General information for g1570.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sterol O-acyltransferase 1.
Parent gene
- The parent gene g1570 is located on chr_3: 11923393..11924474 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1570 | g1570.t1 | isoform | g1570.t1 | 11922351 | 11924474 |
| chr_3 | g1570 | g1570.t1 | exon | g1570.t1.exon1 | 11922351 | 11922878 |
| chr_3 | g1570 | g1570.t1 | cds | g1570.t1.CDS1 | 11922351 | 11922878 |
| chr_3 | g1570 | g1570.t1 | exon | g1570.t1.exon2 | 11923398 | 11924092 |
| chr_3 | g1570 | g1570.t1 | cds | g1570.t1.CDS2 | 11923398 | 11924092 |
| chr_3 | g1570 | g1570.t1 | exon | g1570.t1.exon3 | 11924144 | 11924474 |
| chr_3 | g1570 | g1570.t1 | cds | g1570.t1.CDS3 | 11924144 | 11924474 |
| chr_3 | g1570 | g1570.t1 | TSS | g1570.t1 | 11924636 | 11924636 |
| chr_3 | g1570 | g1570.t1 | TTS | g1570.t1 | NA | NA |
Sequences
>g1570.t1 Gene=g1570 Length=1554
ATGAGTAAAATTGATGATAAAGTTTTAAATGGGATTTTTGAAGATGTGCGTAAATTAAGC
TTAAAGTGCCACGACTTTGAAAAACAATTTATAAATAAAAGTGACAATGGAAAAAGTGAA
GAAAAATCGATGAAAAACAACCGAATGCATTTGCCTGATCGATATTTCCAAGCGAGAAAT
TCAGTTCTAACTGACTTGTTCGAAATTAAACACATTAGTACAATTTATCGAATTTTTATG
GTCATTTTTACACTTTTATTGCTGAATGTTTTTGTTTCGGATTTTGCTGATACTGGAAAA
ATTAATTTAGGACAACAAACAATTATAAAAGGTTTTAGTGGCTTTCAAAATGCTATAAAA
ATTTGGATTTGCATGCAATTTTCAATATTTTGCATTTATCCAGCATTTTTTATTTGGACA
AAAGCAACGAGAAAATTCTTTTTACTCAATGGTCCATTCATTGCAATATGGAATCTTCTT
GGAGTGCTCTCAGTCATTGCATACCAAGTTGCATTCATTTCATTCTCAACAAAAGCTGTT
TTAGATTACAAACTTGGTCCGGCAGCTTCAATGGCACTTCTAATGGAAGTTGTAAGATTT
ATGATGAAATCTCATGCATTTATTCGCTCGAGTGTTCCACGTGCATTTAAAAAGAAGCCA
CTGAAGAAAGAAGTGAAATCTTCTGACGATAGCGAACTAGAATATGACAATGACAATTCT
AAAATTAAAATTAACCAAAGTTTGCCAACTTTCAGGCAATTTTCTTATTTTCTATTTGCA
CCAACTCTTGTTTATCGTGACAATTATCCACGAACTCAACAAATTCGATGGCATTTTGTT
CTAAAATGTTTTCTCGAAGTGCTCTCATTGTTGTTTATTTTAAGTTTTCTTTTTGAGAGA
ACCATGCAACCGACATATTCAACTTTTGGCTCAAAATTTTATGAAATCGGTGTGAAGGAG
CTTACAACATCAGTTTTTAATAGCATGCTACCAGGATTGCTTTGCTTTTTGTGCGGATTT
TATGGTTTACTTCATGCATGGCAGAATGCATTTGCAGAGCTGCTGCGTTTTGCTGATAGG
ATGTTCTACTTAGATTGGTGGAATGCAACAAATTTTTCAGTCTATTATCGCACATGGAAT
TCTATCGTTCATGATTGGCTATATTTATACGTCTACAAGGATCTTTATGAGCATATTTTT
AAGAGAAATCGACAAATTTGTCAATTTTTAGTTTTTAGCATTTCAGCAATTTTCCATGAA
TACATTTTAGGATTCACATTTCGATTTTTTTATCCAGTACTTTTTATAGAATTTCAAGGA
ATTGGAGTGATTTTATTTTTCTTAATGAGAAAAGACATGAAATCACTTGGAAATTTTCTT
ATGTGGATGAGTTTAGCTATTGGAACTGGATTATTGTTAAGTTTGTATCATATGGAATAT
TATGCAAGAGAAAATTGTGAATACGATAAGGAAAAAATTATCAATTATTTCATTCCAATT
AGTTGGTCATGTAATGGACTTAAATATAACAAAAACTGGAAGCTTCAGTTTTGA
>g1570.t1 Gene=g1570 Length=517
MSKIDDKVLNGIFEDVRKLSLKCHDFEKQFINKSDNGKSEEKSMKNNRMHLPDRYFQARN
SVLTDLFEIKHISTIYRIFMVIFTLLLLNVFVSDFADTGKINLGQQTIIKGFSGFQNAIK
IWICMQFSIFCIYPAFFIWTKATRKFFLLNGPFIAIWNLLGVLSVIAYQVAFISFSTKAV
LDYKLGPAASMALLMEVVRFMMKSHAFIRSSVPRAFKKKPLKKEVKSSDDSELEYDNDNS
KIKINQSLPTFRQFSYFLFAPTLVYRDNYPRTQQIRWHFVLKCFLEVLSLLFILSFLFER
TMQPTYSTFGSKFYEIGVKELTTSVFNSMLPGLLCFLCGFYGLLHAWQNAFAELLRFADR
MFYLDWWNATNFSVYYRTWNSIVHDWLYLYVYKDLYEHIFKRNRQICQFLVFSISAIFHE
YILGFTFRFFYPVLFIEFQGIGVILFFLMRKDMKSLGNFLMWMSLAIGTGLLLSLYHMEY
YARENCEYDKEKIINYFIPISWSCNGLKYNKNWKLQF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g1570.t1 | PANTHER | PTHR10408:SF8 | O-ACYLTRANSFERASE | 33 | 497 | 1.7E-152 |
| 3 | g1570.t1 | PANTHER | PTHR10408 | STEROL O-ACYLTRANSFERASE | 33 | 497 | 1.7E-152 |
| 31 | g1570.t1 | PIRSF | PIRSF000439 | Oat_ACAT_DAG_ARE | 9 | 488 | 1.6E-103 |
| 1 | g1570.t1 | Pfam | PF03062 | MBOAT, membrane-bound O-acyltransferase family | 113 | 476 | 1.0E-27 |
| 16 | g1570.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 73 | - |
| 23 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 74 | 92 | - |
| 21 | g1570.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 93 | 118 | - |
| 24 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 119 | 139 | - |
| 13 | g1570.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 140 | 145 | - |
| 22 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 146 | 173 | - |
| 20 | g1570.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 174 | 184 | - |
| 25 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 185 | 202 | - |
| 12 | g1570.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 203 | 278 | - |
| 26 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 279 | 298 | - |
| 17 | g1570.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 299 | 328 | - |
| 30 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 329 | 347 | - |
| 15 | g1570.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 348 | 405 | - |
| 29 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 406 | 423 | - |
| 19 | g1570.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 424 | 428 | - |
| 27 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 429 | 448 | - |
| 14 | g1570.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 449 | 459 | - |
| 28 | g1570.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 460 | 478 | - |
| 18 | g1570.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 479 | 517 | - |
| 8 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 74 | 96 | - |
| 6 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 117 | 139 | - |
| 9 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 154 | 176 | - |
| 5 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 275 | 297 | - |
| 4 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 329 | 351 | - |
| 10 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 406 | 423 | - |
| 11 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 427 | 449 | - |
| 7 | g1570.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 456 | 478 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008374 | O-acyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00637 (sterol O-acyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed