Gene loci information

Transcript annotation

  • This transcript has been annotated as Thioredoxin.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_4 g15788 g15788.t1 TTS g15788.t1 6778383 6778383
chr_4 g15788 g15788.t1 isoform g15788.t1 6778535 6778879
chr_4 g15788 g15788.t1 exon g15788.t1.exon1 6778535 6778879
chr_4 g15788 g15788.t1 cds g15788.t1.CDS1 6778535 6778879
chr_4 g15788 g15788.t1 TSS g15788.t1 6778968 6778968

Sequences

>g15788.t1 Gene=g15788 Length=345
ATGTCAAATATTTTTCACATTGAAGATGAAGAAGATTTTCAGCAGCAACTTGCAAATGCT
GGTGAAAAACTTGTTGTTGTTGATTTTTTTGCAATGTGGTGTGGTCCATGTCAGAGTGTA
AATCCAAAGTTGGAAATTATTGCTGAAAAATATAGTGAAAAAATTGTTATTTTAAAAATT
GATACAGACAAGTGCAGACCATTGAAACTCAAATATGGAATTCGTTATGTTCCAACTTTT
ATTTTCTTCTGGAATGGTGAACGACTAGATGGAATTGTTGATGAAGCTAATTCCAGAAAA
GTTGAAAATTACATTGAAAAATATTTAGCTACAACTCATAACTAA

>g15788.t1 Gene=g15788 Length=114
MSNIFHIEDEEDFQQQLANAGEKLVVVDFFAMWCGPCQSVNPKLEIIAEKYSEKIVILKI
DTDKCRPLKLKYGIRYVPTFIFFWNGERLDGIVDEANSRKVENYIEKYLATTHN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g15788.t1 CDD cd02947 TRX_family 11 106 7.63686E-28
8 g15788.t1 Gene3D G3DSA:3.40.30.10 Glutaredoxin 2 113 1.1E-32
2 g15788.t1 PANTHER PTHR46115 THIOREDOXIN-LIKE PROTEIN 1 1 90 2.0E-29
3 g15788.t1 PANTHER PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 1 90 2.0E-29
9 g15788.t1 PIRSF PIRSF000077 Thioredoxin 1 109 6.7E-27
5 g15788.t1 PRINTS PR00421 Thioredoxin family signature 25 33 7.0E-6
6 g15788.t1 PRINTS PR00421 Thioredoxin family signature 33 42 7.0E-6
4 g15788.t1 PRINTS PR00421 Thioredoxin family signature 73 84 7.0E-6
1 g15788.t1 Pfam PF00085 Thioredoxin 9 106 2.1E-26
11 g15788.t1 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 -
12 g15788.t1 ProSiteProfiles PS51352 Thioredoxin domain profile. 1 114 11.277
7 g15788.t1 SUPERFAMILY SSF52833 Thioredoxin-like 1 109 9.62E-33

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0015035 protein-disulfide reductase activity MF
GO:0006662 glycerol ether metabolic process BP
GO:0045454 cell redox homeostasis BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values