15688.t2 NA NA

Sequences

>g15688.t2 Gene=g15688 Length=769
TGCATCATGGGGTGCATCACATCCAGAACTTTTAACAAAATGCGGTGGAATATTTACTGG
CAAATATGGTCCAATAGATCCAACAATTGAAAGCAATTATGATTTCATCTTCAGTCTTTT
TGATGAAATTGTCGAAGTTTTTCCAGATGTTTATGTTCATTTAGGTGGTGACGAAGTTGG
ATTTGAATGCTGGCAATCAAATCAAAATATTTTGAACTTCATGAAACAACATAATATCAC
ATCGTTTGTTCAATTAGAAGAATTATACATTCAAAAATTGATTGATAAAGTTCATTCATT
AAATGTCAATTCGATTGTTTGGCAAGAAGTTTATACAAATGGAGTAAAATTACCCAAAGG
CACTGTTGTTCATGTATGGACTGGAAATCAAAGAAATTTACTATCGAGAATTACAAGAGA
CAATATGCCTGCTTTATTATCTGCTTGTTGGTATTTAGATCATCTTTCGACAGGTGGTGA
CTGGGTGAAATTTTATAACTGTGATCCTTGGGATTTCAGTGGTAATGACAATCAGAAAAA
ATTGGTTCTTGGTGGTGAAGCTTGCATGTGGAGTGAAGTTGTCGATGATGCAAATATTGT
TCAAAGAATTTTTCCGAGAACTTGTGCAACAGCTGAAAAATTATGGTCAACAGAAGATGT
AACAGACATTGAAGATGCAAAGCAACGACTTGAAGAACATTATTGTAGAATGAGACGAAG
AAATATTAATGCTCAACCTCCAAGTTCACCTGGATTTTGTTTAGTTTAA

>g15688.t2 Gene=g15688 Length=182
MKQHNITSFVQLEELYIQKLIDKVHSLNVNSIVWQEVYTNGVKLPKGTVVHVWTGNQRNL
LSRITRDNMPALLSACWYLDHLSTGGDWVKFYNCDPWDFSGNDNQKKLVLGGEACMWSEV
VDDANIVQRIFPRTCATAEKLWSTEDVTDIEDAKQRLEEHYCRMRRRNINAQPPSSPGFC
LV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g15688.t2 Gene3D G3DSA:3.20.20.80 Glycosidases 1 182 0e+00
2 g15688.t2 PANTHER PTHR22600 BETA-HEXOSAMINIDASE 6 173 0e+00
3 g15688.t2 PANTHER PTHR22600:SF38 BETA-HEXOSAMINIDASE SUBUNIT BETA 6 173 0e+00
5 g15688.t2 PRINTS PR00738 Glycosyl hydrolase family 20 signature 109 125 3e-07
4 g15688.t2 PRINTS PR00738 Glycosyl hydrolase family 20 signature 126 143 3e-07
1 g15688.t2 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 1 144 0e+00
6 g15688.t2 SUPERFAMILY SSF51445 (Trans)glycosidases 1 180 0e+00

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004563 beta-N-acetylhexosaminidase activity MF
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds MF
GO:0005975 carbohydrate metabolic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values