Gene loci information

Transcript annotation

  • This transcript has been annotated as Beta-hexosaminidase subunit beta.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15688 g15688.t3 TTS g15688.t3 6396093 6396093
chr_4 g15688 g15688.t3 isoform g15688.t3 6396609 6399074
chr_4 g15688 g15688.t3 exon g15688.t3.exon1 6396609 6396783
chr_4 g15688 g15688.t3 cds g15688.t3.CDS1 6396611 6396783
chr_4 g15688 g15688.t3 exon g15688.t3.exon2 6396840 6397205
chr_4 g15688 g15688.t3 cds g15688.t3.CDS2 6396840 6397205
chr_4 g15688 g15688.t3 exon g15688.t3.exon3 6397259 6397574
chr_4 g15688 g15688.t3 cds g15688.t3.CDS3 6397259 6397574
chr_4 g15688 g15688.t3 exon g15688.t3.exon4 6398452 6398567
chr_4 g15688 g15688.t3 cds g15688.t3.CDS4 6398452 6398567
chr_4 g15688 g15688.t3 exon g15688.t3.exon5 6398633 6398929
chr_4 g15688 g15688.t3 cds g15688.t3.CDS5 6398633 6398929
chr_4 g15688 g15688.t3 exon g15688.t3.exon6 6398984 6399074
chr_4 g15688 g15688.t3 cds g15688.t3.CDS6 6398984 6399074
chr_4 g15688 g15688.t3 TSS g15688.t3 6399129 6399129

Sequences

>g15688.t3 Gene=g15688 Length=1361
ATGCACAAAATTTTAATTTTTCTCACATTTTCTGTGACTCTTGCAACTTCCTATATTGTT
GATTATGGGCCAGTCGTGAAAGCAAGTCAAGGTGCTATTTGGCCAAAACCAAAAACTCAG
GTAATAAGTAACAATTTCAACATGCTTCGTCCATCAGAATTTACATTTGAAACTGTCGGT
AATTCATGTGATATTTTACAAAATGCATTGGAACGCTATCACACTATAATTGTGACACAT
TTAAGACGAATAAGAAATCGGGTAAAAAACGATCATGAAAATAATAAATGGAGAAGTAAA
CCCGAATATAGTGGACGATTGACGAGCGTAAAAGTGAACTTGAAACAAAAATGCGAAAAA
ATGCCGCACGTTGATATGGATGAATCATATGATCTTAATATTGCTGAACAACAAGCAACA
ATTGAATCAAATTCAATATGGGGATTATTAAGAGGACTTGAATCATTTTCTCAACTACTT
TATCATTCACCTGATGCGAAATTTCTTCTAATCAATGATACAAATATTTATGATGAACCA
CGCTTCAAACATCGAGGACTTTTAGTAGACACCAGCAGACATTTCATAAGCATTGCAATT
TTAAAAGAAATTCTTGATGGAATGGCTTACAATAAACTTAATGTTTTTCATTGGCACATT
GTTGATGATCATAGTTTTCCATATCAAAGCATAAAATATCCTGAATTAACTCGTGGTGCT
TATCATGAAAGTATGATTTATTCACAACAAGATATTGCTGATATAATTGAATATGCAAGA
ATGAGAGGAATTCGAGTTATGAGTGAATTCGACACACCTGGTCATACTGCATCATGGGGT
GCATCACATCCAGAACTTTTAACAAAATGCGGTGGAATATTTACTGGCAAATATGGTCCA
ATAGATCCAACAATTGAAAGCAATTATGATTTCATCTTCAGTCTTTTTGATGAAATTGTC
GAAGTTTTTCCAGATGTTTATGTTCATTTAGGTGGTGACGAAGTTGGATTTGAATGCTGG
CAATCAAATCAAAATATTTTGAACTTCATGAAACAACATAATATCACATCGTTTGTTCAA
TTAGAAGAATTATACATTCAAAAATTGATTGATAAAGTTCATTCATTAAATGTCAATTCG
ATTGTTTGGCAAGAAGTTTATACAAATGGAGTAAAATTACCCAAAGGCACTGTTGTTCAT
GTATGGACTGGAAATCAAAGAAATTTACTATCGAGAATTACAAGAGACAATATGCCTGCT
TTATTATCTGCTTGTTGGTATTTAGATCATCTTTCGACAGGTGGTGACTGGGTGAAATTT
TATAACTGTGATCCTTGGGATTTCAGTGGTAATGACAATCA

>g15688.t3 Gene=g15688 Length=453
MHKILIFLTFSVTLATSYIVDYGPVVKASQGAIWPKPKTQVISNNFNMLRPSEFTFETVG
NSCDILQNALERYHTIIVTHLRRIRNRVKNDHENNKWRSKPEYSGRLTSVKVNLKQKCEK
MPHVDMDESYDLNIAEQQATIESNSIWGLLRGLESFSQLLYHSPDAKFLLINDTNIYDEP
RFKHRGLLVDTSRHFISIAILKEILDGMAYNKLNVFHWHIVDDHSFPYQSIKYPELTRGA
YHESMIYSQQDIADIIEYARMRGIRVMSEFDTPGHTASWGASHPELLTKCGGIFTGKYGP
IDPTIESNYDFIFSLFDEIVEVFPDVYVHLGGDEVGFECWQSNQNILNFMKQHNITSFVQ
LEELYIQKLIDKVHSLNVNSIVWQEVYTNGVKLPKGTVVHVWTGNQRNLLSRITRDNMPA
LLSACWYLDHLSTGGDWVKFYNCDPWDFSGNDN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
14 g15688.t3 Gene3D G3DSA:3.30.379.10 Chitobiase 28 179 7.6E-40
15 g15688.t3 Gene3D G3DSA:3.20.20.80 Glycosidases 180 453 5.1E-99
3 g15688.t3 PANTHER PTHR22600 BETA-HEXOSAMINIDASE 19 452 5.3E-139
4 g15688.t3 PANTHER PTHR22600:SF38 BETA-HEXOSAMINIDASE SUBUNIT BETA 19 452 5.3E-139
21 g15688.t3 PIRSF PIRSF001093 B-hxosamndse_ab_euk_ 1 452 5.6E-144
5 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 139 159 2.6E-50
10 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 176 193 2.6E-50
9 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 205 226 2.6E-50
8 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 258 275 2.6E-50
7 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 301 319 2.6E-50
6 g15688.t3 PRINTS PR00738 Glycosyl hydrolase family 20 signature 323 336 2.6E-50
1 g15688.t3 Pfam PF14845 beta-acetyl hexosaminidase like 33 159 3.0E-21
2 g15688.t3 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 182 434 3.9E-70
17 g15688.t3 Phobius SIGNAL_PEPTIDE Signal peptide region 1 17 -
18 g15688.t3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 3 -
19 g15688.t3 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 4 12 -
20 g15688.t3 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 13 17 -
16 g15688.t3 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 18 453 -
11 g15688.t3 SUPERFAMILY SSF55545 beta-N-acetylhexosaminidase-like domain 33 181 1.17E-27
12 g15688.t3 SUPERFAMILY SSF51445 (Trans)glycosidases 182 450 1.21E-85
13 g15688.t3 SignalP_EUK SignalP-noTM SignalP-noTM 1 17 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004563 beta-N-acetylhexosaminidase activity MF
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds MF
GO:0005975 carbohydrate metabolic process BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values